Results 201 to 210 of about 201,890 (354)

Chromatin remodeler Chd7 regulates reactive astrogliosis after ischemic stroke

Motoshi Nagao, Takahiro Maekawa, Ayako Yamazaki, Toru Ogata   +3 more
openalex   +1 more source

GENE-16. CLINICALLY AGGRESSIVE MENINGIOMAS ARE CHARACTERIZED BY MUTATIONAL SIGNATURES ASSOCIATED WITH DEFECTIVE DNA REPAIR AND MUTATIONS IN CHROMATIN REMODELING GENES [PDF]

, 2018
Sylvia C. Kurz, Benjamin Liechty, Stephen Kelly, Varshini Vasudevaraja, Ramona Bledea, Peter Wu, Jonathan Serrano, Leah Katz, Joshua S. Silverman, Donato Pacione, John G. Golfinos, Andrew Chi, Matija Snuderl   +12 more
openalex   +1 more source

Data from SNF5/INI1 Deficiency Redefines Chromatin Remodeling Complex Composition during Tumor Development

, 2023
Darmood Wei, Dennis Goldfarb, Shujie Song, Courtney Cannon, Feng Yan, Donastas Sakellariou-Thompson, Michael J. Emanuele, Michael B. Major, Bernard E. Weissman, Yasumichi Kuwahara   +9 more
openalex   +1 more source

Allelic Variation in Maize Malate Dehydrogenase 7 Shapes Promoter Methylation and Banded Leaf and Sheath Blight Resistance

Advanced Science, EarlyView.
In this study maize chloroplastic malate dehydrogenase7 (ZmMDH7), is identified as a Rhizoctonia solani resistance gene in maize. ZmMDH7 is regulated by transcription factor ZmWRKY44 via pathogens challenge to elevate mitochondrial ROS and SA signaling pathway.
Luyang Wei, Junbin Chen, Chuang Liu, DanDan Liu, Meida Du, Shengfeng He, Wenyu Cheng, Vijai Bhadauria, You‐Liang Peng, Wangsheng Zhu   +9 more
wiley   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

Targeting chromatin remodeling complexes to treat uveal melanoma. [PDF]

Elife
Nilsson JA.
europepmc   +1 more source

Proteogenomic Characterization Reveals Metabolic Vulnerabilities and Aberrant Phosphorylation in Colorectal Metastasis to Liver

Advanced Science, EarlyView.
This study provides a multi‐omics landscape of treatment‐naïve colorectal liver metastasis and reveals dysregulated molecules and cellular pathways. SHMT1 and NDRG1 Ser330 phosphorylation are demonstrated to display crucial roles in tumorigenesis and liver metastasis. Two proteomics subtypes (metabolism and RNA function) with distinct clinical outcomes
Wensi Zhao, Lei Zhao, Yannan Lian, Zhiwei Liu, Yaqi Li, Xuege Wang, Mingya Zhang, Ni Li, Jingli Guo, Danqing Shen, Shaobo Mo, Jiahao Li, Linhui Zhai, Jiahui Ni, Sangkyu Lee, Bin Liu, Jing Li, Fei Wang, Junjie Peng, Jun Qin, Minjia Tan   +20 more
wiley   +1 more source

SLC25A3 promotes hepatocellular carcinoma progression by inducing mitochondrial dysfunction and chromatin remodeling. [PDF]

Transl Cancer Res
Deng S, Fu J.
europepmc   +1 more source

Referee report. For: Expression status transition of NOTCH1 accompanies chromatin remodeling in human early retinal progenitor cells [version 2; peer review: 2 approved with reservations]

Zhongjie Tang
openalex   +1 more source

Smoking‐Induced STC2+ Tumor Cells Drive Tumor‐Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single‐Cell Transcriptomics

Advanced Science, EarlyView.
This study identifies a smoking‐induced mechanism in LSCC whereby nicotine activates the CHRNA5–JAK2/STAT3 axis to drive STC2 transcription. STC2 upregulates TGFBI, which interacts with endothelial ITGA5 to regulate vascular permeability and promote metastasis.
Yujie Shen, Lianchong Gao, Qiang Huang, Liang Zhou, Chengzhi Xu, Chunping Wu   +5 more
wiley   +1 more source