Results 111 to 120 of about 116,467 (253)

Neuronal loss of the pentose phosphate pathway in the living nervous system is causally linked to [NADPH] reduction and elevated oxidative stress

The Journal of Physiology, EarlyView.
Abstract figure legend Using genetically encoded sensors for NADPH and H2O2 in the living Drosophila nervous system, neuron‐specific PPP knockdown is shown to result in reduced neuronal NADPH levels and elevated neuronal H2O2 levels and oxidative stress.
Stephan Müller, Nina Surina, Andrés Köhler‐Solís, Ioannis Nellas, Astrid Fleige, Sebastian Görtz, Stefanie Schirmeier   +6 more
wiley   +1 more source

Predictive Building Energy Management by Means of Mixed‐Integer Optimal Control With Automated Setup

Proceedings in Applied Mathematics and Mechanics, Volume 26, Issue 2, June 2026.
ABSTRACT Today, a significant portion of total final energy consumption can be attributed to heating systems in buildings. Reducing energy consumption and carbon dioxide emissions in this sector is, therefore, crucial to achieving the goals of climate action initiatives worldwide.
Artyom Burda, Philip Lay, Mirco Rode, Martin Grotjahn, Christian Kirches   +4 more
wiley   +1 more source

Management of Primary Refractory Diffuse Large B‐Cell Lymphoma in Patients Unsuitable for CAR T‐Cell Therapy

European Journal of Haematology, Volume 116, Issue 6, Page 771-784, June 2026.
ABSTRACT Primary refractory Diffuse Large B‐Cell Lymphoma is associated with poor outcomes and limited responsiveness to conventional salvage therapies. Although CAR T‐cell therapy represents the standard of care in this setting, a substantial proportion of patients cannot receive it despite meeting disease‐related criteria. In this review, “unsuitable”
Santino Caserta, Enrica Antonia Martino, Mamdouh Skafi, Maria Eugenia Alvaro, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Ernesto Vigna, Fortunato Morabito, Massimo Gentile   +12 more
wiley   +1 more source

Mosunetuzumab plus Pola-CHP compared with Pola-R-CHP in previously untreated DLBCL: final results from a phase 2 study

Blood Advances
: This phase 2 study evaluated mosunetuzumab plus cyclophosphamide, doxorubicin, prednisone, and polatuzumab vedotin (Pola-M-CHP) vs Pola-rituximab (R)-CHP for first-line treatment of diffuse large B-cell lymphoma. Patients were randomized 2:1 to receive
Jason Westin, Tycel J. Phillips, Amitkumar Mehta, Marc S. Hoffmann, Eva Gonzalez-Barca, Catherine Thieblemont, Mariana Bastos-Oreiro, Richard Greil, Sebastian Giebel, Michael C. Wei, Jue Wang, Reinhard Bucher, Jason Sit, Elicia Penuel, Enkhtsetseg Purev, Donald L. Yee, Juan Miguel Bergua-Burgues   +16 more
doaj   +1 more source

An early assessment of national allocation plans for phase 2 of EU emission trading [PDF]

, 2006
No description ...
Betz, Regina, Rogge, Karoline, Schleich, Joachim   +2 more
core   +1 more source

Corn and Switchgrass Derived Sustainable Aviation Fuel Carbon Intensity

GCB Bioenergy, Volume 18, Issue 6, June 2026.
Life cycle inventory details by ecosystem boundaries for the life cycle assessments (LCA) conducted in this study and timeline of primary data used in LCAs. Abbreviations: SOC, soil organic carbon; N2O, nitrous oxide; EtOH, ethanol; SAF, sustainable aviation fuel; GREET, Greenhouse gases, Regulated Emissions, and Energy use in Technologies.
Salvador Ramirez II, Marty Schmer, Virginia L. Jin, Rob Mitchell, Catherine E. Stewart, Daren Redfearn, John Quinn, Maroua Afi   +7 more
wiley   +1 more source

Morphological changes of the choroid plexus in the lateral ventricle across the lifespan: 5551 subjects from fetus to elderly

NeuroImage
Background: The developmental trajectory and aging process of the choroid plexus (ChP) in humans remain largely unexplored, and normative growth standards for ChP across the lifespan are lacking.
Jiaxin Li, Yuxuan Gao, Yunzhi Xu, Weiying Dai, Yueqin Hu, Xue Feng, Dan Wu, Li Zhao   +7 more
doaj   +1 more source

Can we repudiate ontology altogether?

Noûs, Volume 60, Issue 2, Page 264-292, June 2026.
Abstract Ontological nihilists repudiate ontology altogether, maintaining that ontological structure is an unnecessary addition to our theorizing. Recent defenses of the view involve a sophisticated combination of highly expressive but ontologically innocent languages combined with a metaphysics of features—non‐objectual, complete but modifiable states
Christopher J. Masterman
wiley   +1 more source

Single‐Cell Atlas of Subchondral Bone Marrow Lesions Reveals Proteostasis Dysfunction as a Druggable Mechanism for Early Osteoarthritis

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study reveals that abnormal mechanical stress downregulates the expression of HSP70 and impairs proteasome function in osteoarthritic bone cells, leading to misfolded collagen I accumulation and ER stress. When intracellular proteostasis capacity is exceeded, USP19 mediates the secretion of misfolded proteins into the extracellular space ...
Hailun Xu, Ting He, Yu Qian, Jia Li, Bowei Ni, Xiaojie Xu, Huanbo Wang, Peng Wang, Guoqing Cao, Siqi Ying, Guangyu Ding, Rong Wang, Zenghui Gu, Wei Li, Zhentao Man, Houfeng Zheng, Zhaohua Zhu, Zhen Li, Qingjun Meng, Chao Zheng, Liu Yang   +20 more
wiley   +1 more source

Health Coverage for Immigrants in New York: An Update on Policy Developments and Next Steps [PDF]

, 2002
Examines the implementation of a New York State Court of Appeals decision to extend coverage to legal immigrants, and addresses the need for federal financial assistance to help provide health coverage to legal immigrants on the same basis as ...
Deborah Bachrach, Karen Lipson
core