Results 41 to 50 of about 40,563 (261)

Progressive Massive Choroidal Neovascularization, an Aggressive Phenotype: Case Report

Case Reports in Ophthalmology, 2022
We report 2 cases of an aggressive choroidal neovascularization phenotype. A 77-year-old hypertensive woman, with a 4-year history of visual loss in her left eye, due to vitreous hemorrhage associated with a dome-shaped mass lesion underwent pars plana ...
Renata García-Franco, Marlon García-Roa, Roberto Cárdenas-Almagro, Diego Valera-Cornejo, Sergio E. Hernández-Da Mota   +4 more
doaj   +1 more source

A simple optical coherence tomography quantification method for choroidal neovascularization [PDF]

, 2015
Purpose: Therapeutic efficacy is routinely assessed by measurement of lesion size using flatmounted choroids and confocal microscopy in the laser-induced choroidal neovascularization (L-CNV) rodent model.
Boulton, Michael E., Corson, Timothy W., Grant, Maria B., O'Hare, Michael N., Qi, Xiaoping, Quigley, Judith, Sulaiman, Rania S.   +6 more
core   +1 more source

In Vivo Photoacoustic Imaging of Anterior Ocular Vasculature: A Random Sample Consensus Approach [PDF]

, 2019
Visualizing ocular vasculature is important in clinical ophthalmology because ocular circulation abnormalities are early signs of ocular diseases. Photoacoustic microscopy (PAM) images the ocular vasculature without using exogenous contrast agents ...
Jeon, S., Kim, C., Kim, J., Kim, J.H., Kim, J.H., Lee, B.J., Managuli, R., Song, H.B.   +7 more
core   +1 more source

Bilateral Multifocal Choroidal Osteoma with Choroidal Neovascularization [PDF]

Case Reports in Ophthalmological Medicine, 2015
Choroidal osteoma has been reported to be unilateral in approximately 80% of cases diagnosed with this condition. Herein we report the clinical characteristics and multimodal imaging findings in a rare case of bilateral multifocal choroidal osteoma. A 32-year-old female presented with decreased visual acuity (VA) in the right eye (20/100), though she ...
Mousavi Mirnaghi, Saadat Targhi Ali, Hosseini SeyedehMaryam, Shoeibi Nasser   +3 more
openaire   +4 more sources

Ferrochelatase is a therapeutic target for ocular neovascularization

EMBO Molecular Medicine, 2017
Ocular neovascularization underlies major blinding eye diseases such as “wet” age‐related macular degeneration (AMD). Despite the successes of treatments targeting the vascular endothelial growth factor (VEGF) pathway, resistant and refractory patient ...
Halesha D Basavarajappa, Rania S Sulaiman, Xiaoping Qi, Trupti Shetty, Sardar Sheik Pran Babu, Kamakshi L Sishtla, Bit Lee, Judith Quigley, Sameerah Alkhairy, Christian M Briggs, Kamna Gupta, Buyun Tang, Mehdi Shadmand, Maria B Grant, Michael E Boulton, Seung‐Yong Seo, Timothy W Corson   +16 more
doaj   +1 more source

Choroidal juxtapapillary neovascularization regression in multiple evanescent white dot syndrome by optical coherence tomography angiography: a case report

Journal of Medical Case Reports, 2019
Background Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur.
Maria Cristina Savastano, Marco Rispoli, Bruno Lumbroso   +2 more
doaj   +1 more source

Choroidal excavation in choroidal osteoma complicated by choroidal neovascularization [PDF]

Eye, 2017
PurposeTo describe multimodal imaging features of choroidal osteoma (CO) complicated by choroidal neovascularization (CNV) and focal choroidal excavation (FCE).MethodsPatients presenting with CO and CNV between January and October 2016 were considered for this study. Diagnosis of CO was confirmed by ultrasound examination.
Pierro, L., Marchese, A., Gagliardi, M., Introini, U., Battaglia Parodi, M., Bandello, F., Casalino, G.   +6 more
openaire   +3 more sources

Continuous Suppression of Pathological Retinal and Choroidal Neovascularization in Cynomolgus Monkeys via Noninvasive Ophthalmic Delivery of a Novel Anti‐VEGFA Nanobody and Proprietary Penetratin Analog Formulation

Advanced Science, EarlyView.
Pathological retinal/choroidal neovascularization drives vision loss in DR and AMD. Current anti‐VEGF injections, while effective, require invasive, frequent administration. Pene/LQ015, is developed a novel topical anti‐VEGFA nanobody formulation achieving therapeutic intraocular levels through penetratin analog‐enhanced delivery.
Chong Chen, Min Zhu, Xingyan Fan, Kangjia Lv, Kuan Jiang, Yuchen Zhang, Haoliang Zhang, Xinming Qi, Benjamin TK Lee, Yakun Wan, Gang Wei, Kun Liu, Xun Xu   +12 more
wiley   +1 more source

Biomimetic Thalidomide Nanoparticles: Targeted and Sustained Therapeutic Strategy for Oxygen‐Induced Retinopathy

Aggregate, EarlyView.
Magnesium acetyl taurate and thalidomide co‐assembled nanoparticles (MT NPs) are prepared via Super‐stable Pure Nanomedicine Formulation Technology (SPFT), and the NPs are further coated with transferrin‐modified cell membrane vesicles to construct Tfm@MT nanomedicine for oxygen‐induced retinopathy treatment.
Mengdie Li, Shundong Cai, Jinfa Ye, Lang Ke, Guanxiong Yang, Shaopan Wang, Cuiting Chen, Peixin Cai, Hui Liu, Xingyuan Wei, Songyi Wang, Yun Han, Shilong Shao, Min Su, Gang Liu, Chengchao Chu   +15 more
wiley   +1 more source

Dataset of plasma and aqueous humor cytokine profiles in patients with exudative age related macular degeneration and polypoidal choroidal vasculopathy

Data in Brief, 2018
In this report the data was obtained from a prospective case-control study with a sample size of sixteen patients with exudative age related macular degeneration (AMD) due to choroidal neovascularization (CNV) and eighteen patients with polypoidal ...
Praveen Kumar Balne, Rupesh Agrawal, Veonice Bijin AU, Bernett Lee, Arkasubhra Ghosh, Swaminathan Sethu, Mukesh Agrawal, Raja Narayanan, John Connolly   +8 more
doaj   +1 more source