Results 201 to 210 of about 1,195,650 (280)

Identification of <i>Fasciola hepatica</i> gut-associated glycoproteins as potential vaccine candidates by lectin-affinity chromatography, flukicidal monoclonal antibodies, and affinity-enrichment mass spectrometry. [PDF]

Front Parasitol
Rechsteiner SG, Hasler S, Gehrig P, Deplazes P, Eichenberger RM.   +4 more
europepmc   +1 more source

Setting expectations for current and future directions of native mass spectrometry in the biopharmaceutical industry. [PDF]

MAbs
Hecht E, Martin E, Liko I, Mahan A, Sahasrabuddhe A, Tajoddin NN, Campuzano IDG.   +6 more
europepmc   +1 more source

Interference of ATP‐Binding Cassette Transporter by Functional Nano‐Delivery System for High Efficiency Management of Insecticide‐Resistant Nilaparvata lugens

Advanced Science, EarlyView.
A ZIF‐90 nanocarrier delivers dinotefuran and suppresses NlABCG3 and NlABCH1 in resistant Nilaparvata lugens. This system combines pH/ATP‐triggered release with enhanced foliar retention, improving efficacy while sparing honeybees and promoting rice growth, offering a promising resistance‐breaking strategy.
Chengshuai He, Hejun Ren, Shuo Zhang, Jikang Cheng, Hui Zhang, Jiao Liu, Sijie Wang, Congfen Gao, Yanchao Zhang, Yunhao Gao   +9 more
wiley   +1 more source

rAAV production cost analysis: Indication-specific cost per dose and reduction strategies. [PDF]

Gene Ther
Park MT, Matuszek D, Andaluz A, Motevalian SP.   +3 more
europepmc   +1 more source

UFL1‐Mediated UFMylation of ENO1 Restrains Aerobic Glycolysis and Colorectal Cancer Progression

Advanced Science, EarlyView.
UFMylation restrains aerobic glycolysis and colorectal cancer progression by modifying the glycolytic enzyme ENO1. Pharmacological enhancement of the UFL1–ENO1 interaction by the FDA‐approved antibiotic torezolid promotes ENO1 UFMylation, suppresses tumor metabolism, and sensitizes colorectal cancer to chemotherapy, revealing an actionable metabolic ...
Xiuqing Ma, Rui Wan, Yueyuan Zhong, Ziyang Cui, Xuan Zhang, Xiaoqiang He, Rong Wang, Lei Huang, Wan‐Yang Sun, Rong‐Rong He, Yang Zhou, Jianshuang Li, Li Shen, Shao‐Hua Wang, Tongzheng Liu   +14 more
wiley   +1 more source

Mapping the Brain Interaction Network of the Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Targeted by Leucettinib-21 Using Affinity Chromatography. [PDF]

ACS Pharmacol Transl Sci
Deau E, Simon C, Hogrel G, Caillette J, Dairou J, Herault Y, Morlet B, Miyata Y, Meijer L, Lindberg MF.   +9 more
europepmc   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

Low-affinity IgG-mediated macro-TSH: diagnostic limitations of peak-based gel filtration chromatography-a case report with review of literature. [PDF]

Endocr J
Kasahara T.
europepmc   +1 more source

Selection of Functional Glycoforms in Anti-SARS-CoV-2 Human IgG1 Monoclonal Antibodies by FcγRIIIa Affinity Chromatography and Mass Spectrometry. [PDF]

J Med Chem
Oliviero B, Kumar S, Conteianni D, Donetti G, Cerino A, Iraci AS, La Gaipa A, Ottolini S, Tengattini S, Massolini G, Cassaniti I, Sammartino JC, Mele D, Baldanti F, Forneris F, Faravelli S, Scotti C, Pessino G, Maggi M, Mantovani S, Temporini C, Mondelli MU, Terreni M.   +22 more
europepmc   +1 more source