Choroidal neovascularization characterizes wet age-related macular degeneration. Choroidal neovascularization formation involves a primarily angiogenic process that is combined with both inflammation and proteolysis.
Bridget Martinez, Philip V Peplow
doaj +2 more sources
Inflammatory choroidal neovascular membranes are challenging to diagnose and manage. A number of uveitic entities may be complicated by the development of choroidal neovascularization leading to a decrease in central visual acuity.
Aniruddha Agarwal+8 more
doaj +2 more sources
Influence of Plasminogen Activator Inhibitor Type 1 on Choroidal Neovascularization [PDF]
peer reviewedHigh levels of the plasminogen activators, but also their inhibitor, plasminogen activator inhibitor 1 (PAI-1), have been documented in neovascularization of severe ocular pathologies such as diabetic retinopathy or age-related macular ...
Bajou, Khalid+9 more
core +3 more sources
Spectral domain-optical coherence tomography retinal biomarkers in choroidal neovascularization of multifocal choroiditis, myopic choroidal neovascularization, and idiopathic choroidal neovascularization [PDF]
Objective To use optical coherence tomography (OCT) to compare retinal biomarkers of choroidal neovascularization (CNV) secondary to multifocal choroiditis (MFC), myopic choroidal neovascularization (mCNV), and idiopathic choroidal neovascularization ...
Rui Gao+4 more
doaj +4 more sources
Indocyanine green-mediated photothrombosis combined with intravitreal triamcinolone for the treatment of choroidal neovascularization in serpiginous choroiditis [PDF]
Purpose To report a case of peripapillary choroidal neovascularization (CNV) complicating serpiginous choroiditis that was treated by a single indocyanine green (ICG)mediated photothrombosis session combined to intravitreous triamcinolone acetonide ( TA)
A Kamal+12 more
core +3 more sources
Diagnostic Challenges in Inflammatory Choroidal Neovascularization [PDF]
Inflammation plays a key role in the induction of choroidal neovascularization (CNV). Inflammatory choroidal neovascularization (iCNV) is a severe but uncommon complication of both infectious and non-infectious uveitides.
Izabella Karska-Basta+6 more
doaj +2 more sources
Rac1 overexpression promotes Treg-derived cytokines to mediate choroidal neovascularization in wet age-related macular degeneration [PDF]
Age-related macular degeneration (AMD), particularly the wet form characterized by choroidal neovascularization, is a leading cause of vision loss. Dysregulation of regulatory T cells (Tregs), key modulators of inflammatory responses, may contribute to ...
Juanjuan Li+3 more
doaj +2 more sources
Inflammatory Choroidal Neovascularization [PDF]
Inflammatory choroidal neovascularization (iCNV) is an uncommon complication of uveitis resulting from direct involvement of the retinal pigment epithelium (RPE)-Bruch’s membrane complex by inflamm...
K. Bailey Freund+7 more
openaire +5 more sources
CD11c+ macrophages are proangiogenic and necessary for experimental choroidal neovascularization
Patients with neovascular AMD (nAMD) suffer vision loss from destructive angiogenesis, termed choroidal neovascularization (CNV). Macrophages are found in CNV lesions from patients with nAMD.
Steven Droho+4 more
semanticscholar +1 more source
This study aimed to determine the efficacy of a multimodal deep learning (DL) model using optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) images for the assessment of choroidal neovascularization (CNV) in ...
Kai Jin+9 more
semanticscholar +1 more source