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STATISTICAL CURVE MODELS FOR INFERRING 3D CHROMATIN ARCHITECTURE. [PDF]
Tuzhilina E, Hastie T, Segal M.
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HMGA2 interacts with KAT6A to regulate MMPs chromatin architecture and promote triple-negative breast cancer metastasis. [PDF]
Qiao L +6 more
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Herpes simplex virus type 1 reshapes host chromatin architecture via transcription machinery hijacking. [PDF]
González-Almela E +7 more
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Hexavalent Chromium Disrupts Chromatin Architecture
Seminars in Cancer Biology, 2021Accessibility of DNA elements and the orchestration of spatiotemporal chromatin-chromatin interactions are critical mechanisms in the regulation of gene transcription. Thus, in an ever-changing milieu, cells mount an adaptive response to environmental stimuli by modulating gene expression that is orchestrated by coordinated changes in chromatin ...
Alvaro Puga +2 more
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Chromatin architectural proteins
Chromosome Research, 2006The accessibility of eukaryotic DNA is dependent upon the hierarchical level of chromatin organization. These include (1) intra-nucleosome interactions, (2) inter-nucleosome interactions and (3) the influence of non-histone chromatin architectural proteins.
Steven J, McBryant +2 more
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Tracing chromatin architecture
Nature Reviews Genetics, 2020A study in Cell presents a new approach that increases resolution and throughput compared with existing imaging methods and provides insights into the relationship between transcription and the 3D genome.
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PIQ-ing into chromatin architecture
Nature Biotechnology, 2014Decrypting the logic of gene regulation is aided by a breakthrough method for analyzing chromatin-accessibility data.
Sebastian, Rieck, Christopher, Wright
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Current Opinion in Structural Biology, 2006
A complete understanding of the structure-function relationships of chromatin requires extending primarily one dimensional information, obtained from molecular genetic techniques and based on the underlying linear DNA sequence, to the three dimensional conformation.
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A complete understanding of the structure-function relationships of chromatin requires extending primarily one dimensional information, obtained from molecular genetic techniques and based on the underlying linear DNA sequence, to the three dimensional conformation.
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Chromatin and nuclear architecture in the nervous system
Trends in Neurosciences, 2008Neurons are arguably the most varied cell type both morphologically and functionally. Their fate during differentiation and development and the activity of mature neurons are significantly determined and regulated by chromatin. The nucleus is compartmentalized and the arrangement of these compartments, termed the nuclear architecture, distinguishes one
Takumi, Takizawa, Eran, Meshorer
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