Results 21 to 30 of about 446,999 (263)

A Volumetric Absorptive Microsampling Technique to Monitor Cannabidiol Levels in Epilepsy Patients

Frontiers in Pharmacology, 2020
Purpose: Interest in cannabis-based therapies has recently increased, due to the availability of cannabidiol (CBD) for the treatment of epilepsy without psychoactive effects.
Sara Dubois, Francesca Marchese, Federica Pigliasco, Sebastiano Barco, Gino Tripodi, Tommaso Lomonaco, Simona Lattanzi, Emilio Russo, Giuliana Cangemi, Pasquale Striano, Pasquale Striano   +10 more
doaj   +1 more source

Evaluation of Antioxidant and Cytotoxic Activity of Hydro-Ethanolic Extracts Obtained from Steiractinia aspera Cuatrec

Molecules, 2022
In this work, the antioxidant activity of the hydro-ethanolic extracts of the leaves, flowers, and aerial parts of Steiractinia aspera Cuatrec, both fresh and post-distillation, was evaluated by ABTS+·, FRAP, H2O2 and DPPH assays.
Laura Gamboa-Carvajal, Carlos Jara-Gutiérrez, Joan Villena, Lautaro Taborga, Jairo René Martínez, Luis Espinoza, Elena E. Stashenko   +6 more
doaj   +1 more source

Development of a multiplex mass spectrometry method for simultaneous quantification of urinary proteins related to respiratory health

Scientific Reports, 2021
Respiratory health of children is a health priority. Club cell protein (CC16) is an interesting biomarker of lung diseases and adverse effects towards the airway epithelium integrity.
Sarah J. D. Nauwelaerts, Nancy H. C. Roosens, Alfred Bernard, Sigrid C. J. De Keersmaecker, Koen De Cremer   +4 more
doaj   +1 more source

Microbial Metabolomics with Gas Chromatography/Mass Spectrometry [PDF]

Analytical Chemistry, 2006
An analytical method was set up suitable for the analysis of microbial metabolomes, consisting of an oximation and silylation derivatization reaction and subsequent analysis by gas chromatography coupled to mass spectrometry. Microbial matrixes contain many compounds that potentially interfere with either the derivatization procedure or analysis, such ...
Koek, M.M., Muilwijk, B., Werf, M.J. van der, Hankemeier, T.   +3 more
openaire   +3 more sources

Untargeted Metabolomics for Unraveling the Metabolic Changes in Planktonic and Sessile Cells of Salmonella Enteritidis ATCC 13076 after Treatment with Lippia origanoides Essential Oil

Antibiotics, 2023
Nontyphoidal Salmonella species are one of the main bacterial causes of foodborne diseases, causing a public health problem. In addition, the ability to form biofilms, multiresistance to traditional drugs, and the absence of effective therapies against ...
Yuliany Guillín, Marlon Cáceres, Elena E. Stashenko, William Hidalgo, Claudia Ortiz   +4 more
doaj   +1 more source

Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method

Biomedicines, 2023
The new breakthrough cystic fibrosis (CF) drug combination of ivacaftor (IVA), tezacaftor (TEZ), and elexacaftor (ELX), namely “caftor” drugs, directly modulates the activity and trafficking of the defective CF transmembrane conductance regulator protein
Federica Pigliasco, Alessia Cafaro, Manuela Stella, Giammarco Baiardi, Sebastiano Barco, Nicoletta Pedemonte, Claudia D’Orsi, Federico Cresta, Rosaria Casciaro, Carlo Castellani, Maria Grazia Calevo, Francesca Mattioli, Giuliana Cangemi   +12 more
doaj   +1 more source

In Vitro and In Silico Analyses Explore the Role of Flavonoid Classes in the Antiviral Activity of Plant Extracts Against the Dengue Virus

Molecules
This study examined the relationship between flavonoid content and the antiviral effects of plant extracts against the dengue virus (DENV). Fourteen extracts from medicinal plants cultivated in Colombia, which were prepared by ultrasonic-assisted solvent
Sindi A. Velandia, Elena E. Stashenko, Elizabeth Quintero-Rueda, Sergio Conde-Ocazionez, Lady J. Sierra, Raquel E. Ocazionez   +5 more
doaj   +1 more source

Isotopic and Elemental Determination in Some Romanian Apple Fruit Juices

The Scientific World Journal, 2012
H, C, O stable isotope ratios and the content of some heavy elements of 31 Romanian single-strength organic apple juices collected from four Transylvanian areas are discussed in this study. The aim of this study was to measure the 2H/1H, 18O/16O, 13C/12C
Dana Alina Magdas, Adriana Dehelean, Romulus Puscas   +2 more
doaj   +1 more source

Bergenia Genus: Traditional Uses, Phytochemistry and Pharmacology

Molecules, 2020
Bergenia (Saxifragaceae) genus is native to central Asia and encompasses 32 known species. Among these, nine are of pharmacological relevance. In the Indian system of traditional medicine (Ayurveda), “Pashanabheda” (stone breaker) is an elite drug ...
Bhupendra Koul, Arvind Kumar, Dhananjay Yadav, Jun-O. Jin   +3 more
doaj   +1 more source

Gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry metabolomics platforms: Tools for plant oligosaccharides analysis

Carbohydrate Polymer Technologies and Applications, 2023
Oligosaccharides play a central role in plants and are involved in basal metabolism, and many other functions at cellular levels. Indeed, oligosaccharides analysis was stimulated by the development of analytical chemistry and computational biology and ...
Noureddine Benkeblia
doaj   +1 more source