Results 31 to 40 of about 16,890 (184)

Mussel Spermatozoa Express a Specific Isoform of the Catalytic Subunit of cAMP‐Dependent Protein Kinase

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT cAMP‐dependent protein kinase (PKA) plays a central role in regulating sperm motility in both invertebrates and mammals. The sea mussel Mytilus galloprovincialis provides a valuable model for investigating the molecular mechanisms underlying gamete activation in externally fertilizing organisms.
Izaskun Ibarguren, Saskia‐Camille Flament‐Simon, Ana P. Losada, Susana. B. Bravo, José Antonio Villamarín   +4 more
wiley   +1 more source

Tetrastigma Hemsleyanum Polysaccharide Suppresses Triple‐Negative Breast Cancer by Disrupting the Hippo‐YAP/TEAD4‐PDIA4 Axis and Endoplasmic Reticulum Stress Adaptation

Advanced Science, Volume 13, Issue 34, 19 June 2026.
ABSTRACT Triple‐negative breast cancer (TNBC) exhibits addiction to chronic endoplasmic reticulum (ER) stress, which sustains an aggressive metastatic phenotype through activation of the unfolded protein response (UPR). Here, we identify a previously unrecognized “ER‐stress addiction” axis in which the Hippo pathway effector TEAD4 directly ...
Yini Shang, Wentao Si, Youxue Zhang, Jialin Liu, Huaixi Zhang, Yafei Li, Hongmeng Su, Wei Jiang, Zhishan Ding, Lihong Wang   +9 more
wiley   +1 more source

Induction of Apoptosis in MCF‐7 Breast Cancer Cells by Selenium Nanoparticles Synthesized With Laccase Enzyme Isolated From Pleurotus Floridanus

eFood, Volume 7, Issue 3, June 2026.
This study showed the first successful synthesis of selenium nanoparticles (SeNPs) using laccase purified from Pleurotus floridanus, offering an eco‐friendly and biocompatible replacement to conventional chemical methods. The biosynthesized SeNPs exhibited significant antiproliferative effects on MCF‐7 breast cancer cells, with cell cycle analysis ...
Shenbhagaraman Ramalingam, Arthi Karunanithi, Ammar B. Altemimi, Jenefar Sudarson, Sakthivel Muthu, Kodiganti Naresh Kumar, Rawaa H. Tlay, Tarek Gamal Abedelmaksoud   +7 more
wiley   +1 more source

Proteinaceous Protease Inhibitor from : Purification, Characterization and Antibacterial Activity

Natural Product Communications, 2013
A thermo-stable, proteinaceous protease inhibitor (LPI) from Lawsonia inermis is reported. The LPI was purified from Lawsonia inermis seeds by subsequent ammonium sulfate precipitation, ion exchange chromatography (DEAE-Cellulose) and gel permeation ...
Arvind Dabhade, Priti Patel, Ulhas Patil
doaj   +1 more source

Structural Characterization of Ginseng Adventitious Root Polysaccharides and Their Effects on Ameliorating Insulin Resistance

eFood, Volume 7, Issue 3, June 2026.
Purified ginseng adventitious root polysaccharides (GARP) improve insulin resistance by enhancing glucose and lipid metabolism and reducing oxidative stress. These beneficial effects are mediated, at least in part, through activation of the Nrf2/Keap1 signaling pathway in cellular and animal models.
Tian‐fu Yang, Ting‐ting Hu, Xiao‐di Zhuang, Yi‐lun Zhou, Xin Qi, Cheng‐bi Cui   +5 more
wiley   +1 more source

Separation of Bovine Serum Albumin Using Chromatographical Column: Parameters and Simulation

Iraqi Journal of Chemical and Petroleum Engineering, 2010
A liquid-solid chromatography of Bovine Serum Albumin (BSA) on (diethylaminoethyl-cellulose) DEAE-cellulose adsorbent is worked experimentally, to study the effect of changing the influent concentration of (0.125, 0.25, 0.5, and 1 mg/ml) at constant ...
Cecilia Khoshaba Haweel, Ahmed J. Ali, Samar N. Alias   +2 more
doaj  

PREPARATION OF PEPTIDE HYDROLYSATES FROM BETA CASEIN ISOLATED AND PURIFIED FROM IRAQI CAMEL MILK

The Iraqi Journal of Agricultural science
The current study aimed to isolate and purify the Beta Casein (β-CN) protein from Iraqi Camel milk by urea, and ion exchange chromatography using a DEAE-Cellulose column, and gel filtration by using a Sephadex-G100 column, determining the molecular ...
Sharaf. Ali. Hadi. Al-Shaikh, Kifah. Saed. Doosh   +1 more
doaj   +1 more source

Structural Characterization and Anti-inflammatory Activity of a Galactorhamnan Polysaccharide From Citrus medica L. var. sarcodactylis

Frontiers in Nutrition, 2022
This study aimed to extract polysaccharides from Citrus medica L. var. sarcodactylis (finger citron fruits) and analyze their structures and potential bioactivities.
Bi Luo, Bi Luo, Bi Luo, Jia Lv, Jia Lv, Jia Lv, Kejie Li, Kejie Li, Kejie Li, Peiran Liao, Peiran Liao, Peiran Liao, Peng Chen   +12 more
doaj   +1 more source

Extraction, Structural Characterization and Anti‐Inflammatory Activity of Polysaccharides From Conioselinum vaginatum

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
This study employed an ultrasonic‐assisted extraction (UAE) method combined with column chromatography purification to obtain two homogeneous polysaccharides (CVP‐I and CVP‐II) from Conioselinum vaginatum, which exhibited distinct physicochemical properties and structural characteristics, and exerted anti‐inflammatory effects by inhibiting the ...
Conghui Ren, Yuhao Cui, Junlong Wang, Qingyou Fu, Shenghui Chen, Jie Li, Yonggang Lin   +6 more
wiley   +1 more source

Molecular Pharming: Advances, Applications, and Future Prospects in Biotechnology and Medicine

Engineering in Life Sciences, Volume 26, Issue 3, March 2026.
ABSTRACT Genetically engineered plants incorporate the use of a novel bioreactor known as molecular pharming, which has a transformative view on the pharmaceutical industry. The technique enables mass production, at a low cost, and reproducibly of a large number of different protein‐based drugs, vaccines, and industrial enzymes. This review‐based study
Md. Hridoy Ahmed, Md. Mustak Khan, Shishir Dutta, Md. Foyzur Rahman, Mohammad Shariful Islam, Md. Najmul Hosen, Md. Saad Hossain, Md. Aftabur Rahman, Md. Sadman Hasan Sahil, Tanjuma Tasnim Hira, Ifthesum, Ashikur Rahaman, Md. Afser Rabbi, Laila Khaleda   +13 more
wiley   +1 more source