Results 61 to 70 of about 16,711 (227)

Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQ(Q209P)-driven uveal melanomas in zebrafish [PDF]

, 2016
Mutations affecting Gαq proteins are pervasive in uveal melanoma (UM), suggesting they ‘drive’ UM pathogenesis. The ERK1/2-MAPK pathway is critical for cutaneous melanoma development and consequently an important therapeutic target.
Coupland, Sarah E, Dee, Christopher, Hurlstone, Adam FL, Mouti, Mai Abdel   +3 more
core   +2 more sources

Tumor Habitats Based on Multiparametric MRI Distinguish Atypical Glioblastoma From Primary Central Nervous System Lymphoma: Imaging‐Pathologic Correlation

Journal of Magnetic Resonance Imaging, Volume 63, Issue 1, Page 142-154, January 2026.
ABSTRACT Background Atypical glioblastoma (GBM) (minimal or no necrosis on MRI) and primary central nervous system lymphoma (PCNSL) are difficult to distinguish on MRI; whether tumor habitat can more accurately distinguish atypical GBM from PCNSL remains uncertain.
Meng‐nan Sun, Hui Wang, Yan‐ying Yang, Xiao‐jun Yu, Hai‐nan Li, Dan‐dan Fu, Dong‐Zhang, Ru‐yu Ai, Xiao‐yu Hua, Li‐chao Wang, Ming‐yao Lai, Chang‐zheng Shi, Lin‐bo Cai   +12 more
wiley   +1 more source

Performance of the MOLES and TFSOM-DIM scores in classifying choroidal nevi and melanoma

Scientific Reports
Choroidal nevi are common benign melanocytic lesions often incidentally found during routine ophthalmic examinations. Patients with choroidal nevi are frequently referred to ocular oncology centers to differentiate these from choroidal melanoma and to ...
David Jahnke, Carsten Grohmann, Bettina Fuisting, Christos Skevas, Martin S. Spitzer, Johannes Birtel   +5 more
doaj   +1 more source

P132

EJC Supplements, 2015
To research the characteristics of the inflammation immune disorders and cell destruction at the local level in the lacrimal and intraocular liquids in patients with choroidal melanoma.
M. Chernyavskaya, V. Chernych, A. Efremov, V. Atamanov   +3 more
doaj   +1 more source

Current management of choroidal melanoma in Serbia [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2018
Introduction/Objective. Uveal melanoma is the most common primary malignant intraocular tumor in adults, and approximately 90% of uveal melanomas originate from the choroid.
Bobić-Radovanović Anica
doaj   +1 more source

Radiation Maculopathy After Proton Beam Therapy for Uveal Melanoma: Optical Coherence Tomography Angiography Alterations Influencing Visual Acuity. [PDF]

, 2017
To analyze microvascular and structural changes in radiation maculopathy and their influence on visual acuity (VA), using optical coherence tomography (OCT) and OCT angiography (OCTA).
Daruich, A., Matet, A., Zografos, L.
core   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Pseudo-pigmented choroidal schwannoma with extraocular extension in an elderly patient

American Journal of Ophthalmology Case Reports
Purpose: To describe a rare case of clinically pigmented choroidal schwannoma with extraocular extension in an elderly patient. Observations: We report a case of a 79-year-old Black male who presented with a clinically pigmented, juxtapapillary choroidal
Arnulfo Garza Reyes, Chad Y. Lewis, Chau Pham, H. Culver Boldt, Lola P. Lozano, Nasreen A. Syed, Elaine M. Binkley   +6 more
doaj   +1 more source

Optical coherence tomography angiography in choroidal melanoma and nevus

Clinical Ophthalmology, 2018
Fariba Ghassemi,1,2 Reza Mirshahi,1,2 Kaveh Fadakar,1,2 Siamak Sabour3 1Retina & Vitreous Service, 2Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, 3Safety Promotion and Injury Prevention Research Centre, Department ...
Ghassemi F, Mirshahi R, Fadakar K, Sabour S   +3 more
doaj  

Uveal melanoma: Therapeutic consequences of doubling times and irradiation results; a review [PDF]

, 1992
Thirty-six of 39 published calculated doubling times (Td's) of uveal melanomas appeared to be longer than 60 days. Metastatic death occurs 35–40 Td's after dissemination.
Manschot, W.A., Strik, R. (Roel) van
core   +1 more source