Results 11 to 20 of about 31,136 (191)

Types of chromosomal abnormalities caused by chemotherapy cyclophosphamide in mice (Mus musculus L.) [PDF]

open access: yesBasrah Journal of Veterinary Research, 1970
The current study was designed to study the genetic effects of Mus musculus L. on male and female laboratory mice. The study included the following: Cyclophosphamide's effects on chromosomal changes in bone marrow cells and testes, as well as a study of ...
Wasan Moayad Shaker   +1 more
doaj   +1 more source

Depletion or cleavage of cohesin during anaphase differentially affects chromatin structure and segregation

open access: yeseLife, 2022
Chromosome segregation requires both the separation of sister chromatids and the sustained condensation of chromatids during anaphase. In yeast cells, cohesin is not only required for sister chromatid cohesion but also plays a major role determining the ...
Jonay Garcia-Luis   +4 more
doaj   +1 more source

LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion.

open access: yesPLoS Biology, 2012
Successful execution of the meiotic program depends on the timely establishment and removal of sister chromatid cohesion. LAB-1 has been proposed to act in the latter by preventing the premature removal of the meiosis-specific cohesin REC-8 at metaphase ...
Yonatan B Tzur   +7 more
doaj   +1 more source

Evaluation of Sister Chromatid Exchanges and Hypoxanthine guanine phosphoribosyl transferase Gene Mutation Assay in Peripheral Lymphocytes of Workers Exposed to Radiation at Al-Tuwaitha Site

open access: yesThe Iraqi Journal of Veterinary Medicine, 2015
The present study aims at using the biological techniques in a genotoxicity assessment of low doses of radiation in samples of workers in Al-Tuwaitha site due to decommissioning to radioactive contamination as a result of work.
Abdulsahib K. Ali
doaj   +1 more source

Sister Chromatid Cohesion [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2012
During S phase, not only does DNA have to be replicated, but also newly synthesized DNA molecules have to be connected with each other. This sister chromatid cohesion is essential for the biorientation of chromosomes on the mitotic or meiotic spindle, and is thus an essential prerequisite for chromosome segregation.
Peters, J.-M. and Nishiyama, T.
openaire   +2 more sources

Chromosome fragility in Freemartin cattle

open access: yesItalian Journal of Animal Science, 2010
The aim of the present study was to verify chromosome fragility in freemartin cattle using chromosome aberration (CA) and sister chromatid exchange (SCE) tests. A total of eighteen co-twins were investigated.
V. Barbieri   +7 more
doaj   +1 more source

S. cerevisiae Cells Can Grow without the Pds5 Cohesin Subunit

open access: yesmBio, 2022
During DNA replication, the newly created sister chromatids are held together until their separation at anaphase. The cohesin complex is in charge of creating and maintaining sister chromatid cohesion (SCC) in all eukaryotes.
Karan Choudhary   +6 more
doaj   +1 more source

Effect of borax on immune cell proliferation and sister chromatid exchange in human chromosomes

open access: yesJournal of Occupational Medicine and Toxicology, 2009
Background Borax is used as a food additive. It becomes toxic when accumulated in the body. It causes vomiting, fatigue and renal failure. Methods The heparinized blood samples from 40 healthy men were studied for the impact of borax toxicity on immune ...
Pongsavee Malinee
doaj   +1 more source

The Interplay of Cohesin and the Replisome at Processive and Stressed DNA Replication Forks

open access: yesCells, 2021
The cohesin complex facilitates faithful chromosome segregation by pairing the sister chromatids after DNA replication until mitosis. In addition, cohesin contributes to proficient and error-free DNA replication.
Janne J. M. van Schie, Job de Lange
doaj   +1 more source

Hsp90 Is Essential for Chl1-Mediated Chromosome Segregation and Sister Chromatid Cohesion

open access: yesmSphere, 2018
Recent studies have demonstrated that aberrant sister chromatid cohesion causes genomic instability and hence is responsible for the development of a tumor.
Nidhi Khurana   +4 more
doaj   +1 more source

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