Results 111 to 120 of about 201,890 (354)
SnapShot: Chromatin Remodeling Complexes
Cell, 2007 Ino80 dIno80 hIno80 Swr1 SRCAP Domino P400Rvb1, Rvb2 Reptin, Pontin Tip49a, Tip49b Rvb1, Rvb2 Tip49a, Tip49b Reptin, Pontin Tip49a, Tip49bArp4,5,8, Act1 dArp5,8, dActin BAF53a, Arp5,8 Arp4,6, Act1 BAF53a, Arp6 BAP55, Act87E BAF53a, Actin Arp4, Act1Taf14 Yaf9 GAS41 dGAS41 GAS41 Yaf9Ies2 hIes2Ies6 hIes6Swc4/Eaf2 DMAP1 dDMAP1 DMAP1 Swc4/Eaf2Swc2/Vps72 YL ...
Bao, Yunhe, Shen, Xuetong
openaire +2 more sources
Progressive Insights into 3D Bioprinting for Corneal Tissue Restoration
Advanced Healthcare Materials, EarlyView.This review explores the potential of 3D bioprinting to replicate the complex structure and function of the human cornea. It highlights key advances in bioink development, printing modalities, and in vivo performance, while addressing current challenges and emerging strategies. The review emphasizes bioprinting's promise to overcome donor shortages and
Ilayda Namli +6 more
wiley +1 more source
Activation of gene expression by histone deubiquitinase OTLD1
Epigenetics, 2017 One of the main mechanisms of epigenetic control is post translational modification of histones, and one of the relatively less characterized, yet functionally important histone modifications is monoubiquitylation, which is reversed by histone ...
Ido Keren, Vitaly Citovsky
doaj +1 more source
The Space Within: How Architected Voids Promote Tissue Formation
Advanced Materials, EarlyView.This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou +3 more
wiley +1 more source
Macrophages Mediate Mesoscale Brain Mechanical Homeostasis
Advanced Materials, EarlyView.We investigated the role of infiltrating immune cells in sculpting the developing brain. Using Brillouin microscopy and active microrheology, we found microglia actively maintain tissue viscoelasticity. Moreover, colony stimulating factor one receptor (CSF1R)‐driven stromal remodeling alters brain mechanics in vivo. These findings link immune activity,
Woong Young So +11 more
wiley +1 more source
DNA repair synthesis and histone deposition partner during homologous recombination
Molecular & Cellular Oncology, 2018 Chromatin remodeling is critical for the regulation of the DNA damage response. We highlight findings from our recent study showing that the deposition of the histone variant H3.3 by the alpha-thalassemia mental retardation X-linked protein (ATRX) and ...
Amira Elbakry +3 more
doaj +1 more source
Epigenetics and chromatin remodeling play a role in lung disease [PDF]
, 2011 Epigenetics is defined as heritable changes that affect gene expression without altering the DNA sequence. Epigenetic regulation of gene expression is facilitated through different mechanisms such as DNA methylation, histone modifications and RNA ...
Adcock, IM +3 more
core +1 more source
Identification of H3K4me1-associated proteins at mammalian enhancers. [PDF]
, 2017 Enhancers act to regulate cell-type-specific gene expression by facilitating the transcription of target genes. In mammalian cells, active or primed enhancers are commonly marked by monomethylation of histone H3 at lysine 4 (H3K4me1) in a cell-type ...
Albuquerque, Claudio P +13 more
core +2 more sources
Mechanobiological Dynamics‐Inspired Mechanomodulatory Biomaterials
Advanced Science, EarlyView.Recent advances in biomaterial‐mediated mechanomodulation of stem cell fate, encompassing 2, 3, and 4D systems and their synergy with artificial intelligence is overviewed. By integrating knowledge from diverse fields, this review ultimately aims to inspire the design of smarter biomaterial systems that can accelerate the clinical translation of ...
Letao Yang +6 more
wiley +1 more source