Results 1 to 10 of about 12,444 (248)

2-(2-Phenylethyl)chromones increase in Aquilaria sinensis with the formation of agarwood [PDF]

Frontiers in Plant Science
Obtained from Aquilaria Lam. and Gyrinops Gaertn., agarwood is a prestigious perfume and medicinal material in the world. Its primary chemical constituents and indicators of agarwood's development are 2-(2-phenylethyl)chromones (PECs).
Yuanyuan Sun, Yuanyuan Sun, Meiran Wang, Meng Yu, Jian Feng, Jianhe Wei, Jianhe Wei, Yangyang Liu, Yangyang Liu   +8 more
doaj   +3 more sources

Rhodaelectro-catalyzed access to chromones via formyl C–H activation towards peptide electro-labeling

Nature Communications, 2021
The chromone scaffold is present in drugs and bioactive natural products, but conventional approaches to access chromones require stoichiometric amounts of oxidants. Here, the authors report rhodaelectro-catalyzed assembly of chromones by electrochemical
Maximilian Stangier, Antonis M. Messinis, João C. A. Oliveira, Hao Yu, Lutz Ackermann   +4 more
doaj   +2 more sources

A Concise Review of the Recent Structural Explorations of Chromones as MAO-B Inhibitors: Update from 2017 to 2023

Pharmaceuticals, 2023
Monoamine oxidases (MAOs) are a family of flavin adenine dinucleotide-dependent enzymes that catalyze the oxidative deamination of a wide range of endogenous and exogenous amines.
Reshma Susan Ipe, Sunil Kumar, Feba Benny, Jayalakshmi Jayan, Amritha Manoharan, Sachitra Thazhathuveedu Sudevan, Ginson George, Prashant Gahtori, Hoon Kim, Bijo Mathew   +9 more
doaj   +2 more sources

Indole Alkaloids and Chromones from the Stem Bark of Cassia alata and Their Antiviral Activities

Molecules, 2022
The Cassia (Leguminosae) genus has attracted a lot of attention as a prolific source of alkaloids and chromones with diverse structures and biological properties. The aim of this study is to screen the antiviral compounds from Cassia alata.
Pei-Song Yang, Jia-Meng Dai, Xue-Jiao Gu, Wen Xiong, De-Quan Huang, Shi-Yu Qiu, Jun-Na Zheng, Yong Li, Feng-Xian Yang, Min Zhou   +9 more
doaj   +2 more sources

Repositioning Chromones for Early Anti-inflammatory Treatment of COVID-19

Frontiers in Pharmacology, 2020
The COVID-19 pandemic is posing an unprecedented sanitary threat. In the absence of specific vaccines and anti-SARS-CoV-2 drugs, medicines that may assist in tackling the emergency and limiting the high number of fatalities are urgently needed.
Piero Sestili, Vilberto Stocchi
doaj   +2 more sources

Biological and Medicinal Properties of Natural Chromones and Chromanones. [PDF]

ACS Omega
Emerging threats to human health require a concerted effort to search for new treatment therapies. One of the biggest challenges is finding medicines with few or no side effects.
Gaspar A, Garrido EMPJ, Borges F, Garrido JMPJ.   +3 more
europepmc   +2 more sources

Identification of a diarylpentanoid-producing polyketide synthase revealing an unusual biosynthetic pathway of 2-(2-phenylethyl)chromones in agarwood

Nature Communications, 2022
2-(2-Phenylethyl)chromones (PECs) contribute to the distinctive fragrance of agarwood. Here the authors identify a diarylpentanoid-producing polyketide synthase from Aquilaria sinensis and show how it catalyzes PEC formation.
Xiao-Hui Wang, Bo-Wen Gao, Yu Nakashima, Takahiro Mori, Zhong-Xiu Zhang, Takeshi Kodama, Yuan-E Lee, Ze-Kun Zhang, Chin-Piow Wong, Qian-Qian Liu, Bo-Wen Qi, Juan Wang, Jun Li, Xiao Liu, Ikuro Abe, Hiroyuki Morita, Peng-Fei Tu, She-Po Shi   +17 more
doaj   +2 more sources

Comparison of the Blood–Brain Barrier Penetration Ability and Anti-Neuroinflammatory Activity of Chromones in Two Types of Agarwood [PDF]

Pharmaceuticals
Background/Objectives: Agarwood has a good neuroprotective effect and is often used to relieve anxiety and treat insomnia. This study compared the similarities and differences in the chromone components of two types of agarwood.
Mengyuan Yang, Yanan Yuan, Jingfan Wei, Yifei Pei, Yuanfei Niu, Yifan Zhao, Xiangying Kong, Zhijie Zhang   +7 more
doaj   +2 more sources

Dynamic Environmental Interactions Shape the Volatile Compounds of Agarwood Oils Extracted from Aquilaria sinensis Using Supercritical Carbon Dioxide [PDF]

Molecules
Aquilaria spp. are a highly valuable plant species found in the Chinese herbal medicine and agarwood fragrance supplement industries for fumigation, combustion and perfume.
Wenxian Zhang, Sizhu Qian, Dehuai Wu, Qiaoling Yan, Jen-Ping Chung, Yongmei Jiang   +5 more
doaj   +2 more sources

Two New Chromone Derivatives from a Marine Algicolous Fungus Aspergillus versicolor GXIMD 02518 and Their Osteoclastogenesis Inhibitory Activity [PDF]

Marine Drugs
Two new chromone derivatives, cnidimols I and J (1 and 2), together with ten known aromatic derivatives (3–12), were isolated from the Beibu Gulf algicolous fungus Aspergillus versicolor GXIMD 02518.
Xin Qi, Zhen Li, Miaoping Lin, Humu Lu, Shuai Peng, Huangxue Qin, Yonghong Liu, Chenghai Gao, Xiaowei Luo   +8 more
doaj   +2 more sources