Results 21 to 30 of about 30,456 (242)
Genetic background influences tumour development in heterozygous Men1 knockout mice [PDF]
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreatic and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroidism (FIHP)
Christie, Paul T. +11 more
core +2 more sources
Analysis of thyroid carcinomas with immunohistochemical panel application: retrospectively study of 52 cases [PDF]
Aim: The aim of this study was to share our cases of thyroid carcinoma with the literature and to emphasize the importance of evaluation with an immunohistochemical panel in cases with difficulty in the differential diagnosis.
Mecdi Gurhan Balci, Mahir Tayfur
doaj +1 more source
The surging role of Chromogranin A in cardiovascular homeostasis
Together with Chromogranin B and Secretogranins, Chromogranin A (CGA) is stored in secretory (chromaffin) granules of the diffuse neuroendocrine system and released with noradrenalin and adrenalin.
BRUNO eTOTA +2 more
doaj +1 more source
Background Abdominal nonfunctional paraganglioma is rare. Malignant potential of paraganglioma is assessed by Grading of Adrenal Pheochromocytoma and Paraganglioma score and genetic testing, but genetic testing is not common.
Takazo Tanaka +8 more
doaj +1 more source
Non-functional duodenal neuroendocrine carcinoma: a rare cause of diabetes mellitus
A 40-year-old Caucasian female presented with hyperglycaemia, polyuria, polydipsia and weight loss of 6 kg over a 1-month period. There was no personal or family history of malignancy or diabetes mellitus.
Chad Bisambar +3 more
doaj +1 more source
FGFR2 amplification in colorectal adenocarcinoma [PDF]
FGFR2 is recurrently amplified in 5% of gastric cancers and 1%–4% of breast cancers; however, this molecular alteration has never been reported in a primary colorectal cancer specimen.
Carter, Jamal H +6 more
core +2 more sources
Duodenal neuroendocrine tumor and the onset of severe diabetes mellitus in a US veteran
Objective: Neuroendocrine tumors are neoplasms derived from endocrine cells, most commonly occurring in the gastrointestinal tract. Duodenal neuroendocrine tumors are rare tumors averaging 1.2–1.5 cm, and most are asymptomatic.
Lauren Murray +3 more
doaj +1 more source
Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H. +10 more
core +1 more source
Chromogranin A, chromogranin B/secretogranin I and chromogranin C/secretogranin II are acidic sulphated and phosphorylated secretory proteins present in a large number of endocrine and neuronal tissues. It has been suggested that these proteins may be useful immunohistochemical markers for human tumours of endocrine origin and their measurement in ...
Micaela Pelagi +11 more
openaire +2 more sources
Chromogranin B in Heart Failure [PDF]
Background— Chromogranin B (CgB) is a member of the granin protein family. Because CgB is often colocalized with chromogranin A (CgA), a recently discovered cardiac biomarker, we hypothesized that CgB is regulated during heart failure (HF) development. Methods and Results—
Helge, Røsjø +9 more
openaire +2 more sources

