Results 1 to 10 of about 24,682 (247)

Spectral domain-optical coherence tomography retinal biomarkers in choroidal neovascularization of multifocal choroiditis, myopic choroidal neovascularization, and idiopathic choroidal neovascularization [PDF]

Annals of Medicine, 2021
Objective To use optical coherence tomography (OCT) to compare retinal biomarkers of choroidal neovascularization (CNV) secondary to multifocal choroiditis (MFC), myopic choroidal neovascularization (mCNV), and idiopathic choroidal neovascularization ...
Rui Gao, Jingxue Ma, Zhengwei Zhang, Qingli Shang, Jialiang Duan   +4 more
doaj   +4 more sources

Diagnostic Challenges in Inflammatory Choroidal Neovascularization [PDF]

Medicina
Inflammation plays a key role in the induction of choroidal neovascularization (CNV). Inflammatory choroidal neovascularization (iCNV) is a severe but uncommon complication of both infectious and non-infectious uveitides.
Izabella Karska-Basta, Weronika Pociej-Marciak, Katarzyna Żuber-Łaskawiec, Anna Markiewicz, Michał Chrząszcz, Bożena Romanowska-Dixon, Agnieszka Kubicka-Trząska   +6 more
doaj   +2 more sources

Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration [PDF]

Brazilian Journal of Medical and Biological Research
Age-related macular degeneration (AMD), particularly the wet form characterized by choroidal neovascularization, is a leading cause of vision loss. Dysregulation of regulatory T cells (Tregs), key modulators of inflammatory responses, may contribute to ...
Juanjuan Li, Yuling Ren, Hua Li, Zhikun Zheng   +3 more
doaj   +2 more sources

Inflammatory Choroidal Neovascularization [PDF]

Ocular Immunology and Inflammation, 2020
Inflammatory choroidal neovascularization (iCNV) is an uncommon complication of uveitis resulting from direct involvement of the retinal pigment epithelium (RPE)-Bruch’s membrane complex by inflamm...
K. Bailey Freund, Rosa Dolz-Marco, Emmett T. Cunningham, Emmett T. Cunningham, Emmett T. Cunningham, Manfred Zierhut, Francesco Pichi, Francesco Pichi   +7 more
openaire   +3 more sources

MicroRNAs in laser-induced choroidal neovascularization in mice and rats: their expression and potential therapeutic targets

Neural Regeneration Research, 2021
Choroidal neovascularization characterizes wet age-related macular degeneration. Choroidal neovascularization formation involves a primarily angiogenic process that is combined with both inflammation and proteolysis.
Bridget Martinez, Philip V Peplow
doaj   +1 more source

Choroidal Vascular Density Quantification in High Myopia with or without Choroidal Neovascularization Using Optical Coherence Tomography Angiography

Journal of Ophthalmology, 2023
Purpose. The aim of this study was to analyze choroidal vascular density alteration in high myopia with or without choroidal neovascularization by using optical coherence tomography angiography (OCTA). Methods.
Xuehui Lu, Guihua Zhang, Lingping Cen, Yali Du, Lifang Liu, Chuang Jin, Haoyu Chen   +6 more
doaj   +1 more source

PAF‐induced inflammatory and immuno‐allergic ophthalmic diseases and their mitigation with PAF receptor antagonists: Cell and nuclear effects

BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022
Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley   +1 more source

Secondary choroidal neovascularization due to choroidal osteoma after 9 years follow-up

BMC Ophthalmology, 2021
Background Choroidal osteoma is a benign intraocular tumor that can increase risk of developing choroidal neovascularization. The visual prognosis is influenced by the tumor location, decalcification status, overlying RPE atrophy, presence of choroidal ...
Yun Zhang, Jia Fang, Shixin Zhao, Xiangjun She, Jun Wang, Lijun Shen   +5 more
doaj   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity

Molecular Genetics &Genomic Medicine, Volume 11, Issue 1, January 2023., 2023
BEST1 novel mutation causes Bestrophinopathies in six families with distinct phenotypic diversity. Abstract Purpose To report novel BEST1 variants in six Chinese families with bestrophinopathies of two different inheritance modes and analyze the intrafamilial phenotypic diversity.
Shangying Yang, Zhen Li, Wanyu Cheng, Meijiao Ma, Rui Qi, Xue Rui, Yinghua Ren, Xunlun Sheng, Weining Rong   +8 more
wiley   +1 more source