Results 11 to 20 of about 40,563 (261)

Mass spectrometry in ocular drug research

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo   +6 more
wiley   +1 more source

MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]

open access: yes, 2012
Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
A Swaroop   +52 more
core   +12 more sources

Toxoplasma Retinochoroiditis with Chorioretinal Neovascularization in a Young Patient

open access: yesCase Reports in Ophthalmology, 2021
We present a pediatric case to highlight the clinical appearance and management of choroidal neovascularization in the setting of active toxoplasma retinochoroiditis (TRC).
Nikhila S. Khandwala   +2 more
doaj   +1 more source

Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]

open access: yes, 2017
Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson   +8 more
core   +1 more source

Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization.

open access: yesPLoS ONE, 2017
This study investigated the potential role of sirtuin 1 in Müller glial cells in choroidal neovascularization. In the in vitro study, primary Müller glial cells were cultured and treated with resveratrol, a sirtuin 1 activator.
Tomoka Ishida   +6 more
doaj   +1 more source

5α-Hydroxycostic acid inhibits choroidal neovascularization in rats through a dual signalling pathway mediated by VEGF and angiopoietin 2

open access: yesMolecular Medicine, 2023
Background 5α-Hydroxycostic acid is a eudemane sesquiterpene that is isolated from the natural plant, Laggera alata. It exerts anti-inflammatory and anti-angiogenic effects on human breast cancer cells, but its role and underlying mechanism in choroidal ...
Wulong Lei   +6 more
doaj   +1 more source

Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]

open access: yes, 2017
Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria   +5 more
core   +3 more sources

Choroidal Neovascularization

open access: yesOphthalmology, 1986
Choroidal neovascularization is now considered to be a most important feature in the pathogenesis and treatment of a number of chorioretinal disorders. Since the recognition of its importance, choroidal neovascularization has been described in clinical and pathologic studies of a variety of different ophthalmologic conditions.
W R, Green, D J, Wilson
openaire   +2 more sources

Unaffected fellow eye neovascularization in patients with type 3 neovascularization: Incidence and risk factors.

open access: yesPLoS ONE, 2021
PurposeTo evaluate the incidence and risk factors of neovascularization in unaffected fellow eyes of patients diagnosed with type 3 neovascularization in Korea.MethodsThis retrospective study included 93 unaffected fellow eyes of 93 patients diagnosed ...
Jae Hyuck Kwak   +5 more
doaj   +1 more source

Soluble Epoxide Hydrolase Inhibition for Ocular Diseases: Vision for the Future [PDF]

open access: yes, 2019
Ocular diseases cause visual impairment and blindness, imposing a devastating impact on quality of life and a substantial societal economic burden. Many such diseases lack universally effective pharmacotherapies.
Corson, Timothy W., Park, Bomina
core   +1 more source

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