Results 41 to 50 of about 519,147 (169)

Singular Shocks in a Chromatography Model [PDF]

open access: yesJournal of Mathematical Analysis and Applications, volume 439, issue 2, year 2016, pages 766-797, 2015
We consider a system of two equations that can be used to describe nonlinear chromatography and produce a coherent explanation and description of the unbounded solutions (singular shocks) that appear in M. Mazzotti's model. We use the methods of Geometric Singular Perturbation Theory, to show existence of a viscous solution to Dafermos-DiPerna ...
arxiv   +1 more source

Ligand Screening of Membrane Proteins Embedded in Nanodiscs: How to Manage Non-Specific Interactions in Weak Affinity Chromatography?

open access: yesMolecules
Miniaturized weak affinity chromatography is emerging as an interesting alternative to conventional biophysical tools for performing fragment-screening studies in the context of fragment-based drug discovery.
François-Xavier Vidal   +6 more
doaj   +1 more source

Effect of hemoglobin, triglyceride, and urea in different concentrations on compatibility between methods used in HbA1c measurement

open access: yesTürk Biyokimya Dergisi, 2022
The variability between methods is seen in the existence of hemoglobin (Hb), triglyceride (TG), blood urea nitrogen (BUN) and glucose in the specimens, which can affect the measurement.
Muhtaroglu Sabahattin   +2 more
doaj   +1 more source

Analysis of free analyte fractions by rapid affinity chromatography [PDF]

open access: yes, 2004
The invention is generally directed toward an analytical method to determine the concentration of the free analyte fraction in a sample. More particularly, the method encompasses applying a sample comprising a free and bound analyte fraction to an ...
Clarke, William A., Hage, David S.
core   +1 more source

A high-affinity antibody against the CSP N-terminal domain lacks Plasmodium falciparum inhibitory activity [PDF]

open access: yes, 2020
Malaria is a global health concern and research efforts are ongoing to develop a superior vaccine to RTS,S/AS01. To guide immunogen design, we seek a comprehensive understanding of the protective humoral response against Plasmodium falciparum ...
Bosch, A.   +15 more
core   +2 more sources

WENO scheme on characteristics for the equilibrium dispersive model of chromatography with generalized Langmuir isotherms [PDF]

open access: yesApplied Numerical Mathematics 201 (2024) 247-264
Column chromatography is a laboratory and industrial technique used to separate different substances mixed in a solution. Mathematically, it can be modelled using non-linear partial differential equations whose main ingredients are the adsorption isotherms, which are non-linear functions modelling the affinity between the different substances in the ...
arxiv   +1 more source

Endogenous mammalian lectin localized extracellularly in lung elastic fibers. [PDF]

open access: yes, 1984
An affinity-purified antibody preparation raised against a beta-galactoside-binding lectin from bovine lung was used to localize a similar lectin in rat lung by immunofluorescence and by electron microscopy after on-grid staining visualized with ...
Barondes, SH   +2 more
core   +3 more sources

APPLICATION OF IMMUNOGLOBULIN-BINDING PROTEINS A, G, L IN THE AFFINITY CHROMATOGRAPHY [PDF]

open access: yesBiotechnologia Acta, 2014
Proteins A, G and L are native or recombinant proteins of microbial origin that bind to mammalian immunoglobulins. Preferably recombinant variants of proteins A, G, L are used in biotechnology for affinity sorbents production. Сomparative characteristics
О. V. Sviatenko, O. B. Gorbatiuk
doaj   +1 more source

Extending the Affinity Range of Weak Affinity Chromatography for the Identification of Weak Ligands Targeting Membrane Proteins

open access: yesMolecules, 2023
The identification of weak-affinity ligands targeting membrane proteins is of great interest in Fragment-Based Drug Design (FBDD). Recently, miniaturized weak affinity chromatography (WAC) has been proposed as a valuable tool to study interactions ...
Adrien Deloche   +5 more
doaj   +1 more source

Production and Purification of a Polyclonal Antibody Against Purified Mouse IgG2b in Rabbits Towards Designing Mouse Monoclonal Isotyping Kits [PDF]

open access: yesAdvanced Pharmaceutical Bulletin, 2015
Purpose: Mouse IgG subclasses containing IgG1, IgG2a, IgG2b and IgG3 have been defined and described both physiochemically and immunologically. Methods: Sepharose beads conjugated with protein A affinity chromatography was used for purification of mouse
Sadeq Eivazi   +8 more
doaj   +1 more source

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