Results 161 to 170 of about 119,383 (327)

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Chromosomal Aberrations, Micronuclei, Blood Parameters and Received Doses in Workers Exposed to Ionizing Radiation. [PDF]

Med Lav, 2023
Djokovic J, Jankovic S, Milovanovic A, Bulat P.   +3 more
europepmc   +1 more source

Proliferative behaviour and cytogenetic changes in human renal-cell carcinoma [PDF]

, 1991
Allhoff, E. P., Azpodien, J., Djamilian, Mohamad H., Jonas, Udo, Kirchner, H., Riese, W. de, Schlick, R. W., Stief, Christian Georg, Werner, M.   +8 more
core   +1 more source

AB0184 Chromosomal aberrations are associated with disease severity in a mouse model of bleomycin-induced scleroderma [PDF]

, 2017
Roberto Luisetto, Marianna Beggio, Anna Scanu, Felipe Leite de Oliveira, Erika Pigatto, Antonella Peruffo, Elisabetta Zanatta, Francesca Oliviero, Paolo Sfriso, Leonardo Punzi, Franco Cozzi   +10 more
openalex   +1 more source

BCR::ABL1‐Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B‐ALL Cells to Enhancer‐Targeting Drugs

Advanced Science, EarlyView.
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng, Trudy Lee Glaser, Jintao Zhu, Mark E. Robinson, Kadriye N. Cosgun, Valeriya Malysheva, Ozgen Deniz, Nicholas T. Crump, Kaiyue Helian, Andrew J. Innes, Richard Burt, Li Sun, George John, Haibin Zhou, Atsunori Kaneshige, Longchuan Bai, Shaomeng Wang, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn   +19 more
wiley   +1 more source

Chromosomal Aberrations in Cattle. [PDF]

Genes (Basel), 2021
Holečková B, Schwarzbacherová V, Galdíková M, Koleničová S, Halušková J, Staničová J, Verebová V, Jutková A.   +7 more
europepmc   +1 more source

Exposure of Tradescantia Microspores to Periodic Vibrations of 40-100 Hertz [PDF]

Spherical chromosomal fragments determined in exposure of Tradescantia microspores to periodic ...
Bales, L. J., Knepton, J. C., Jr.
core   +1 more source

Body composition and blood pressure in 6-year-old singletons born after pre-implantation genetic testing for monogenic and structural chromosomal aberrations: a matched cohort study [PDF]

, 2018
Florence Belva, Mathieu Roelants, Salome Adriana Kluijfhout, C. Winter, F. De Schrijver, S. Desmyttere, Martine De Rycke, Herman Tournaye, I. Liebærs, M Bonduelle   +9 more
openalex   +1 more source

NanoLoop: A Deep Learning Framework Leveraging Nanopore Sequencing for Chromatin Loop Prediction

Advanced Science, EarlyView.
Chromatin loops are central to gene regulation and 3D genome organization. Leveraging Nanopore sequencing's ability to jointly capture DNA sequence and methylation, we present NanoLoop, the first framework for genome‐wide chromatin loop prediction using Nanopore data.
Wenjie Huang, Li Tang, Matthew C. Hill, Yonghao Zhang, Jun Xie, Min Li   +5 more
wiley   +1 more source

STUDY OF GENOTOXICITY OF ENVIRONMENTAL CHEMICAL POLLUTION ON TWO SPECIES OF GENUS APODEMUS (RODENTIA MAMMALIA)

Iranian Journal of Public Health, 1998
In present work, genotoxicological effects of chemical pollution of an industrial region, on species of genus Apodemus (Rodentia, Mammalia), were studied. The two species were A.flavicolis and A.agrarius.
H. Pour-Jafari, D.D. Farhud, A.R. Mesdaghinia   +2 more
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