Chromatic Pupillometry in Isolated Rapid Eye Movement Sleep Behavior Disorder. [PDF]
Mov Disord, 2022 Background: Melanopsin retinal ganglion cell (mRGC)-mediated pupillary light reflex (PLR) abnormalities have been documented in several neurodegenerative disorders including Parkinson's disease.
La Morgia C +13 more
europepmc +12 more sources
Chromatic Pupillometry as a Putative Screening Tool for Heritable Retinal Disease in Rhesus Macaques. [PDF]
Transl Vis Sci Technol, 2023 PurposeNon-human primates (NHPs) are useful models for human retinal disease. Chromatic pupillometry has been proposed as a noninvasive method of identifying inherited retinal diseases (IRDs) in humans; however, standard protocols employ time-consuming ...
Salpeter EM +6 more
europepmc +6 more sources
Unilateral anterior ischemic optic neuropathy: chromatic pupillometry in affected, fellow non-affected and healthy control eyes [PDF]
Frontiers in Neurology, 2013 The intrinsically photosensitive retinal ganglion cells (ipRGCs) express the photopigment melanopsin, which is sensitive to blue light. Previous chromatic pupillometry studies have shown that the post-illumination response is considered an indicator of ...
Kristina eHerbst +8 more
doaj +6 more sources
Retinal neural dysfunction in diabetes revealed with handheld chromatic pupillometry. [PDF]
Clin Exp Ophthalmol, 2022 Abstract Background To evaluate the ability of handheld chromatic pupillometry to reveal and localise retinal neural dysfunction in diabetic patients with and without diabetic retinopathy (DR). Methods This cross‐sectional study included 82 diabetics (DM) and 93 controls (60.4 ± 8.4 years, 44.1% males). DM patients included those without (n = 25, 64.7 ±
Tan TE +10 more
europepmc +5 more sources
Pupillometry evaluation of melanopsin retinal ganglion cell function and sleep-wake activity in pre-symptomatic Alzheimer's disease. [PDF]
PLoS ONE, 2019 BACKGROUND:Melanopsin-expressing retinal ganglion cells (mRGCs), intrinsically photosensitive RGCs, mediate the light-based pupil response and the light entrainment of the body's circadian rhythms through their connection to the pretectal nucleus and ...
Angela J Oh +9 more
doaj +2 more sources
Automatic Detection of Genetic Diseases in Pediatric Age Using Pupillometry [PDF]
IEEE Access, 2020 Inherited retinal diseases cause severe visual deficits in children. They are classified in outer and inner retina diseases, and often cause blindness in childhood.
Ernesto Iadanza +6 more
doaj +4 more sources
The diagnostic significance of pupillary reflex pathways: insights from classical examination and advanced pupillometry [PDF]
Frontiers in NeuroscienceBackground/objectivesThe pupil, a dynamic ocular structure, serves as a critical indicator of neurological and ophthalmological function. This interdisciplinary review explores the anatomical, physiological, and pathological aspects of pupillary reflexes
Łukasz Lisowski +5 more
doaj +2 more sources
陆军军医大学学报, 2023 Objective To study the feasibility and effectiveness of quantitative evaluation of retinal function in blind patients with retinitis pigmentosa (RP) by chromatic pupillometry.
ZHAO He, WANG Hao, WENG Chuanhuang
doaj +2 more sources
Pupil responses to colorfulness are selectively reduced in healthy older adults. [PDF]
Sci Rep, 2023 The alignment between visual pathway signaling and pupil dynamics offers a promising non-invasive method to further illuminate the mechanisms of human color perception.
van Leeuwen JEP +5 more
europepmc +3 more sources
Light-Induced Pupillary Responses in Alzheimer's Disease [PDF]
Frontiers in Neurology, 2019 The impact of Alzheimer's disease (AD) on the pupillary light response (PLR) is controversial, being dependent on the stage of the disease and on the experimental pupillometric protocols.
Pratik S. Chougule +8 more
doaj +3 more sources