Results 81 to 90 of about 38,223 (243)
Small Structures, EarlyView.The constant fragment (Fc) of the immunoglobulin G1 (IgG1) subtype is a widely used scaffold for designing advanced therapeutics. Herein, together with the integration of experimental and computational techniques, this study reveals the structural dynamics of the N‐glycan‐bound Fc fragment of IgG1 from VEGF‐Trap, providing a new insight into enhancing ...
Ebru Destan +11 more
wiley +1 more source
Kaohsiung Journal of Medical Sciences, 2009 Choroidal neovascularization is a major cause of visual loss in age-related macular degeneration. It is also a potential vision-threatening complication of pathologic myopia, uveitis, traumatic choroidal rupture and, rarely, endophthalmitis.
Shwu-Jiuan Sheu
doaj +1 more source
Generative Adversarial Networks Synthesize Realistic OCT Images of the Retina [PDF]
arXiv, 2019 We report, to our knowledge, the first end-to-end application of Generative Adversarial Networks (GANs) towards the synthesis of Optical Coherence Tomography (OCT) images of the retina. Generative models have gained recent attention for the increasingly realistic images they can synthesize, given a sampling of a data type.
arxiv
A simple optical coherence tomography quantification method for choroidal neovascularization [PDF]
, 2015 Purpose: Therapeutic efficacy is routinely assessed by measurement of lesion size using flatmounted choroids and confocal microscopy in the laser-induced choroidal neovascularization (L-CNV) rodent model.
Boulton, Michael E. +6 more
core +1 more source
FASEB BioAdvances, EarlyView.Oral Superoxide Dismutase Therapy Mitigates Choroidal Neovascularization in a Laser‐Induced Rat Model of Wet Age‐Related Macular Degeneration. Oral Administration of GF103, a Superoxide Dismutase From Bacillus amyloliquefaciens, Reduces Choroidal Neovascularization (CNV) in a Laser‐Induced CNV Rat Model.
Hyun Chul Jeong +4 more
wiley +1 more source
American Journal of Ophthalmology Case Reports, 2021 Purpose: To describe the multimodal imaging findings and treatment outcomes in choroidal neovascularization secondary to Choroideremia. Observations: A 13-year-old male presented with reduced visual acuity in the left eye. He gave a history of nyctalopia.
Ratnesh Ranjan +5 more
doaj
Choroidal neovascularization secondary to Best’s vitelliform macular dystrophy in two siblings of a Malay family [PDF]
, 2014 Best’s vitelliform macular dystrophy complicated with choroidal neovascularization is rare in children. We report three children from a Malay family of five siblings with Best’s vitelliform macular dystrophy, in which two of them subsequently developed ...
Embong, Zunaina +4 more
core
Anti-vascular Endothelial Growth Factor for Choroidal Neovascularization Associated with Toxoplasmosis: A Case Series [PDF]
, 2015 The purpose of the study was to evaluate the efficacy and safety of intravitreal anti-vascular endothelial growth factor (anti-VEGF) in treatment of choroidal neovascularization (CNV) secondary to toxoplasmic retinochoroiditis in five patients.
Ahmadi, Mostafa. +4 more
core +1 more source
Aging Cell, Volume 24, Issue 4, April 2025.circSIRT2 inhibited SRF by binding miR‐542‐3p, which stimulated the VASH1 expression and subsequently suppressed EndMT. The circSIRT2/miR‐542‐3p/VASH1 axis may serve as a promising therapeutic target for SRF in nAMD. Abstract Neovascular age‐related macular degeneration (nAMD), characterized by choroidal neovascularization (CNV), is one of the leading ...
Min Zhang +8 more
wiley +1 more source
Automated segmentation and extraction of posterior eye segment using OCT scans [PDF]
arXiv, 2021 This paper proposes an automated method for the segmentation and extraction of the posterior segment of the human eye, including the vitreous, retina, choroid, and sclera compartments, using multi-vendor optical coherence tomography (OCT) scans. The proposed method works in two phases.
arxiv