Results 81 to 90 of about 24,806 (241)

Adalimumab Monotherapy or Combination Therapy With Methotrexate in Paediatric Uveitis: Data From the AIDA Network Uveitis Registry

open access: yesClinical &Experimental Ophthalmology, EarlyView.
ABSTRACT Background The study objective was to compare the effectiveness of adalimumab (ADA) in monotherapy and in combination with methotrexate (MTX) for paediatric noninfectious uveitis (NIU). Methods Registry‐based observational study. Children receiving ADA for active uveitis were divided into the ADA monotherapy group (group 1) and the ADA plus ...
Carla Gaggiano   +40 more
wiley   +1 more source

Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis

open access: yesEBioMedicine, 2016
Neovascular eye diseases including retinopathy of prematurity, diabetic retinopathy and age-related-macular-degeneration are major causes of blindness.
Yan Gong   +14 more
doaj   +1 more source

Deep learning architecture LightOCT for diagnostic decision support using optical coherence tomography images of biological samples [PDF]

open access: yesarXiv, 2018
Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in textural and geometric features of the OCT images, which are used by human expertise to interpret and triage. However,
arxiv  

Influence of scleral thickness on photodynamic therapy outcomes in central serous chorioretinopathy

open access: yesActa Ophthalmologica, Volume 103, Issue 3, Page e165-e175, May 2025.
Abstract Purpose To test the prognostic role of anterior scleral substantia propria (ASSP) thickness in predicting the 3‐month response after half‐dose photodynamic therapy (PDT) in central serous chorioretinopathy (CSCR) and to assess its clinical relevance of ASSP in different CSCR phenotypes.
Paolo Forte   +11 more
wiley   +1 more source

Peripapillary Choroidal Neovascularization Associated with Optic Nerve Head Drusen Treated with Anti-VEGF Agents

open access: yesCase Reports in Ophthalmology, 2015
Optic nerve head drusen can be associated with peripapillary choroidal neovascularization, in both the pediatric and adult population. These membranes can involve the macula, causing significant visual loss.
Norman A. Saffra, Benjamin J. Reinherz
doaj   +1 more source

Natural products targeting tumour angiogenesis

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 10, Page 2094-2136, May 2025.
Abstract Tumour angiogenesis is the formation of new blood vessels to support the growth of a tumour. This process is critical for tumour progression and metastasis, making it an attractive approach to cancer therapy. Natural products derived from plants, animals or microorganisms exert anti‐angiogenic properties and can be used to inhibit tumour ...
Xiaohua Lu   +2 more
wiley   +1 more source

Neovessel as first manifestation of relapse of associated multifocal choroiditis and MEWDS

open access: yesInternational Journal of Retina and Vitreous, 2019
Purpose To report a case of multifocal choroiditis (MC) that has relapsed as choroidal neovascularization in the contralateral eye followed by a mixed aspect of multiple evanescent white dot syndrome (MEWDS) and MC.
Eduardo Morizot, Camila Schiavo Froner
doaj   +1 more source

Choroidal neovascularization after cryoapplication

open access: yesAlbrecht von Graefes Archiv f�r Klinische und Experimentelle Ophthalmologie, 1981
After sealing peripheral retinal tears in retinal detachment surgery by means of cryoapplications, neovascularization appeared, stemming from the choroidal circulation. This complication was noted in three cases of retinal detachment with tears in an area of latticelike degeneration.
openaire   +4 more sources

Retinal and choroidal angiogenesis: a review of new targets

open access: yesInternational Journal of Retina and Vitreous, 2017
Retinal and choroidal neovascularization are a major cause of significant visual impairment, worldwide. Understanding the various factors involved in the accompanying physiopathology is vital for development of novel treatments, and most important, for ...
Thiago Cabral   +6 more
doaj   +1 more source

Choroidal image analysis for OCT image sequences with applications in systemic health [PDF]

open access: yes
The choroid, a highly vascular layer behind the retina, is an extension of the central nervous system and has parallels with the renal cortex, with blood flow far exceeding that of the brain and kidney. Thus, there has been growing interest of choroidal blood flow reflecting physiological status of systemic disease.
arxiv   +1 more source

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