Highly discriminative globin gene activation by the noncanonical BAF chromatin remodeling complex. [PDF]
Bagchi A +15 more
europepmc +1 more source
Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao +8 more
wiley +1 more source
Chromatin-Remodeling Factor CHR5 Promotes Defense Gene Expression and SA Accumulation. [PDF]
Liu X +5 more
europepmc +1 more source
CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language [PDF]
Fiala, Elise, Willing, Marcia
core +1 more source
T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu +7 more
wiley +1 more source
Chromatin remodeling by HIRA and FAS2 restricts geminivirus pathogenesis in plants. [PDF]
Sultana S, Gupta N, Chakraborty S.
europepmc +1 more source
SnapShot: Chromatin Remodeling: ISWI
Yadon, Adam N., Tsukiyama, Toshio
openaire +2 more sources
Integrating Spatial Proteogenomics in Cancer Research
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang +13 more
wiley +1 more source
The NuRD chromatin remodeling complex contributes to repairing exogenous double-strand breaks in the Caenorhabditis elegans germline. [PDF]
Ananthaswamy D +7 more
europepmc +1 more source
Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu +8 more
wiley +1 more source

