Results 21 to 30 of about 31,136 (191)
Essential roles of BCCIP in mouse embryonic development and structural stability of chromosomes. [PDF]
PLoS Genetics, 2011 BCCIP is a BRCA2- and CDKN1A(p21)-interacting protein that has been implicated in the maintenance of genomic integrity. To understand the in vivo functions of BCCIP, we generated a conditional BCCIP knockdown transgenic mouse model using Cre-LoxP ...
Huimei Lu +7 more
doaj +1 more source
An In Vitro and In Vivo Assessment of the Genotoxic Potential of Maizinol (UP165), a Zea mays Leaf Extract. [PDF]
J Appl ToxicolABSTRACT Benzoxazinoids are secondary metabolites produced in monocotyledons and some dicotyledons from the Acanthaceae, Ranunculaceae, Scrophulariaceae, Plantaginaceae, and Lamiaceae families. Benzoxazinoids are commonly consumed in bread and cereal products that have been ingested for decades, which supports the safe use of benzoxazinoids as food ...
Weston JK, Lynch BS, Akingbasote JA.
europepmc +2 more sources
BMC Genetics, 2002 Background Ciliates employ massive chromatid breakage and de novo telomere formation during generation of the somatic macronucleus. Positions flanking the 81-MAC locus are reproducibly cut.
Doak Thomas G +2 more
doaj +1 more source
A Live-Cell Imaging Approach for Measuring DNA Replication Rates
Cell Reports, 2018 Summary: We describe a simple and direct approach to measure the progression of single DNA replication forks in living cells by monitoring two fluorescently labeled loci downstream of an origin of replication.
Daniel Dovrat +5 more
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Stem Cell Research, 2020 Bloom syndrome is characterized by severe pre- and postnatal growth deficiency, immune abnormalities, sensitivity to sunlight, insulin resistance, and a high risk for many cancers that occur at an early age. The diagnosis is established on characteristic
Vincent Gatinois +7 more
doaj +1 more source
Protocol for High-Throughput Analysis of Sister-Chromatids Contacts
STAR Protocols, 2020 Summary: Sister chromatid interactions are a key step to ensure the successful segregation of sister chromatids after replication. Our knowledge about this phenomenon is mostly based on microscopy approaches, which have some constraints such as ...
Elena Espinosa +2 more
doaj +1 more source
Cohesin without cohesion: a novel role for Pds5 in Saccharomyces cerevisiae. [PDF]
PLoS ONE, 2014 High fidelity chromosome segregation during mitosis requires that cells identify the products of DNA replication during S-phase and then maintain that identity until anaphase onset.
Kevin Tong, Robert V Skibbens
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Cytogenetic Study among Chemical Bombardment Survivors in Shekh Wasan & Balisan Valley Kurdistan Region-Iraq [PDF]
Eurasian Journal of Science and Engineering, 2017 This study was performed randomly on 40 individuals selected within a specific period, between January 2014 to October 2014 in order to a certain whether or not a sample of chemical weapons used on Shekh Wasan & Balisan valley in 16 April 1987, have ...
Hazha Jamal Hidayet +1 more
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Targeted sister chromatid cohesion by Sir2. [PDF]
PLoS Genetics, 2011 The protein complex known as cohesin binds pericentric regions and other sites of eukaryotic genomes to mediate cohesion of sister chromatids. In budding yeast Saccharomyces cerevisiae, cohesin also binds silent chromatin, a repressive chromatin ...
Ching-Shyi Wu +2 more
doaj +1 more source
Genetic evaluation of mesenchymal stem cells by G-banded karyotyping in a Cell Technology Center
Revista Brasileira de Hematologia e Hemoterapia, 2014 OBJECTIVE: To present the initial results of first three years of implementation of a genetic evaluation test for bone marrow-derived mesenchymal stem cells in a Cell Technology Center.METHODS: A retrospective study was carried out of 21 candidates for ...
Tamara Borgonovo +4 more
doaj +1 more source