Results 11 to 20 of about 38,655 (291)
Ferrochelatase is a therapeutic target for ocular neovascularization [PDF]
EMBO Molecular Medicine, 2017 Ocular neovascularization underlies major blinding eye diseases such as “wet” age‐related macular degeneration (AMD). Despite the successes of treatments targeting the vascular endothelial growth factor (VEGF) pathway, resistant and refractory patient ...
Halesha D Basavarajappa +16 more
doaj +2 more sources
Influence of plasminogen activator inhibitor type 1 on choroidal neovascularization [PDF]
, 2001 peer reviewedHigh levels of the plasminogen activators, but also their inhibitor, plasminogen activator inhibitor 1 (PAI-1), have been documented in neovascularization of severe ocular pathologies such as diabetic retinopathy or age-related macular ...
Vincent Lambert +9 more
openalex +4 more sources
Mass spectrometry in ocular drug research
Mass Spectrometry Reviews, EarlyView., 2023 Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo +6 more
wiley +1 more source
Optical Coherence Tomographic Angiography Imaging in Age-Related Macular Degeneration. [PDF]
, 2017 Optical coherence tomographic angiography (OCTA) is emerging as a rapid, noninvasive imaging modality that can provide detailed structural and flow information on retinal and choroidal vasculature.
Desai, Ria +5 more
core +3 more sources
PLoS ONE, 2021 PurposeTo evaluate the incidence and risk factors of neovascularization in unaffected fellow eyes of patients diagnosed with type 3 neovascularization in Korea.MethodsThis retrospective study included 93 unaffected fellow eyes of 93 patients diagnosed ...
Jae Hyuck Kwak +5 more
doaj +1 more source
Gyrate Atrophy and Choroidal Neovascularization [PDF]
Archives of Ophthalmology, 1996 Item does not contain ...
Marano, F. +3 more
openaire +4 more sources
MFGE8 does not influence chorio-retinal homeostasis or choroidal neovascularization in vivo [PDF]
, 2012 Purpose: Milk fat globule-epidermal growth factor-factor VIII (MFGE8) is necessary for diurnal outer segment phagocytosis and promotes VEGF-dependent neovascularization.
A Swaroop +52 more
core +7 more sources
Potential role of sirtuin 1 in Müller glial cells in mice choroidal neovascularization.
PLoS ONE, 2017 This study investigated the potential role of sirtuin 1 in Müller glial cells in choroidal neovascularization. In the in vitro study, primary Müller glial cells were cultured and treated with resveratrol, a sirtuin 1 activator.
Tomoka Ishida +6 more
doaj +1 more source
Ophthalmology, 1986 Choroidal neovascularization is now considered to be a most important feature in the pathogenesis and treatment of a number of chorioretinal disorders. Since the recognition of its importance, choroidal neovascularization has been described in clinical and pathologic studies of a variety of different ophthalmologic conditions.
W R, Green, D J, Wilson
openaire +2 more sources
Morphologic Criteria of Lesion Activity in Neovascular Age-Related Macular Degeneration: A Consensus Article [PDF]
, 2017 Intravitreal antivascular endothelial growth factor drugs represent the current standard of care for neovascular age-related macular degeneration (nAMD).
Elena Gusson +8 more
core +1 more source