Results 1 to 10 of about 753 (146)

Chromatic Pupillometry Findings in Alzheimer’s Disease [PDF]

Frontiers in Neuroscience, 2020
Intrinsically photosensitive melanopsin retinal ganglion cells (mRGCs) are crucial for non-image forming functions of the eye, including the photoentrainment of circadian rhythms and the regulation of the pupillary light reflex (PLR).
Martina Romagnoli, Michelangelo Stanzani Maserati, Maddalena De Matteis, Sabina Capellari, Sabina Capellari, Michele Carbonelli, Giulia Amore, Gaetano Cantalupo, Corrado Zenesini, Rocco Liguori, Rocco Liguori, Alfredo A. Sadun, Valerio Carelli, Valerio Carelli, Jason C. Park, Chiara La Morgia, Chiara La Morgia   +16 more
doaj   +14 more sources

Chromatic pupillometry for evaluating melanopsin retinal ganglion cell function in Alzheimer’s disease and other neurodegenerative disorders: a review [PDF]

Frontiers in Psychology, 2023
The evaluation of pupillary light reflex (PLR) by chromatic pupillometry may provide a unique insight into specific photoreceptor functions. Chromatic pupillometry refers to evaluating PLR to different wavelengths and intensities of light in order to ...
Martina Romagnoli, Giulia Amore, Pietro Avanzini, Valerio Carelli, Valerio Carelli, Chiara La Morgia, Chiara La Morgia   +6 more
doaj   +9 more sources

Chromatic Pupillometry in Children [PDF]

Frontiers in Neurology, 2018
Chromatic pupillometry is a technique that is increasingly used to assess retinal disorders. As age may be one of the various factors which can influence the pupillary light reaction, this study aimed to evaluate the pupil responses to colored light ...
Sylvain V. Crippa, Sylvain V. Crippa, Fatima Pedrosa Domellöf, Aki Kawasaki   +3 more
doaj   +9 more sources

Multimodal investigation of melanopsin retinal ganglion cells in Alzheimer's disease [PDF]

Annals of Clinical and Translational Neurology, 2023
Objective In Alzheimer's disease (AD), the presence of circadian dysfunction is well‐known and may occur early in the disease course. The melanopsin retinal ganglion cell (mRGC) system may play a relevant role in contributing to circadian dysfunction. In
Chiara La Morgia, Micaela Mitolo, Martina Romagnoli, Michelangelo Stanzani Maserati, Stefania Evangelisti, Maddalena De Matteis, Sabina Capellari, Claudio Bianchini, Claudia Testa, Gilles Vandewalle, Aurelia Santoro, Michele Carbonelli, Pietro D'Agati, Marco Filardi, Pietro Avanzini, Piero Barboni, Corrado Zenesini, Flavia Baccari, Rocco Liguori, Caterina Tonon, Raffaele Lodi, Valerio Carelli   +21 more
doaj   +5 more sources

Development of a Smartphone-Based System for Intrinsically Photosensitive Retinal Ganglion Cells Targeted Chromatic Pupillometry [PDF]

Bioengineering
Chromatic Pupillometry, used to assess Pupil Light Reflex (PLR) to a coloured light stimulus, has regained interest since the discovery of melanopsin in the intrinsically photosensitive Retinal Ganglion Cells (ipRGCs).
Ana Isabel Sousa, Carlos Marques-Neves, Pedro Manuel Vieira   +2 more
doaj   +8 more sources

Chromatic Pupillometry Methods for Assessing Photoreceptor Health in Retinal and Optic Nerve Diseases [PDF]

Frontiers in Neurology, 2019
The pupillary light reflex is mediated by melanopsin-containing intrinsically-photosensitive retinal ganglion cells (ipRGCs), which also receive input from rods and cones.
A. V. Rukmini, Dan Milea, Dan Milea, Joshua J. Gooley   +3 more
doaj   +7 more sources

Chromatic pupillometry isolation and evaluation of intrinsically photosensitive retinal ganglion cell-driven pupillary light response in patients with retinitis pigmentosa [PDF]

Frontiers in Human Neuroscience, 2023
PurposeThe pupil light response (PLR) is driven by rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). We aimed to isolate ipRGC-driven pupil responses using chromatic pupillometry and to determine the effect of advanced ...
He Zhao, He Zhao, Hao Wang, Hao Wang, Minfang Zhang, Minfang Zhang, Chuanhuang Weng, Chuanhuang Weng, Yong Liu, Yong Liu, Zhengqin Yin, Zhengqin Yin   +11 more
doaj   +7 more sources

Evaluation of the Glaucomatous Macular Damage by Chromatic Pupillometry [PDF]

Ophthalmology and Therapy, 2023
Introduction This study aimed to examine the performance of binocular chromatic pupillometry for the objective and rapid detection of primary open-angle glaucoma (POAG), and to explore the association between pupillary light response (PLR) features and ...
Yadan Quan, Huiyu Duan, Zongyi Zhan, Yuening Shen, Rui Lin, Tingting Liu, Ting Zhang, Jihong Wu, Jing Huang, Guangtao Zhai, Xuefei Song, Yixiong Zhou, Xinghuai Sun   +12 more
doaj   +4 more sources

Binocular head-mounted chromatic pupillometry can detect structural and functional loss in glaucoma [PDF]

Frontiers in Neuroscience, 2023
AimThe aim of this study is to evaluate the utility of binocular chromatic pupillometry in detecting impaired pupillary light response (PLR) in patients with primary open-angle glaucoma (POAG) and to assess the feasibility of using binocular chromatic ...
Yadan Quan, Yadan Quan, Yadan Quan, Huiyu Duan, Zongyi Zhan, Yuening Shen, Rui Lin, Rui Lin, Rui Lin, Tingting Liu, Tingting Liu, Tingting Liu, Ting Zhang, Ting Zhang, Ting Zhang, Jihong Wu, Jihong Wu, Jihong Wu, Jing Huang, Guangtao Zhai, Xuefei Song, Xuefei Song, Yixiong Zhou, Yixiong Zhou, Xinghuai Sun, Xinghuai Sun, Xinghuai Sun, Xinghuai Sun   +27 more
doaj   +4 more sources

Detailed Evaluation of Chromatic Pupillometry and Full-Field Stimulus Testing to Assess Ultralow Vision in Retinitis Pigmentosa [PDF]

Ophthalmology Science, 2023
Purpose: Novel therapeutic options, such as regenerative medicine and gene therapy, are now emerging as viable treatment options for patients with severe visual impairments, such as retinitis pigmentosa (RP).
Midori Yamamoto, Take Matsuyama, PhD, Tadao Maeda, MD, PhD, Seiji Takagi, MD, PhD, Naohiro Motozawa, MD, PhD, Daiki Sakai, MD, Yasuhiko Hirami, MD, PhD, Akiko Maeda, MD, PhD, Yasuo Kurimoto, MD, PhD, Masayo Takahashi, MD, PhD, Michiko Mandai, MD, PhD   +10 more
doaj   +4 more sources