Results 31 to 40 of about 3,985,069 (299)

Cluster secondary ion mass spectrometry microscope mode mass spectrometry imaging [PDF]

open access: yes, 2013
RATIONALE: Microscope mode imaging for secondary ion mass spectrometry is a technique with the promise of simultaneous high spatial resolution and high-speed imaging of biomolecules from complex surfaces.
Jungmann, JH   +6 more
core   +1 more source

Automated processing of whole blood samples for the determination of immunosuppressants by liquid chromatography tandem-mass spectrometry [PDF]

open access: yes, 2006
Background: Liquid chromatography tandem-mass spectrometry (LC-MS/MS) is an efficient technology for routine determination of immunosuppressants in whole blood; however, time-consuming manual sample preparation remains a significant limitation of this ...
Spöhrer, Ute, Vogeser, Michael
core   +1 more source

Development of a multiplex mass spectrometry method for simultaneous quantification of urinary proteins related to respiratory health

open access: yesScientific Reports, 2021
Respiratory health of children is a health priority. Club cell protein (CC16) is an interesting biomarker of lung diseases and adverse effects towards the airway epithelium integrity.
Sarah J. D. Nauwelaerts   +4 more
doaj   +1 more source

Solid phase extraction for removal of matrix effects in lipophilic marine toxin analysis by liquid chromatography-tandem mass spectrometry [PDF]

open access: yes, 2009
The potential of solid phase extraction (SPE) clean-up has been assessed to reduce matrix effects (signal suppression or enhancement) in the liquid chromatography-tandem mass spectrometry (LC¿MS/MS) analysis of lipophilic marine toxins.
Boer, J., de   +22 more
core   +2 more sources

Microbial Metabolomics with Gas Chromatography/Mass Spectrometry [PDF]

open access: yesAnalytical Chemistry, 2006
An analytical method was set up suitable for the analysis of microbial metabolomes, consisting of an oximation and silylation derivatization reaction and subsequent analysis by gas chromatography coupled to mass spectrometry. Microbial matrixes contain many compounds that potentially interfere with either the derivatization procedure or analysis, such ...
Koek, M.M.   +3 more
openaire   +3 more sources

Untargeted Metabolomics for Unraveling the Metabolic Changes in Planktonic and Sessile Cells of Salmonella Enteritidis ATCC 13076 after Treatment with Lippia origanoides Essential Oil

open access: yesAntibiotics, 2023
Nontyphoidal Salmonella species are one of the main bacterial causes of foodborne diseases, causing a public health problem. In addition, the ability to form biofilms, multiresistance to traditional drugs, and the absence of effective therapies against ...
Yuliany Guillín   +4 more
doaj   +1 more source

Simultaneous Quantification of Ivacaftor, Tezacaftor, and Elexacaftor in Cystic Fibrosis Patients’ Plasma by a Novel LC–MS/MS Method

open access: yesBiomedicines, 2023
The new breakthrough cystic fibrosis (CF) drug combination of ivacaftor (IVA), tezacaftor (TEZ), and elexacaftor (ELX), namely “caftor” drugs, directly modulates the activity and trafficking of the defective CF transmembrane conductance regulator protein
Federica Pigliasco   +12 more
doaj   +1 more source

Inter-laboratory reproducibility of fast gas chromatography-electron impact-time of flight mass spectrometry (GC-EI-TOF/MS) based plant metabolomics [PDF]

open access: yes, 2009
The application of gas chromatography¿mass spectrometry (GC¿MS) to the `global¿ analysis of metabolites in complex samples (i.e. metabolomics) has now become routine.
Dunn, Warwick   +38 more
core   +1 more source

Performing native mass spectrometry analysis on therapeutic antibodies [PDF]

open access: yes, 2013
Since the introduction of “soft” ionization techniques, the role of mass spectrometry (MS) in the field of structural biology has increasingly expanded.
Heck, A.J.R.   +4 more
core   +1 more source

Gas chromatography-mass spectrometry and liquid chromatography-mass spectrometry metabolomics platforms: Tools for plant oligosaccharides analysis

open access: yesCarbohydrate Polymer Technologies and Applications, 2023
Oligosaccharides play a central role in plants and are involved in basal metabolism, and many other functions at cellular levels. Indeed, oligosaccharides analysis was stimulated by the development of analytical chemistry and computational biology and ...
Noureddine Benkeblia
doaj   +1 more source

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