Results 41 to 50 of about 267,700 (194)
Insects, 2011 Chromosomal rearrangements can alter the rate and patterns of gene flow within or between species through a reduction in the fitness of chromosomal hybrids or by reducing recombination rates in rearranged areas of the genome.
Steven J. B. Cooper +2 more
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Common Chromosomal Fragile Sites: Breakages and Rearrangements in Somatic and Germline Cells [PDF]
, 2011 Deep insight on Common Chromosomal Fragile Sites: Breakages and Rearrangements in Somatic and Germline ...
Mitsui, J, Tsuji, S
core +1 more source
Microorganisms, 2022 The Cre-loxP system produces structural variations, such as deletion, duplication, inversion and translocation, at specific loci and induces chromosomal rearrangements in the genome.
Haiyan Ren +6 more
doaj +1 more source
The Extent and Nature Of Chromosomal Rearrangements in B Lymphocytes [PDF]
, 2012 Chromosomal rearrangements, including translocations, require formation and joining of DNA double strand breaks (DSBs). These events disrupt the integrity of the genome and are frequently involved in producing leukemias, lymphomas and sarcomas.
Klein, Isaac Andrew
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, 2013 Percentage of cells displaying chromosomal rearrangements including dicentric chromosome formation (A) and complex rearrangements (B). The effects were investigated in SCC61, SQ20B, and DMF/BSO (TTT)-treated SQ20B cell lines after 10 Gy of X-ray or 5 Gy ...
Thierry Douki (298019) +8 more
core +1 more source
Chromosomal rearrangements in chondromatous tumors [PDF]
Cancer, 1990 Short-term cultures from 16 chondromatous tumors, 15 primary and one recurrent, were analyzed cytogenetically. Clonal chromosome aberrations were found in one of six benign tumors and in seven of ten malignant tumors. A chondroma had a complex translocation involving chromosomes X, 8, 12, and 13, as well as a deletion of the derivative chromosome 8. In
N, Mandahl +5 more
openaire +2 more sources
Chromosomal rearrangements and karyotype evolution in carnivores revealed by chromosome painting
, 2011 Chromosomal evolution in carnivores has been revisited extensively using cross-species chromosome painting. Painting probes derived from flow-sorted chromosomes of the domestic dog, which has one of the most rearranged karyotypes in mammals and the ...
Perelman, P. L. +16 more
core +1 more source
PLoS ONE, 2018 The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis-a low-resolution genome-wide chromosome analysis-is still the gold standard, it often needs to be complemented with ...
Anh Nhi Tran +10 more
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Fusion Genes and RNAs in Cancer Development
Non-Coding RNA, 2021 Fusion RNAs are a hallmark of some cancers. They result either from chromosomal rearrangements or from splicing mechanisms that are non-chromosomal rearrangements.
Kenzui Taniue, Nobuyoshi Akimitsu
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Constitutional balanced chromosomal rearrangements and neoplasm in children.
, 2001 A predisposition to tumor development is currently associated with some, but not all, constitutional chromosomal abnormalities. In a series of 578 children, in which conventional cytogenetic investigation was performed on material from various benign and
Niggli FK +4 more
core +1 more source