Results 31 to 40 of about 824,606 (327)

In vivo genotoxicity assessment of titanium dioxide nanoparticles by Allium cepa root tip assay at high exposure concentrations. [PDF]

PLoS ONE, 2014
The industrial production and commercial applications of titanium dioxide nanoparticles have increased considerably in recent times, which has increased the probability of environmental contamination with these agents and their adverse effects on living ...
Sunandan Pakrashi, Nitin Jain, Swayamprava Dalai, Jerobin Jayakumar, Prathna Thanjavur Chandrasekaran, Ashok M Raichur, Natarajan Chandrasekaran, Amitava Mukherjee   +7 more
doaj   +1 more source

An integrative CGH, MSI and candidate genes methylation analysis of colorectal tumors. [PDF]

PLoS ONE, 2014
Different DNA aberrations processes can cause colorectal cancer (CRC). Herein, we conducted a comprehensive molecular characterization of 27 CRCs from Iranian patients.Array CGH was performed.
Hassan Brim, Mones S Abu-Asab, Mehdi Nouraie, Jose Salazar, Jim Deleo, Hadi Razjouyan, Pooneh Mokarram, Alejandro A Schaffer, Fakhraddin Naghibhossaini, Hassan Ashktorab   +9 more
doaj   +1 more source

Molecular responses and chromosomal aberrations in patients with polycythemia vera treated with peg-proline-interferon alpha-2b

American journal of hematology/oncology, 2015
Fifty‐one polycythemia vera (PV) patients were enrolled in the phase I/II clinical study PEGINVERA to receive a new formulation of pegylated interferon alpha (peg‐proline‐IFNα‐2b, AOP2014/P1101).
Nicole C. C. Them, K. Bagienski, T. Berg, B. Gisslinger, M. Schalling, Doris Chen, V. Buxhofer-Ausch, J. Thaler, E. Schloegl, G. Gastl, D. Wolf, K. Strecker, A. Egle, T. Melchardt, S. Burgstaller, E. Willenbacher, O. Zagrijtschuk, C. Klade, R. Greil, H. Gisslinger, R. Kralovics   +20 more
semanticscholar   +1 more source

Radiation-induced chromosomal aberrations in grape Phylloxera

Advances in Horticultural Science, 2013
Chromosomal aberrations in phylloxera females induced by different doses of gamma irradiation were detected. The results showed that the chromosomes of all tested embryos of irradiated phylloxera had aberrations, regardless of dose.
H. Makee, N. Tafesh, I. Idris
doaj   +1 more source

HPV type-related chromosomal profiles in high-grade cervical intraepithelial neoplasia

BMC Cancer, 2012
Background The development of cervical cancer and its high-grade precursor lesions (Cervical Intraepithelial Neoplasia grade 2/3 [CIN2/3]) result from a persistent infection with high-risk human papillomavirus (hrHPV) types and the accumulation of (epi ...
Bierkens Mariska, Wilting Saskia M, van Wieringen Wessel N, van de Wiel Mark A, Ylstra Bauke, Meijer Chris JLM, Snijders Peter JF, Steenbergen Renske DM   +7 more
doaj   +1 more source

DNA breaks and chromosomal aberrations arise when replication meets base excision repair

Journal of Cell Biology, 2014
DNA double-strand breaks and chromosomal aberrations after treatment with N-alkylating agents likely arise as a result of replication fork collision with single-strand breaks generated during base excision repair.
M. Ensminger, Lucie Iloff, Christian Ebel, T. Nikolova, B. Kaina, Markus Lӧbrich   +5 more
semanticscholar   +1 more source

Correlation between Cytogenetic Findings and Spermatogenic Failure in Bulgarian Infertile Men

Life, 2022
The aim of our study was to determine the type and frequency of chromosomal aberrations and polymorphisms in men with different degrees of spermatogenic failure in comparison to men with normozoospermia, in order to find correlations between cytogenetic ...
Svetlana Yovinska, Kalina Belemezova, Mariela Hristova-Savova, Tanya Milachich, Petya Andreeva, Lachezara Veleva, Yuri Buchvarov, Maria Yunakova, Tanya Timeva, Atanas Shterev, Ivanka Dimova   +10 more
doaj   +1 more source

Deciphering the pathogenic consequences of chromosomal aberrations in human genetic disease

Molecular Cytogenetics, 2014
Chromosomal aberrations include translocations, deletions, duplications, inversions, aneuploidies and complex rearrangements. They underlie genetic disease in roughly 15% of patients with multiple congenital abnormalities and/or mental retardation (MCA ...
W. Kloosterman, R. Hochstenbach
semanticscholar   +1 more source

Chromosomal aberrations and their prognostic value in a series of 174 untreated patients with Waldenström's macroglobulinemia

Haematologica, 2013
Waldenström's macroglobulinemia is a disease of mature B cells, the genetic basis of which is poorly understood. Few recurrent chromosomal abnormalities have been reported, and their prognostic value is not known.
F. Nguyen‐Khac, J. Lambert, E. Chapiro, A. Grelier, S. Mould, C. Barin, A. Daudignon, N. Gachard, S. Struski, C. Henry, D. Penther, H. Mossafa, J. Andrieux, V. Eclache, C. Bilhou-Nabera, I. Luquet, C. Terré, L. Baranger, F. Mugneret, J. Chiésa, M. Mozziconacci, E. Callet‐Bauchu, L. Véronèse, H. Blons, R. Owen, J. Lejeune, S. Chevret, H. Merle-Béral, V. Leblond   +28 more
semanticscholar   +1 more source

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

FEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino, Meijie Li, Cécile Fizames, Mattia Adamo, Laurence Lejay, Christian Dubos, Matthieu Platre, Antoine Martin   +7 more
wiley   +1 more source