Results 91 to 100 of about 125,999 (289)

The derivation of bioprocess understanding from mechanistic models of chromatography

, 2015
This thesis, completed in collaboration with Purification Process Development of Pfizer Biotherapeutics, is concerned with how mechanistic models of chromatographic bioseparations can be applied in industry to accelerate development and increase ...
Close, EJ
core  

Designing Strong, Tough, Fire‐Retardant and Self‐Healing Elastomers with Phosphorus/Nitrogen‐ and Biphenyl‐Containing Segments

Advanced Materials, EarlyView.
By designing a P/N‐ and π–π interacting biphenyl‐containing diol as hard segments but side groups, a strong, tough, fire‐extinguishing and self‐healing elastomer is developed, demonstrating a break strain of ∼2500%, a toughness of 379 MJ/m3 and a tensile strength of 46 MPa, as well as a healing efficiency of 95% (tensile strength) and 99% (break strain)
Yijiao Xue, Shu Gong, Zhezhe Zhou, Zhewen Ma, Yanlong Luo, Mark Lynch, Jiabing Feng, Yan Zhang, Meng Zhang, Yonghong Zhou, Wenlong Cheng, Pingan Song   +11 more
wiley   +1 more source

Improvement in protein separation by pH excursion modulated ion-exchange chromatography

Journal of Chromatography Open
The transient change in pH during the elution step in ion exchange chromatography is commonly referred to as pH excursion. Acidic pH excursion is usually observed during salt-based elution in cation exchange chromatography.
Raja Ghosh
doaj   +1 more source

Design of two-column batch-to-batch recirculation to enhance performance in ion-exchange chromatography

, 2018
Preparative liquid chromatography is a separation technique widely used in the manufacturing of fine chemicals and pharmaceuticals. A major drawback of traditional single-column batch chromatography step is the trade-off between product purity and ...
Nilsson, Bernt,, Lund University., Andersson, Niklas,, Persson, Oliver,   +3 more
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An Advanced Molecularly Imprinted Polymer‐Based Electrochemical Aptasensor for Carbendazim Detection

Advanced Materials Interfaces, EarlyView.
A dual‐recognition electrochemical aptasensor that integrates a molecular imprinted polymer (MIP) and an aptamer is developed for the detection of a common pesticide, carbendazim (CBZ). The resulting sensor exhibits enhanced selectivity toward CBZ over structurally similar compounds and achieves a low detection limit of 1.3 nm, demonstrating its ...
Suthira Pushparajah, Mahnaz Shafiei, Peter J. Mahon, Aimin Yu   +3 more
wiley   +1 more source

Characterization of Complex Proteoform Mixtures by Online Nanoflow Ion-Exchange Chromatography - Native Mass Spectrometry

The characterization of proteins and complexes in biological systems is essential to establish their critical properties and to understand their unique functions in a plethora of bioprocesses.
Francesco G., Mutti, Andrea F.G., Gargano, Despoina, Mavridou, Matteo, Damian, Peter J., Schoenmakers, Ziran, Zhai   +5 more
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Microscopic insight into role of protein flexibility during ion exchange chromatography by nuclear magnetic resonance and quartz crystal microbalance approaches

, 2016
Driven by the prevalent use of ion exchange chromatography (IEC) for polishing therapeutic proteins, many rules have been formulated to summarize the different dependencies between chromatographic data and various operational parameters of interest based
Zhao, Lan, Ma, GH, Ma, Guanghui, Su, Zhiguo, Hao, Dongxia, Huang, Yongdong, Ge, Jia   +6 more
core   +1 more source

Interface‐Engineered Binary Framework Composites: Advancing Porous Materials for Precision Medicine

Advanced Materials Interfaces, EarlyView.
Binary framework composites integrate two complementary porous architectures into a unified platform, enabling multifunctional design, enhanced structural tunability, and improved physicochemical performance. By combining high surface area, ordered porosity, interfacial synergy, and versatile functionalization, these hybrid materials offer new ...
Navid Rabiee, Mohammad Rabiee, Mohammad Akrami‐Hasan‐Kohal, Sidi A. Bencherif   +3 more
wiley   +1 more source

Corrosion behavior of aluminum in ion exchange resin leachates from cooling systems in high-voltage direct current transmission

International Journal of Electrochemical Science
The corrosion behavior of aluminum radiators in immersion solutions containing anion exchange resin (IRA), cation exchange resin (IRC), and mixed anion-cation exchange resin (IRM) from converter valve cooling systems in high-voltage direct current (HVDC)
Feng Wang, Xue Han, Liangshou Hao, Han Xu, Chaoyu Lei, Hong Xu, Jiayang Li, Yao Cheng, Shengping Wang   +8 more
doaj   +1 more source

A comparative study of ion exchange vs. ion pair chromatography for preparative separation of oligonucleotides

Oligonucleotides are commonly purified using either ion exchange chromatography (IEX) or ion-pair reversedphase liquid chromatography (IP-RPLC). This study compares the purification of a crude 20-mer oligonucleotide (ON) using both methods under ...
Thunberg, Linda, Fornstedt, Torgny, Unoson, Cecilia,, Samuelsson, Jörgen, Stavenhagen, Kathrin,, Borland, Kayla,, Unoson, Cecilia, Jora, Manasses, Samuelsson, Jörgen,, Stavenhagen, Kathrin, Stalberg, Olof,, Leek, Tomas, Jora, Manasses,, Borland, Kayla, Leek, Tomas,, Lesko, Marek, Stalberg, Olof, Enmark, Martin,, Lesko, Marek,, Thunberg, Linda,, Fornstedt, Torgny,, Enmark, Martin   +21 more
core   +1 more source