Results 131 to 140 of about 105,791 (260)

Ion-exchange chromatography, capillary isoelectric focusing, and capillary zone electrophoresis coupled to mass spectrometry for charge variant analysis of monoclonal antibodies. [PDF]

MAbs
Schairer J, Höchsmann A, Bauer B, Höfer V, Römer J, Neusüß C.   +5 more
europepmc   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

Advanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng, Zheyan Fang, Shuang Zhao, You‐en Zhang, Na Wu, Zhenyang Guo, Xin Zhong, Bixuan Jiang, Hongfei Xu, Hangnan Hong, Zhentao Zhang, Mukaddas Abdurahman, Xueting Yu, Jilong Geng, Xiansu Nie, Supuya Abuduwahapi, Dong Huang, Gang Zhao, Wenbin Zhang, Hao Lu, Li Shen, Xin Zhao, Zhaoyang Chen, Junjie Guo, Hongchao Zheng, Yue He, Sanwu Wu, Jiayin Peng, Jiawen Song, Xiao Wang, Haomin Li, Yuli Huang, Shengying Qin, Haojie Lu, Xiangdong Wang, Jianguo Zhao, Lei Huang, Yun Zhao, Peng Li, Junbo Ge, Hua Li   +40 more
wiley   +1 more source

An Automated and Precise Approach for the Determination of Azide Residue in Angiotensin II Receptor Blockers Using In Situ Matrix Elimination Ion Chromatography with Switching Strategy. [PDF]

Int J Mol Sci
Lou C, Pan S, Yu X, Zhang K, Zhang K, Zhu Y.   +5 more
europepmc   +1 more source

Lysosome‐Featured Cell Aggregate‐Released Extracellular Vesicles Regulate Iron Homeostasis and Alleviate Post‐Irradiation Endothelial Ferroptosis for Mandibular Regeneration

Advanced Science, EarlyView.
Lysosomal redistribution occurs via extracellular vesicles in multi‐stem cell aggregates and controls iron homeostasis for safeguarding cell aggregation. These cell aggregate‐released extracellular vesicles (CA‐EVs) rescue lysosomal impairments and exert anti‐ferroptosis effects in recipient irradiated endothelial cells.
Yuan‐Yuan Li, Bo Ma, Jia‐Wei Lu, Kai‐Chao Zhang, Chao Ma, Sheng‐Feng Bai, Yan‐Jiao Li, Si‐Qi Ying, Wei‐Zong Weng, Kai Zhang, Xi‐Wang Hu, Rang Li, Chen‐Xi Zheng, Xiao‐Ru Xu, Ji Chen, Fang Jin, Hao‐Kun Xu, Jian‐Wei Xie, Yan Jin, Yi Shuai, Bing‐Dong Sui   +20 more
wiley   +1 more source

Purification of bradykinin by ion-exchange chromatography [PDF]

Biochemical Journal, 1956
M. Rocha e Silva, Sylvia O. Andrade
openaire   +3 more sources

Robust and Reversible Supramolecular Adhesive via Dynamic Covalent Bond Crosslinking‐Induced Assembly of Metal‐Coordinated Nanoparticles

Advanced Science, EarlyView.
A supramolecular polymer network is constructed through the assembly of metal‐coordinated nanoparticles induced by the crosslinking of dynamic covalent disulfide bond. The resulting supramolecular adhesive exhibited excellent adhesion performance, including strong adhesion strength, exceptional solvent resistance, and distinct reversible adhesion ...
Yanyan Guo, Mengran Zhang, Shuanggen Wu, Xunqiu Wang   +3 more
wiley   +1 more source

Purification of Monoclonal Antibodies Using Chromatographic Methods: Increasing Purity and Recovery. [PDF]

Adv Pharm Bull
Jafarzadeh Chehraghi E, Akbarzadehlaleh P, Shamsasenjan K.   +2 more
europepmc   +1 more source

Bismuth Silicate Catalyst for Efficient Electrocatalytic CO2 Reduction and Electrolyte‐Free Formic Acid Production

Advanced Science, EarlyView.
Layered Bi2SiO5 is designed that electrochemically reconstructs into a highly active Bi@Bi2O2CO3 catalyst for CO2‐to‐formate conversion. The system operates efficiently over a wide operating range. Coupling with solid‐state electrolyte system enables continuous production of electrolyte‐free formic acid, simplifying separation and reducing energy ...
Ping Zhu, Xin‐Hao Cai, Cheng‐Cheng Huang, Ying Zhou, Na Chu, Zi‐Bo Jing, Wen‐Long Wang, Bilu Liu, Yong Jiang, Qian‐Yuan Wu   +9 more
wiley   +1 more source

Nanoflow Size Exclusion Chromatography-Native Mass Spectrometry of Intact Proteoforms and Protein Complexes. [PDF]

Anal Chem
Zhai Z, Holmark T, van der Zon AAM, Tseliou V, Mutti FG, Astefanei A, Gargano AFG.   +6 more
europepmc   +1 more source

Contribution of Prostaglandin E2‐Induced Neuronal Excitation to Drug Resistance in Glioblastoma Countered by a Novel Blood–Brain Barrier Crossing Celecoxib Derivative

Advanced Science, EarlyView.
Glioblastoma (GBM) is an aggressive brain cancer that often recurs and resists chemotherapy. This study found that a chemical called PGE2 causes surrounding brain cells (neurons) to become over‐excited, which makes GBM cells resistant to treatment. Researchers developed a new drug, “Compound 11,” which can cross into the brain and effectively block ...
Chih‐Jie Shen, Hsien‐Chung Chen, Chien‐Liang Lin, Amandeep Thakur, Raphael Onuku, I‐Chung Chen, Hao‐Yi Li, Kwang‐Yu Chang, Jian‐Ying Chuang, Wen‐Bin Yang, Hong‐Yi Lin, Yi‐Ru Shen, Jing‐Ping Liou, Wen‐Chang Chang, Tsung‐I Hsu   +14 more
wiley   +1 more source