Results 31 to 40 of about 12,444 (248)

An overview of 2-Styrylchromones: natural occurrence, synthesis, reactivity and biological properties [PDF]

, 2017
2-Styrylchromones are a small class of oxygen-containing heterocycles. Despite their sparse occurrence in nature, several synthetic approaches have been developed in order to synthesize a large variety of derivatives, possessing different substituents ...
Alonso, Ayyangar, Aziz, Baker, Baptista, Barros, Barros, Bennett, Berar, Bhattacharyya, Cavaleiro, Chaniad, Cheema, Clarke, Conti, Dean, Desideri, Desideri, Dhoubhadel, Doria, Elkashef, Fernandes, Fernandes, Ferreira, Filipe, Fuchigami, Fuchigami, Gaggad, Gaspar, Gerwick, Gerwick, Goel, Gomes, Gomes, Gomes, Gomes, Gomes, Gulati, Gupta, Gupta, Helibron, Hercouet, Jain, Jung, Karton, Kelkar, Keri, Kumar, Kumar, Königs, Lee, Letcher, Letcher, Letcher, Lin, Mahal, Makrandi, Makrandi, Marinho, Marini-Bettòlo, Marona, McGarry, Momin, Momin, Momoi, Mustafa, Nam, Nikam, Obrecht, Ono, Paparao, Patoilo, Patoilo, Pawar, Peixoto, Pereira, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Pinto, Price, Reddy, Reddy, Robinson, Santos, Santos, Santos, Santos, Santos, Saraf, Schonberg, Sharma, Sharma, Shaw, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Silva, Singhi, Sousa, Sousa, Takamatsu, Talhi, Tawfik, Yang, Yang, Yokoe, Yoon, Zammattio, Zammattio, Zammattio   +122 more
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Characterization of Potent ABCG2 Inhibitor Derived from Chromone: From the Mechanism of Inhibition to Human Extracellular Vesicles for Drug Delivery

Pharmaceutics, 2023
Inhibition of ABC transporters is a promising approach to overcome multidrug resistance in cancer. Herein, we report the characterization of a potent ABCG2 inhibitor, namely, chromone 4a (C4a).
Glaucio Valdameri, Diogo Henrique Kita, Julia de Paula Dutra, Diego Lima Gomes, Arun Kumar Tonduru, Thales Kronenberger, Bruno Gavinho, Izadora Volpato Rossi, Mariana Mazetto de Carvalho, Basile Pérès, Ingrid Fatima Zattoni, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Rilton Alves de Freitas, Antti Poso, Suresh V. Ambudkar, Marcel I. Ramirez, Ahcène Boumendjel, Vivian Rotuno Moure   +18 more
doaj   +1 more source

Novel chromone and xanthone derivatives: synthesis and ROS/RNS scavenging activities [PDF]

, 2016
Chromones and xanthones are oxygen-containing heterocyclic compounds acknowledged by their antioxidant properties. In an effort to develop novel agents with improved activity, a series of compounds belonging to these chemical classes were prepared. Their
Albuquerque, Hélio, Fernandes, Eduarda, Freitas, Marisa, Proença, Carina, Ribeiro, Daniela, Santos, Clementina M.M., Silva, Artur   +6 more
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Antinociceptive effects of intrathecal cimifugin treatment: a preliminary rat study based on formalin test [PDF]

Anesthesia and Pain Medicine, 2020
Background Cimifugin is one of the components of the root of Saposhnikovia divaricata. The extract derived from S. divaricata is traditionally used as an analgesic. This study was conducted to evaluate the analgesic effect of intrathecal cimifugin in the
Hyun Young Lee, Young Joon Ki, Su Yeong Park, Soo Yeon Cho, Jinyoung Seo, Kyung Joon Lim, Ki Tae Jung   +6 more
doaj   +1 more source

(E)-2-(4-Arylbut-1-en-3-yn-1-yl)chromones as synthons for the synthesis of xanthone-1,2,3-triazole dyads [PDF]

, 2015
Xanthone-1,2,3-triazole dyads have been synthesized by two different approaches, both starting from novel (E)-2-(4-arylbut-1-en-3-yn-1-yl)chromones, prepared through a base-catalyzed aldol reaction of 2-methylchromone and arylpropargyl aldehydes.
Alexacou, Arikan, Baker, Bennett, Chandrasekar, da Silva, Ee, El-Seedi, Esteves, Fan, Freitas, Genin, Herbrecht, Jiang, Kelkar, Khan, Kotha, Letcher, Letcher, Li, Mahal, Massarotti, Na, Oldenburg, Park, Pinto, Portela, Pothitirat, Price, Riscoe, Sakai, Santos, Silva, Silva, Silva, Sonogashira, Tretyakov, Vieira, Wadsworth, Zou   +39 more
core   +1 more source

6-tert-Butyl-4-[(4-hydroxymethyl-2H-1,2,3-triazol-2-yl)methyl]-2H-chromen-2-one

IUCrData, 2016
In the title compound, C17H19N3O3, the triazole ring and the chromene ring system [maximum deviation = 0.018 (2) Å for the O atom] bridged via a methylene C atom, are inclined to one another by 73.2 (1)°.
Nasseem El-Khatatneh, Chandra, D. Shamala, K. Shivashankar, M. Mahendra   +4 more
doaj   +1 more source

New insights in the discovery of novel h-MAO-B inhibitors: structural characterization of a series of N-phenyl-4-oxo-4H-chromene-3-carboxamide derivatives

Acta Crystallographica Section E: Crystallographic Communications, 2015
Six N-substituted-phenyl 4-oxo-4H-chromene-3-carboxamides, namely N-(2-nitrophenyl)-4-oxo-4H-chromene-3-carboxamide, C16H10N2O5 (2b), N-(3-methoxyphenyl)-4-oxo-4H-chromene-3-carboxamide, C17H13NO4, (3a), N-(3-bromophenyl)-4-oxo-4H-chromene-3-carboxamide,
Ligia R. Gomes, John Nicolson Low, Fernando Cagide, Daniel Chavarria, Fernanda Borges   +4 more
doaj   +1 more source

Analysis of Antioxidant Capacity of Chromones in Saposhnikoviae Radix Obtained by Ultrasonic-Assisted Deep Eutectic Solvents Extraction

Journal of Analytical Methods in Chemistry, 2020
In this paper, ultrasonic-assisted deep eutectic solvent (DES) extraction was applied to the acquisition of chromones (cimicifugin, prim-o-glucosylcimifugin, and 5-o-methylvisamminoside) from Saposhnikoviae radix (SR).
Xianwen Yue, Fangfei Xu, Peng Lv, Huailei Yang, Huiwei Bao, Yang Xu   +5 more
doaj   +1 more source

1,6-Conjugate Additions of Carbon Nucleophiles to 2-[(1E,3E)-4-Arylbuta-1,3-dien-1-yl]-4H-chromen-4-ones [PDF]

, 2017
KGaA, Weinheim The 1,6-conjugate addition of nitromethane to 2-[(1E,3E)-4-arylbuta-1,3-dien-1-yl]-4H-chromen-4-ones was accomplished and led mainly to the corresponding β-(nitromethyl)chromones. (E)-5′-(Nitromethyl)-3′-styryl-[1,1′-biphenyl] -2-ol and 3′-
, Albuquerque, Albuquerque, Albuquerque, Ballini, Bernini, Cardona, Csákÿ, Esteves, Ferreira, Gaspar, Giardinetti, Grünenfelder, Gu, Guo, Hajra, Ibrahim, Kawai, Keri, Lee, Lippur, Liu, Liu, Matsuda, Mei, Nakashima, Oliva, Pinto, Pinto, Pinto, Prakash, Proença, Punyapreddiwar, Resende, Santos, Silva, Silva, Silva, Sousa, Sousa, Talhi, Vakulya, Yadav, Zhu   +43 more
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Tetrahydroquinazoline-substituted chromones from Diels–Alder reaction of (E)-2-styrylchromones and pyrimidine ortho-quinodimethane [PDF]

, 2012
The Diels-Alder reaction of (E)-2-styrylchromones with a pyrimidine ortho-quinodimethane is reported for the first time. These cycloaddition reactions afford mixtures of two regioisomeric tetrahydroquinazoline-substituted chromones in moderate to ...
Cavaleiro, José, Patoilo, Diana, Pinto, Diana, Santos, Clementina M.M., Silva, Artur, Tomé, Augusto   +5 more
core   +1 more source