Results 191 to 200 of about 201,890 (354)

The PBAP chromatin remodeling complex mediates summer diapause via H3K4me3-driven juvenile hormone regulation in Colaphellus bowringi [PDF]

Zhong Tian, Kou Wang, Shuang Guo, Jia‐Xu Li, Kirst King‐Jones, Fen Zhu, Wen Liu, Xiaoping Wang   +7 more
openalex   +1 more source

The chromatin remodeler SMARCD3 regulates cell cycle progression and its expression predicts survival outcome in ER+ breast cancer [PDF]

, 2019
Romain Tropée, Bárbara de la Peña Avalos, Madeline Gough, Cameron Snell, Pascal H. G. Duijf, Eloïse Dray   +5 more
openalex   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, EarlyView.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Temporal Transcriptional Regulation of Human Neuronal Differentiation via Forward Programming

Advanced Science, EarlyView.
Single‐cell profiling of TF‐induced forward programming versus stepwise dual‐SMAD differentiation reveals that divergent trajectories set the pace of neurogenesis. OLIG TFs advance cell‐cycle exit via NOTCH modulation, while NEUROD2 later accelerates maturation. The study elucidates transcriptional mechanisms governing differentiation timing, providing
Lingling Zhu, Weiguang Wang, Jian Zhang, Lei Liu, Minpeng Huang, Lei Diao, Shuang Feng, Qiong Yang, Hao Qiu, Bing Pan, Renee A Reijo Pera, Ji Liu, Ninuo Xia, Fang Fang   +13 more
wiley   +1 more source

Bacterial chromatin remodeling associated with transcription-induced domains at pathogenicity Islands. [PDF]

Nat Commun
Kortebi M, Bourge M, Le Bars R, Van Dijk E, Dorman CJ, Bury-Moné S, Boccard F, Lioy VS.   +7 more
europepmc   +1 more source

Nanoscale Visualization of the Chromatin Remodeling as Potent Biomarker in Aggressive Breast Cancers

Chayan Kanti Nandi, Farhan Anjum, Kush Kaushik, Abdul Salam   +3 more
openalex   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source

In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling [PDF]

, 2019
Zainab Jagani, Gregg Chenail, Kay X. Xiang, Geoffrey Bushold, Hyo‐eun C. Bhang, Ailing Li, GiNell Elliott, Jiang Zhu, Anthony Vattay, Tamara J. Gilbert, Anka Bric, Rie Kikkawa, Valérie Dubost, Rémi Terranova, John Cantwell, Catherine A. Luu, Serena J. Silver, Matt Shirley, François Huet, Rob Maher, John Reece-Hoyes, David A. Ruddy, Daniel P. Rakiec, Joshua M. Korn, Carsten Russ, Vera M. Ruda, Julia Dooley, Emily A. Costa, Isabel Park, Henrik Moebitz, Katsumasa Nakajima, Christopher D. Adair, Simon Mathieu, Rukundo Ntaganda, Troy Smith, David Farley, Daniel King, Xiaoling Xie, Raviraj Kulathila, Tiancen Hu, Xuewen Pan, Qicheng Ma, Katarina Vulic, Florencia Rago, Scott Clarkson, Robin Ge, Frederic Sigoillot, Gwynn Pardee, Linda Bagdasarian, Margaret E. McLaughlin, Kristy Haas, Jan Weiler, Steve G. Kovats, Mariela Jaskelioff, Marie Apolline-Gerard, Johanna Beil, Ulrike Naumann, Pascal D. Fortin, Frank Stegmeier, Michael Acker, Juliet Williams, Matthew J. Meyer, James E. Bradner, Nicholas Keen, William R. Sellers, Francesco Hofmann, Jeffrey A. Engelman, Darrin D. Stuart, Julien P. N. Papillon   +68 more
openalex   +1 more source

RUNX2 Activation in Fibro/Adipogenic Progenitors Promotes Muscle Fibrosis in Muscular Dystrophy

Advanced Science, EarlyView.
This study revealed a novel role of the chemokine‐TGF‐β1‐RUNX2 axis in determining the fate of FAP differentiation and modulating muscle fibrosis in patients and mice with muscular dystrophies. ABSTRACT Clinical evidence indicates concurrent muscle inflammation and fibrosis in muscular dystrophies (MDs); however, the molecular mechanisms underlying ...
Pengkai Wu, Zehua Zhang, Kai Zheng, Ziqi Zhu, Yong Zhu, Abdukahar Kiram, Lei Zhao, Huihui Chen, Zhu Xu, Xihua Li, Beicheng Sun, Zhijian Li, Dengqiu Xu   +12 more
wiley   +1 more source

Prognostic chromatin remodeling signature stratifies survival outcomes in lung adenocarcinoma patients. [PDF]

Transl Cancer Res
Wang X, Liu Y, Huang D, Yuan M, Hong L.
europepmc   +1 more source