Results 41 to 50 of about 1,114,920 (242)

Interstitial deletion 4p15.32p16.1 and complex chromoplexy in a female proband with severe neurodevelopmental delay, growth failure and dysmorphism

Molecular Cytogenetics, 2022
Complex chromosomal rearrangements involve the restructuring of genetic material within a single chromosome or across multiple chromosomes. These events can cause serious human disease by disrupting coding DNA and gene regulatory elements via deletions ...
Dong Li, Alanna Strong, Cuiping Hou, Helen Downes, Amanda Barone Pritchard, Pamela Mazzeo, Elaine H. Zackai, Laura K. Conlin, Hakon Hakonarson   +8 more
doaj   +1 more source

Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements [PDF]

, 2003
The mouse has evolved to be the primary mammalian genetic model organism. Important applications include the modeling of human cancer and cloning experiments. In both settings, a detailed analysis of the mouse genome is essential.
Geigl, J., Jentsch, I., Klein, C. A., Speicher, M. R.   +3 more
core   +1 more source

Gross Chromosomal Rearrangement at Centromeres

Biomolecules, 2023
Centromeres play essential roles in the faithful segregation of chromosomes. CENP-A, the centromere-specific histone H3 variant, and heterochromatin characterized by di- or tri-methylation of histone H3 9th lysine (H3K9) are the hallmarks of centromere chromatin.
Ran Xu, Ziyi Pan, Takuro Nakagawa
openaire   +3 more sources

Comparative studies of X chromosomes in Cervidae family

Scientific Reports, 2023
The family Cervidae is the second most diverse in the infraorder Pecora and is characterized by variability in the diploid chromosome numbers among species.
Anastasia A. Proskuryakova, Ekaterina S. Ivanova, Alexey I. Makunin, Denis M. Larkin, Malcolm A. Ferguson-Smith, Fengtang Yang, Olga V. Uphyrkina, Polina L. Perelman, Alexander S. Graphodatsky   +8 more
doaj   +1 more source

Neoantigenic Potential of Complex Chromosomal Rearrangements in Mesothelioma

Journal of Thoracic Oncology, 2019
Introduction: Malignant pleural mesothelioma is a disease primarily associated with exposure to the carcinogen asbestos. Whereas other carcinogen‐related tumors are associated with a high tumor mutation burden, mesothelioma is not.
A. Mansfield, T. Peikert, J. Smadbeck, J. Udell, E. Garcia-Rivera, Laura R. Elsbernd, C. Erskine, V. V. Van Keulen, F. Kosari, S. Murphy, Hongzheng Ren, Vishnu Serla, Janet L. Schaefer Klein, Giannoula Karagouga, F. Harris, Carlos P. Sosa, Sarah H. Johnson, W. Nevala, S. Markovic, A. Bungum, E. Edell, Haidong Dong, J. Cheville, M. Aubry, J. Jen, G. Vasmatzis   +25 more
semanticscholar   +1 more source

The Role of RNA in DNA Breaks, Repair and Chromosomal Rearrangements

Biomolecules, 2021
Incorrect reparation of DNA double-strand breaks (DSB) leading to chromosomal rearrangements is one of oncogenesis’s primary causes. Recently published data elucidate the key role of various types of RNA in DSB formation, recognition and repair.
Matvey Mikhailovich Murashko, Ekaterina Mikhailovna Stasevich, Anton Markovich Schwartz, Dmitriy Vladimirovich Kuprash, Aksinya Nicolaevna Uvarova, Denis Eriksonovich Demin   +5 more
doaj   +1 more source

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Anna Jauch, Bickmore, Cremer, Cremer, de Grouchy, Dutrillaux, Holmquist, Johannes Wienberg, Lalley, Lichter, Lichter, Lichter, O'Brien, Ohno, Pinkel, Roscoe Stanyon, Seuánez, Stanyon, Thomas Cremer, Van Dilla, Weber, Wienberg, Yunis   +22 more
core   +1 more source

MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas [PDF]

, 2006
In view of the certain anatomic site-dependent frequency of chromosomal translocations involved in extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) pathogenesis, 17 salivary gland MALT lymphoma cases were ...
Isaacson PG, Harris NL, Carbone A, Banham A, Streubel B, Ventura RA, Remstein ED, Baens M, Ye H   +8 more
core   +1 more source

Comparative cytogenetics in three species of Wood-Warblers (Aves: Passeriformes: Parulidae) reveal divergent banding patterns and chromatic heterogeneity for the W chromosome

Caryologia, 2021
Chromosomal rearrangements are an important process in the evolution of species. It is assumed that these rearrangements occur near repetitive sequences and heterochromatic regions.
Alice Lemos Costa, Cassiane Furlan Lopes, Marcelo Santos de Souza, Suziane Alves Barcellos, Pâmela Giordani Vielmo, Ricardo José Gunski, Analía Del Valle Garnero   +6 more
doaj  

Karyotypic variation in the Andean rodent Phyllotis xanthopygus (Waterhouse, 1837) (Rodentia, Cricetidae, Sigmodontinae) [PDF]

, 2014
Phyllotis xanthopygus (Waterhouse, 1837) is an Andean rodent endemic to South America. Despite its wide geographical distribution in Argentina, few individuals have been studied on the cytogenetic level and only through conventional staining.
Cuello, Pablo Andrés, Labaroni, Carolina Alicia, Lanzone, Cecilia, Malleret, Matías Maximiliano, Marti, Dardo Andrea, Novillo, Agustina, Ojeda, Agustina Alejandra, Ojeda, Agustina Alejandra, Rodriguez, Daniela   +8 more
core   +4 more sources