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Chromatin-remodeling for transcription
Quarterly Reviews of Biophysics, 2017AbstractThe nucleosome serves as a general gene repressor, preventing all initiation of transcription except that which is brought about by specific positive regulatory mechanisms. The positive mechanisms begin with chromatin-remodeling by complexes that slide, disrupt, or otherwise alter the structure and organization of nucleosomes.
Yahli, Lorch, Roger D, Kornberg
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Chromatin remodeling and transcription
Current Opinion in Genetics & Development, 1997Recent advances highlight two important chromatin remodeling systems involved in the transcriptional process. One system includes several members of the evolutionarily conserved SWI2/SNF2 family found in distinct multiprotein complexes with ATP-dependent nucleosome destabilizing activity; the other is the enzymatic system that governs histone ...
T, Tsukiyama, C, Wu
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A glimpse into chromatin remodeling
Nature Structural & Molecular Biology, 2017Chromatin remodelers are ATP-driven enzymes that can slide nucleosomes along DNA. Chen and colleagues present a tantalizing ∼4-A view of the SWI/SNF ATPase motor bound to the nucleosome, which offers novel structural clues into the remodeling process.
Dale B, Wigley, Gregory D, Bowman
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Chromatin remodeling in plants
Current Opinion in Plant Biology, 2001In the past two years, a variety of forward genetic screens have revealed predicted plant chromatin remodeling components that are involved in either differential histone acetylation or ATP-dependent SWI2/SNF2-related complexes. Combined with the results of recent reverse genetic studies, these findings have begun to provide the groundwork for ...
M L, Verbsky, E J, Richards
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Control of Chromatin Remodeling
Critical Reviews in Eukaryotic Gene Expression, 2000Chromatin structure has a pivotal role in the regulation of gene expression. Transcriptional activation or the repression of a gene require the recruitment of multiple chromatin remodeling complexes. Chromatin remodeling complexes modulate the higher order structure of chromatin, facilitate or hinder the binding of transcription factors, and aid in or ...
J R, Davie, M, Moniwa
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2017
Many of the known SUMO substrates are nuclear proteins, which regulate gene expression and chromatin dynamics. Sumoylation, in general, appears to correlate with decreased transcriptional activity, and in many cases modulation of the chromatin template is implicated.
David, Wotton +2 more
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Many of the known SUMO substrates are nuclear proteins, which regulate gene expression and chromatin dynamics. Sumoylation, in general, appears to correlate with decreased transcriptional activity, and in many cases modulation of the chromatin template is implicated.
David, Wotton +2 more
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Current Opinion in Plant Biology, 2001
Epigenetic mechanisms are heritable traits that are mediated by changes in a genetic locus that do not involve a modification at the nucleotide level. As eukaryotic DNA is organised in chromatin units, epigenetic modifications can be mediated by chromatin remodelling.
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Epigenetic mechanisms are heritable traits that are mediated by changes in a genetic locus that do not involve a modification at the nucleotide level. As eukaryotic DNA is organised in chromatin units, epigenetic modifications can be mediated by chromatin remodelling.
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Chromatin Remodeling and Transcription
Journal of Biochemistry, 1998The chromatin structure is essential not only for the compact packaging of the eukaryotic genome but also for regulation of transcription. This article provides an overview of chromatin modification upon transcriptional activation or repression, and chromatin remodeling.
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The Biochemistry of Chromatin Remodeling
Biochemistry, 2016In this perspective, the author describes the current state of biochemical studies of chromatin remodeling, summarizes Current Topics articles contained within this special issue of the journal and provides his views on future needs in the field of chromatin remodeling biochemistry.
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Science's STKE, 2005
This Teaching Resource provides lecture notes and slides for a class covering chromatin remodeling mechanisms and is part of the course "Cell Signaling Systems: a Course for Graduate Students." The lecture begins with a discussion of chromatin organization and then proceeds to describe the process of chromatin remodeling through a review of chromatin ...
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This Teaching Resource provides lecture notes and slides for a class covering chromatin remodeling mechanisms and is part of the course "Cell Signaling Systems: a Course for Graduate Students." The lecture begins with a discussion of chromatin organization and then proceeds to describe the process of chromatin remodeling through a review of chromatin ...
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