Results 171 to 180 of about 539,283 (308)

Chromatin remodeling-driven autophagy activation induces cisplatin resistance in oral squamous cell carcinoma

open access: yesCell Death and Disease
It is still challenging to predict the efficacy of cisplatin-based therapy, particularly in relation to the activation of macroautophagy/autophagy in oral squamous cell carcinoma (OSCC). We studied the effect of selected chromatin remodeling genes on the
Su Young Oh   +9 more
doaj   +1 more source

Modular Organization and Assembly of SWI/SNF Family Chromatin Remodeling Complexes

open access: yesCell, 2018
N. Mashtalir   +14 more
semanticscholar   +1 more source

Mitochondria‐Localized Nestin Protects Mesenchymal Stem Cells from Senescence by Maintaining Cristae Structure and Function

open access: yesAdvanced Science, EarlyView.
Nestin localizes to the mitochondrial IMS through its MTS and the TOM20 import machinery. Within the mitochondria, Nestin interacts with Mic60 via its C‐terminal Tail3 domain. Loss of mitochondrial Nestin disrupts cristae architecture, leading to mitochondrial swelling, bioenergetic dysfunction, and ultimately the senescence of hMSCs.
Hainan Chen   +14 more
wiley   +1 more source

H1.3 depletion in AML cells prompts H1.2 redistribution, chromatin remodeling and cell cycle defects [PDF]

open access: green
Clara Tellez-Quijorna   +6 more
openalex   +1 more source

Histone H3 Lysine 36 Methylation Targets the Isw1b Remodeling Complex to Chromatin [PDF]

open access: bronze, 2012
Vicki E. Maltby   +7 more
openalex   +1 more source

Ovulatory signal-triggered chromatin remodeling in ovarian granulosa cells by HDAC2 phosphorylation activation-mediated histone deacetylation [PDF]

open access: gold, 2023
Jiamin Jin   +9 more
openalex   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

ChromNet: A Multi‐Task Learning Framework for Cross‐Cell Type Prediction of 3D Chromatin Interactions Using Epigenetic Signals

open access: yesAdvanced Science, EarlyView.
ChromNet enables accurate cross‐cell‐type prediction of chromatin architecture from DNA and epigenetic profiles alone, capturing both conserved and cell‐type‐specific (including disease‐associated) structural features. Its noise‐perturbed multi‐task learning design enhances generalization, enabling precise reconstruction of 3D genome organization even ...
Bin Wang   +5 more
wiley   +1 more source

Retinoic Acid Receptor α Fusion to PML Affects Its Transcriptional and Chromatin-Remodeling Properties

open access: green, 2003
Simona Segalla   +6 more
openalex   +2 more sources

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