Results 251 to 260 of about 83,148 (303)

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Integrated promoter-capture Hi-C and Hi-C analysis reveals fine-tuned regulation of the 3D chromatin architecture in colorectal cancer. [PDF]

Front Genet
Saw AK, Madhok A, Bhattacharya A, Nandi S, Galande S.   +4 more
europepmc   +1 more source

Epigenetic Dysregulation of Somatostatin Receptors (SSTR) 1–5 and Therapeutic Implications in Neuroendocrine and Non‐Neuroendocrine Malignancies

International Journal of Cancer, EarlyView.
ABSTRACT Somatostatin receptors (SSTR) mediate the antiproliferative, antisecretory, and proapoptotic effects of somatostatin and its synthetic analogs. Their surface expression on neuroendocrine tumor (NET) cells is required for somatostatin analog therapy and radiopharmaceutical therapy (RPT).
Neeraj Kumari, Pablo Hoffmann, Laura Reichl, Maximilian Schmutz, Nina Fischer, Thi Tuong Vi Dang, Fulvia Ferrazzi, Pascal Johann, Michaela Kuhlen, Constantin Lapa, Rainer Claus   +10 more
wiley   +1 more source

Regulation of chromatin architecture by protein binding: insights from molecular modeling. [PDF]

Biophys Rev
Portillo-Ledesma S, Schlick T.
europepmc   +1 more source

Nuclear actin-dependent Meg3 expression suppresses metabolic genes by affecting the chromatin architecture at sites of elevated H3K27 acetylation levels. [PDF]

Nucleic Acids Res
Hosny El Said N, Abdrabou W, Mahmood SR, Venit T, Idaghdour Y, Percipalle P.   +5 more
europepmc   +1 more source

Defining a chromatin architecture that supports transcription at RNA polymerase II promoters. [PDF]

J Biol Chem
Fisher MJ, Luse DS.
europepmc   +1 more source

Dynamic alternations of three-dimensional chromatin architecture contribute to phenotypic characteristics of breast muscle in chicken. [PDF]

Commun Biol
Wang Z, Tian W, Guo Y, Wang D, Zhang Y, Zhi Y, Li D, Li W, Li Z, Jiang R, Han R, Sun G, Li G, Tian Y, Li H, Kang X, Liu X.   +16 more
europepmc   +1 more source

Telomere-to-telomere genome assembly and 3D chromatin architecture of <i>Centella asiatica</i> insight into evolution and genetic basis of triterpenoid saponin biosynthesis. [PDF]

Hortic Res
Song WL, Chen BZ, Feng L, Chen G, He SM, Hao B, Zhang GH, Dong Y, Yang SC.   +8 more
europepmc   +1 more source

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Hexavalent chromium disrupts chromatin architecture

Seminars in Cancer Biology, 2021
Accessibility of DNA elements and the orchestration of spatiotemporal chromatin-chromatin interactions are critical mechanisms in the regulation of gene transcription. Thus, in an ever-changing milieu, cells mount an adaptive response to environmental stimuli by modulating gene expression that is orchestrated by coordinated changes in chromatin ...
Alvaro Puga, Hesbon Amenya Zablon, Andrew Vonhandorf   +2 more
exaly   +3 more sources

Chromatin architectural proteins

Chromosome Research, 2006
The accessibility of eukaryotic DNA is dependent upon the hierarchical level of chromatin organization. These include (1) intra-nucleosome interactions, (2) inter-nucleosome interactions and (3) the influence of non-histone chromatin architectural proteins.
Steven J, McBryant, Valerie H, Adams, Jeffrey C, Hansen   +2 more
openaire   +2 more sources