Results 21 to 30 of about 432,155 (258)

Abnormal retention of s-triazine herbicides on porous graphitic carbon

Reviews in Analytical Chemistry, 2021
Porous graphitic carbon (PGC) is a widely used stationary phase for reversed-phase high-performance liquid chromatography (HPLC) that allows separation of structurally similar compounds retained in mixed form on a flat graphite surface. Such a stationary
Grinevich Oksana, Khesina Zoya, Buryak Alexey   +2 more
doaj   +1 more source

Development and Validation of a Novel LC-MS/MS Method for a TDM-Guided Personalization of HSCT Conditioning with High-Dose Busulfan in Children

Biomedicines, 2023
Personalization of busulfan (Bu) exposure via therapeutic drug monitoring (TDM) is recommended for patients treated with high-dose conditioning regimens.
Alessia Cafaro, Federica Pigliasco, Giammarco Baiardi, Sebastiano Barco, Manuela Stella, Roberto Bandettini, Francesca Mattioli, Maura Faraci, Giuliana Cangemi   +8 more
doaj   +1 more source

Early gas chromatography/mass spectrometry [PDF]

Journal of the American Society for Mass Spectrometry, 1993
Spectroscopy Laboratory, The Dow Chemical Company, Midland, Michigan, USA In December 1955 or thereabouts, the authors coupled a homemade gas chromatograph to a research time-of-flight mass spectrometer constructed by W. C. Wiley, I. H. McLaren, and D. B. Harrington.
Gohlke, Roland S., McLafferty, Fred W.
openaire   +2 more sources

A Preliminary Study to Determine the Hydrogen and Oxygen Isotopic Compositions of Natural and Bottled Water using High Sensitivity Isotope Ratio Mass Spectrometry [PDF]

Geo Data, 2021
In this study, we introduce the stable isotopic results of water using a recently installed high sensitivity isotope ratio mass spectrometry (HS-IRMS) system at the Korea Institute of Geoscience and Mineral Resources (KIGAM).
Hyeongseok Song, Hui Je Jo, Dongwoo Yang
doaj   +1 more source

Development of an Accurate Mass Retention Time Database for Untargeted Metabolomic Analysis and Its Application to Plasma and Urine Pediatric Samples

Molecules, 2021
Liquid-chromatography coupled to high resolution mass spectrometry (LC-HRMS) is currently the method of choice for untargeted metabolomic analysis. The availability of established protocols to achieve a high confidence identification of metabolites is ...
Chiara Lavarello, Sebastiano Barco, Martina Bartolucci, Isabella Panfoli, Emanuele Magi, Gino Tripodi, Andrea Petretto, Giuliana Cangemi   +7 more
doaj   +1 more source

Bioanalytical LC-QTOF/MS Method for a N-phenylpiperazine Derivate (LQFM05): An Anxiolytic- and Antidepressant-like Prototype Drug Applied to Pharmacokinetic and Biodistribution Studies

Pharmaceuticals, 2023
The LQFM05 is a prototype drug designed for treatment of psychiatric disorders, such as schizophrenia, exhibiting anxiolytic- and antidepressant-like (12 or 24 µmol/kg) effects in classical behavioral tests.
Ana Cláudia M. Ramos, Kênnia R. Rezende, Carolina M. Teixeira, Aline R. Fernandes, Heloa Santos, Rúbia Darc Machado, Ricardo Menegatti, Boniek G. Vaz, Andréa R. Chaves   +8 more
doaj   +1 more source

UHPLC-MS/MS Analysis of Cannabidiol and Its Metabolites in Serum of Patients with Resistant Epilepsy Treated with CBD Formulations

Pharmaceuticals, 2021
Cannabidiol (CBD) is a promising therapeutic agent with analgesic, myorelaxant, and anti-epileptic actions. Recently, a purified form of CBD (Epidiolex®) has been approved by the European Medicines Agency (EMA) for the treatment of two highly-refractory ...
Sara Malaca, Massimo Gottardi, Federica Pigliasco, Sebastiano Barco, Alessia Cafaro, Elisabetta Amadori, Antonella Riva, Martina Marcenaro, Pasquale Striano, Giuliana Cangemi, Roberta Pacifici, Simona Pichini, Francesco Paolo Busardò   +12 more
doaj   +1 more source

A new finding in the old Knoevenagel condensation reaction

Results in Chemistry, 2022
Reaction of benzaldehyde (5a) with defined quantities of ethyl cyanoacetate (6) in presence of piperidine was studied. In a neat condition, hexasubstituted cyclohexeneamine (7a) with three ester substituents was formed along with ethyl acrylate (9a ...
Attimogee Shivamurthy Harisha, Kuppuswamy Nagarajan, S.Saravanan, Venkat Manohar, Sajesh P. Thomas, Tayur Narasingarow Guru Row   +5 more
doaj   +1 more source

Cannabidiol Determination on Peripheral Capillary Blood Using a Microsampling Method and Ultra-High-Performance Liquid Chromatography Tandem Mass Spectrometry with On-Line Sample Preparation

Molecules, 2020
The aim of this work is to evaluate volumetric absorptive microsampling (VAMS) from capillary blood as an alternative strategy for therapeutic drug monitoring (TDM) in patients treated with the newly available GW-purified form of cannabidiol (Epidiolex®).
Federica Pigliasco, Sebastiano Barco, Sara Dubois, Francesca Marchese, Pasquale Striano, Tommaso Lomonaco, Francesca Mattioli, Gino Tripodi, Giuliana Cangemi   +8 more
doaj   +1 more source

Untargeted LC-HRMS Based-Plasma Metabolomics Reveals 3-O-Methyldopa as a New Biomarker of Poor Prognosis in High-Risk Neuroblastoma

Frontiers in Oncology, 2022
Neuroblastoma (NB) is the most common extracranial malignant tumor in children. Although the survival rate of NB has improved over the years, the outcome of NB still remains poor for over 30% of cases.
Sebastiano Barco, Chiara Lavarello, Davide Cangelosi, Martina Morini, Alessandra Eva, Luca Oneto, Paolo Uva, Gino Tripodi, Alberto Garaventa, Massimo Conte, Andrea Petretto, Giuliana Cangemi   +11 more
doaj   +1 more source