Case Reports in Ophthalmological Medicine, 2015 To date, choroidal blood flow reduction in highly myopic eyes appears to be related to the development of choroidal neovascularization secondary to local reduction of arterial flow.
Massimiliano Farina +2 more
doaj +1 more source
Progressive Massive Choroidal Neovascularization, an Aggressive Phenotype: Case Report
Case Reports in Ophthalmology, 2022 We report 2 cases of an aggressive choroidal neovascularization phenotype. A 77-year-old hypertensive woman, with a 4-year history of visual loss in her left eye, due to vitreous hemorrhage associated with a dome-shaped mass lesion underwent pars plana ...
Renata García-Franco +4 more
doaj +1 more source
Choroidal Neovascularization: Mechanisms of Endothelial Dysfunction
Frontiers in Pharmacology, 2019 Many conditions affecting the heart, brain, and even the eyes have their origins in blood vessel pathology, underscoring the role of vascular regulation.
N. Yeo, E. Chan, C. Cheung
semanticscholar +1 more source
Management of Uveitis-Related Choroidal Neovascularization: From the Pathogenesis to the Therapy
Journal of Ophthalmology, 2014 Inflammatory choroidal neovascularization is a severe but uncommon complication of uveitis, more frequent in posterior uveitis such as punctate inner choroidopathy, multifocal choroiditis, serpiginous choroiditis, and Vogt-Koyanagi-Harada syndrome.
Enzo D’Ambrosio +2 more
doaj +1 more source
CHOROIDAL NEOVASCULARIZATION ASSOCIATED WITH BEST’S DISEASE
Vision Pan-America, 2016 Best’s Disease is a macular dystrophy characterized by a lipofuscin accumulation on the retinal pigment epithelium. Five stages have been described based on fundus examination, including choroidal neovascularization.
Cristina Nieto Gómez +5 more
doaj +1 more source
Delta-like 4 inhibits choroidal neovascularization despite opposing effects on vascular endothelium and macrophages.: DLL4's opposing effects in choroidal neovascularization [PDF]
, 2012 International audienceInflammatory neovascularization, such as choroidal neovascularization (CNV), occur in the presence of Notch expressing macrophages. DLL4s anti-angiogenic effect on endothelial cells (EC) has been widely recognized, but its influence
Calippe, Bertrand +16 more
core +4 more sources
Intravenous treatment of choroidal neovascularization by photo-targeted nanoparticles
Nature Communications, 2019 Choroidal neovascularization (CNV) is the major cause of vision loss in wet age-related macular degeneration (AMD). Current therapies require repeated intravitreal injections, which are painful and can cause infection, bleeding, and retinal detachment ...
Yanfei Wang +7 more
semanticscholar +1 more source
In Vivo Photoacoustic Imaging of Anterior Ocular Vasculature: A Random Sample Consensus Approach [PDF]
, 2019 Visualizing ocular vasculature is important in clinical ophthalmology because ocular circulation abnormalities are early signs of ocular diseases. Photoacoustic microscopy (PAM) images the ocular vasculature without using exogenous contrast agents ...
Jeon, S. +7 more
core +1 more source
A simple optical coherence tomography quantification method for choroidal neovascularization [PDF]
, 2015 Purpose: Therapeutic efficacy is routinely assessed by measurement of lesion size using flatmounted choroids and confocal microscopy in the laser-induced choroidal neovascularization (L-CNV) rodent model.
Boulton, Michael E. +6 more
core +1 more source
Ferrochelatase is a therapeutic target for ocular neovascularization
EMBO Molecular Medicine, 2017 Ocular neovascularization underlies major blinding eye diseases such as “wet” age‐related macular degeneration (AMD). Despite the successes of treatments targeting the vascular endothelial growth factor (VEGF) pathway, resistant and refractory patient ...
Halesha D Basavarajappa +16 more
doaj +1 more source