Results 101 to 110 of about 40,961 (260)

The dynamic changes of macrophage morphology in progression of choroidal neovascularization in laser-induced choroidal neovascularization mice model  [PDF]

open access: green, 2023
Nana Xu   +9 more
openalex   +1 more source

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

open access: yesEBioMedicine, 2016
Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness.
Yan Gong   +14 more
doaj   +1 more source

Deficiency of 2‐Oxoglutarate Carrier (Slc25a11) Drives RPE Epithelial‐to‐Mesenchymal Transition and Exacerbates Subretinal Fibrosis in Neovascular Age‐Related Macular Degeneration

open access: yesAging Cell, Volume 24, Issue 12, December 2025.
The diagram shows that OGC deficiency leads to mitochondrial dysfunction, which activates the PI3K/AKT/Slug pathway and triggers epithelial‐mesenchymal transition (EMT) in retinal pigment epithelial cells. This process promotes myofibroblast accumulation and subretinal fibrosis in laser‐induced CNV, contributing to the progression of AMD.
Mo Wang   +9 more
wiley   +1 more source

Peripapillary Choroidal Neovascularization Associated with Optic Nerve Head Drusen Treated with Anti-VEGF Agents

open access: yesCase Reports in Ophthalmology, 2015
Optic nerve head drusen can be associated with peripapillary choroidal neovascularization, in both the pediatric and adult population. These membranes can involve the macula, causing significant visual loss.
Norman A. Saffra, Benjamin J. Reinherz
doaj   +1 more source

IL10-driven STAT3 signalling in senescent macrophages promotes pathological eye angiogenesis [PDF]

open access: yes, 2015
Macrophage dysfunction plays a pivotal role during neovascular proliferation in diseases of ageing including cancers, atherosclerosis and blinding eye disease.
Apte, Rajendra S   +6 more
core   +2 more sources

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

open access: yesActa Ophthalmologica, Volume 103, Issue 8, Page 998-1009, December 2025.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao   +5 more
wiley   +1 more source

Neovessel as first manifestation of relapse of associated multifocal choroiditis and MEWDS

open access: yesInternational Journal of Retina and Vitreous, 2019
Purpose To report a case of multifocal choroiditis (MC) that has relapsed as choroidal neovascularization in the contralateral eye followed by a mixed aspect of multiple evanescent white dot syndrome (MEWDS) and MC.
Eduardo Morizot, Camila Schiavo Froner
doaj   +1 more source

Active surveillance of choroidal neovascularisation in children: incidence, aetiology and management findings from a national study in the UK [PDF]

open access: yes, 2018
BACKGROUND/AIMS: To determine the UK incidence, demographics, aetiology, management and visual outcome for children developing choroidal neovascularisation (CNV).
Abbouda, A   +5 more
core  

Is Asthma Related to Choroidal Neovascularization?

open access: yesPLoS ONE, 2012
Age-related degeneration (AMD) and asthma are both diseases that are related to the activation of the complement system. The association between AMD and asthma has been debated in previous studies. The authors investigated the relationship between AMD and asthma systemically.The epidemiological study showed that asthma was related to choroidal ...
Yaoyao Sun   +8 more
openaire   +4 more sources

Aqueous humour concentrations of HB‐EGF, EGF and VEGF‐A and axial length in humans

open access: yesActa Ophthalmologica, Volume 103, Issue 8, Page 919-928, December 2025.
Abstract Purpose To investigate relationships between the intraocular concentrations of heparin‐binding epidermal growth factor (HB‐EGF), epidermal growth factor (EGF) and vascular endothelial growth factor A (VEGF‐A) in dependence on axial length in humans. Design Clinical interventional cohort study.
Wen‐Da Zhou   +8 more
wiley   +1 more source

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