Results 191 to 200 of about 104,409 (252)

Protocol for chromatin immunoprecipitation using isolated antheridia of Marchantia polymorpha. [PDF]

STAR Protoc
Inoue K, Kotani K, Yamaoka S, Araki T.
europepmc   +1 more source

O‐GlcNAcylation of KAT2A Enhances Bladder Cancer Proliferation by Inhibiting the KAT2A‐TRIM22 Interaction

Cancer Science, EarlyView.
Lysine acetyltransferase 2A (KAT2A) is a transcriptional coactivator and a member of the Histone Acetyltransferase (HAT) family. While altered KAT2A activity has been implicated in various cancers, its role in bladder cancer (BLCA) remains poorly understood.
Wenjie Yang, Zhaoheng Jin, Ziyi Li, Weifeng Xu, Yingjie Li, Yueqiang Peng, Jie Dong, Lin Ma, Zhigang Ji   +8 more
wiley   +1 more source

Integrated analysis of ATAC-seq and RNA-seq reveals the TCP-ARF molecular module related to pathogenic process of phytoplasma infection in Paulownia fortunei. [PDF]

BMC Genomics
Huang S, Li B, Cao Y, Fan G.
europepmc   +1 more source

Chromatin Immunoprecipitation (ChIP) using Drosophila tissue. [PDF]

J Vis Exp, 2012
Tran V, Gan Q, Chen X.
europepmc   +1 more source

Blocking SETD2 Enhances the Therapeutic Efficiency of Menin Inhibitor in MLL‐Fusion Leukemia

Cancer Science, EarlyView.
Combined SETD2 and menin inhibitors make synergistic effects against MLL‐fusion leukemia; the combination therapy reduces the expression of target genes through blocking transcription elongation and initiation. ABSTRACT During transcriptional elongation, the histone methyltransferase SETD2 binds to RNA polymerase II and deposits trimethylation marks at
Anpei Li, Yuan Zhang, Ziwei Li, Anhao Liu, Li Zhang, Shubin Gao, Xiao Lin, Xiaoming Liu, Huan Li, Guanghui Jin, Bin Xu   +10 more
wiley   +1 more source

<i>CDCA7</i> Promotes Proliferation and Suppresses Apoptosis in Gastric Cancer via HELLS-Mediated Chromatin Remodeling. [PDF]

Oncol Res
Jiang J, Li YR, Wang X, Li J, Ye F, Wang J, Li H, Feng L.   +7 more
europepmc   +1 more source

Oncogenic BRAF and KRAS Promote Global DNA Hypomethylation Through a Directed Pathway That Upregulates TET3

Cancer Science, EarlyView.
Oncogenic BRAF and KRAS promote global DNA hypomethylation through a directed pathway that increases the levels of TET3, which helps drive tumorigenesis. ABSTRACT Aberrant epigenetic modification is one of the characteristics of the cancer genome.
Ichiro Onoyama, W. Rod Hardy, Shoichiro Takeishi, Lihua Julie Zhu, Yanglan Tan, Lloyd Hutchinson, Jianhong Ou, Leyuan Ma, Ching‐Man Virbasius, Masafumi Yasunaga, Keiichi I. Nakayama, Scott A. Shaffer, Michael R. Green   +12 more
wiley   +1 more source

SIRT2 antagonizes MOF function during mitotic entry. [PDF]

Sci Adv
Espinosa-Alcantud M, Sima N, Fernández-Duran I, Marazuela-Duque A, Martínez-Cebrián G, Guitart-Solanes A, Gámez-García A, Martínez-Redondo P, Bosch-Presegué L, Vazquez BN, Paños L, Bech JJ, Thomas T, Martinez-Balbás MA, Voss AK, Krüger M, Serrano L, Olivella M, Cuartero S, de la Torre C, Vaquero A.   +20 more
europepmc   +1 more source

Ezh2 Inhibits the Differentiation of Short‐Lived Effector CD8+ T Cells and Promotes T Cell‐Dependent Antitumor Immunity

Cancer Science, EarlyView.
The antitumor immune response is attenuated in T cell‐specific Ezh2 knockout mice. ABSTRACT Appropriate regulation of the differentiation balance between effector CD8+ T cells and memory CD8+ T cells is crucial for an appropriate immune response. We previously reported that the tumor suppressor menin suppresses the differentiation of CD8+ T cells into ...
Kenji Takagi, Junpei Suzuki, Yuko Matsuoka, Makoto Kuwahara, Taro Oshikiri, Masakatsu Yamashita   +5 more
wiley   +1 more source

Hypoxia-responsive interaction between P-TEFb, BHLHE40, and Tim8-Tim13 regulates hypoxic gene transcription. [PDF]

Sci Adv
Soliman SHA, De Fabritiis S, Iwanaszko M, Lin LA, Das M, Gold S, Andersen GD, Chakrabarty RP, Chandel NS, Shilatifard A.   +9 more
europepmc   +1 more source