Results 121 to 130 of about 116,467 (253)
A trust‐region funnel algorithm for gray‐box optimization
Abstract Gray‐box optimization, where parts of optimization problems are represented by algebraic models while others are treated as black‐box models lacking analytic derivatives, remains a challenge. Trust‐region (TR) methods provide a robust framework for gray‐box problems through local reduced models (RMs) for black‐box components, but they are ...
Gul Hameed +4 more
wiley +1 more source
This manuscript focuses on the design and implementation of 2 real‐world screening programs conducted in Ghana and India. These programs were developed to align with the operational realities and resource constraints of each setting, prioritizing approaches that are both sustainable and scalable for long‐term cancer control.
Mary Efua Commeh +15 more
wiley +1 more source
ABSTRACT Tooth extraction is often required before chemoradiotherapy in patients with cancer. We herein report two cases of elderly cancer patients who experienced life‐threatening hemorrhage immediately before scheduled extractions. Case 1 involved a 79‐year‐old man who underwent chemotherapy for malignant lymphoma.
Sumitaka Hagiwara +4 more
wiley +1 more source
ABSTRACT Stem cell therapy is currently undergoing clinical research in China for conditions that are resistant to or incurable by traditional pharmaceutical interventions. Stem cell‐derived extracellular vesicles (EVs) exhibit therapeutic effects similar to those of their parent stem cells, positioning them as an alternative or adjunctive approach to ...
Tao Na +9 more
wiley +1 more source
The concept of the CCHP system (combined cooling, heating and power - combined cooling, heating and electricity generation) is described here. The development of CCHP systems comes from the CHP system (combined heat and power generation), also known as cogeneration.
Stojkov, Marinko +3 more
openaire +3 more sources
ABSTRACT Osteoarthritis (OA) remains without disease‐modifying sssstherapies, in part due to biological heterogeneity and a hostile joint microenvironment that undermines one‐size‐fits‐all interventions. Extracellular vesicles (EVs) play a dual role in OA pathophysiology: endogenous EVs disseminate pro‐inflammatory and catabolic signals that propagate ...
Duc‐Hiep Bach +2 more
wiley +1 more source
Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source
Comparative economical analysis of a small scale trigenerative plant: a case study [PDF]
Canova, Aldo +5 more
core +1 more source
Populism and policy capacity: Evidence from an opposition municipality in Istanbul
Abstract Despite achievements in its conceptual rigor, policy capacity still represents a relatively depoliticized concept that fails to sufficiently consider the ways in which politics plays a role in its creation, mobilization, or decay. This article seeks to contribute to this debate by investigating the impact of populism on policy capacity, the ...
Ebru Ertugal, Faik Gür, İnan Sevinç
wiley +1 more source

