Results 101 to 110 of about 38,655 (291)

A simple optical coherence tomography quantification method for choroidal neovascularization [PDF]

open access: yes, 2015
Purpose: Therapeutic efficacy is routinely assessed by measurement of lesion size using flatmounted choroids and confocal microscopy in the laser-induced choroidal neovascularization (L-CNV) rodent model.
Boulton, Michael E.   +6 more
core   +1 more source

Automated segmentation and extraction of posterior eye segment using OCT scans [PDF]

open access: yesarXiv, 2021
This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT) scans. The proposed method works in two phases.
arxiv  

Experimental and Computational Insights into the Structural Dynamics of the Fc Fragment of IgG1 Subtype from Biosimilar VEGF‐Trap

open access: yesSmall Structures, EarlyView.
The constant fragment (Fc) of the immunoglobulin G1 (IgG1) subtype is a widely used scaffold for designing advanced therapeutics. Herein, together with the integration of experimental and computational techniques, this study reveals the structural dynamics of the N‐glycan‐bound Fc fragment of IgG1 from VEGF‐Trap, providing a new insight into enhancing ...
Ebru Destan   +11 more
wiley   +1 more source

Evaluating the Therapeutic Potential of Superoxide Dismutase in a Rat Model of Wet Age‐Related Macular Degeneration

open access: yesFASEB BioAdvances, EarlyView.
Oral Superoxide Dismutase Therapy Mitigates Choroidal Neovascularization in a Laser‐Induced Rat Model of Wet Age‐Related Macular Degeneration. Oral Administration of GF103, a Superoxide Dismutase From Bacillus amyloliquefaciens, Reduces Choroidal Neovascularization (CNV) in a Laser‐Induced CNV Rat Model.
Hyun Chul Jeong   +4 more
wiley   +1 more source

Chorioretinal Coloboma Complications: Retinal Detachment and Choroidal Neovascular Membrane [PDF]

open access: yes, 2017
PURPOSE: To report the chorioretinal coloboma, and its association with increased risk of retinal detachment (RD) and choroidal neovascularization (CNV).
Abbey, Ashkan M.   +5 more
core   +3 more sources

Multiple choroidal osteomas in a boy – a rare presentation: a case report

open access: yesJournal of Medical Case Reports, 2019
Background Choroidal osteoma is rare clinical entity of unknown etiology, characterized by formation of mature cancellous bone within the choroid. It typically affects young females, with no racial predilection.
Arup Deuri   +3 more
doaj   +1 more source

Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra‐wide‐field optical coherence tomography angiography

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra‐wide‐field optical coherence tomography angiography (UWF‐OCTA). Methods HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited.
Qing Zhao   +5 more
wiley   +1 more source

Choroidal ischemia drives macular neovascularization in persistent placoid maculopathy

open access: yesAmerican Journal of Ophthalmology Case Reports, 2022
Purpose: To describe a case of persistent placoid maculopathy (PPM) complicated by macular neovascularization (MNV) that developed in areas of prior choroidal ischemia as illustrated with sequential optical coherence tomography angiography. Observations:
Meira Fogel Levin   +2 more
doaj  

Molecular and cellular mechanisms underlying gyrate atrophy: Why is the retina primarily affected?

open access: yesActa Ophthalmologica, EarlyView.
Abstract Gyrate atrophy of the choroid and retina (GACR; OMIM #258870) is a rare early‐onset autosomal recessive disorder, caused by bi‐allelic pathogenic variants in the gene coding for ornithine aminotransferase (OAT) resulting in hyperornithinaemia.
Mark J. N. Buijs   +12 more
wiley   +1 more source

Long-term follow-up of myopic choroidal neovascularization treated with ranibizumab [PDF]

open access: yes, 2011
PURPOSE: To evaluate the long-term safety and efficacy of intravitreal ranibizumab in the treatment of myopic choroidal neovascularization (CNV). METHODS: Three-year retrospective, nonrandomized, interventional case series.
Cachulo, ML   +6 more
core   +1 more source

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