Results 41 to 50 of about 101,649 (294)
Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction
Frontiers in Pharmacology, 2019 Many conditions affecting the heart, brain, and even the eyes have their origins in blood vessel pathology, underscoring the role of vascular regulation.
N. Yeo, E. Chan, C. Cheung
semanticscholar +1 more source
Journal of Medical Case Reports, 2019 Background Multiple evanescent white dot syndrome most often resolves spontaneously without complications; however, choroidal neovascularization can sometimes occur.
Maria Cristina Savastano +2 more
doaj +1 more source
Automatic Segmentation and Visualization of Choroid in OCT with Knowledge Infused Deep Learning [PDF]
, 2020 The choroid provides oxygen and nourishment to the outer retina thus is related to the pathology of various ocular diseases. Optical coherence tomography (OCT) is advantageous in visualizing and quantifying the choroid in vivo. (1) The lower boundary of the choroid (choroid-sclera interface) in OCT is fuzzy, which makes the automatic segmentation ...
arxiv +1 more source
Waveform analysis of human retinal and choroidal blood flow with laser Doppler holography [PDF]
, 2021 Laser Doppler holography was introduced as a full-field imaging technique to measure blood flow in the retina and choroid with an as yet unrivaled temporal resolution. We here investigate separating the different contributions to the power Doppler signal in order to isolate the flow waveforms of vessels in the posterior pole of the human eye.
arxiv +1 more source
Progression of subclinical choroidal neovascularization in age-related macular degeneration
PLoS ONE, 2019 Purpose To use optical coherence tomography angiography (OCTA) to study longitudinal subclinical choroidal neovascularization (CNV) changes and their correlation with progression to exudation in age-related macular degeneration (AMD).
Michael J. Heiferman, A. Fawzi
semanticscholar +1 more source
Ferrochelatase is a therapeutic target for ocular neovascularization
EMBO Molecular Medicine, 2017 Ocular neovascularization underlies major blinding eye diseases such as “wet” age‐related macular degeneration (AMD). Despite the successes of treatments targeting the vascular endothelial growth factor (VEGF) pathway, resistant and refractory patient ...
Halesha D Basavarajappa +16 more
doaj +1 more source
Multi-Scale Convolutional Neural Network for Automated AMD Classification using Retinal OCT Images [PDF]
arXiv, 2021 Age-related macular degeneration (AMD) is the most common cause of blindness in developed countries, especially in people over 60 years of age. The workload of specialists and the healthcare system in this field has increased in recent years mainly due to the prevalence of population aging worldwide and the chronic nature of AMD. Recent developments in
arxiv
Animal Models and Experimental Medicine, EarlyView.The present study investigates the role of the NLRP3 inflammasome in the chronicity of ocular inflammation in uveitis using the experimental autoimmune uveitis (EAU) model. Whole eyes collected from EAU mice, 12 weeks post induction, were sectioned and subjected to immunohistochemistry. The confocal images from these sections were then assessed for the
Avik Shome +3 more
wiley +1 more source
Nature Communications, 2019 Choroidal neovascularization (CNV) is a major cause of visual impairment in patients suffering from wet age-related macular degeneration (AMD), particularly when refractory to intraocular anti-VEGF injections.
Min Zhao +19 more
semanticscholar +1 more source
Diverse roles of macrophages in intraocular neovascular diseases: a review [PDF]
International Journal of Ophthalmology, 2017 Macrophages are involved in angiogenesis, and might also contribute to the pathogenesis of intraocular neovascular diseases. Recent studies indicated that macrophages exert different functions in the process of intraocular neovascularization, and the ...
Ye-Di Zhou +5 more
doaj +1 more source