Results 31 to 40 of about 76,927 (296)

Chromosome Rearrangements in Canine Fibrosarcomas [PDF]

Journal of Heredity, 2005
We have previously reported the use of six- and seven-color paint sets in the analysis of canine soft tissue sarcomas. Here we combine this technique with flow sorting of translocation chromosomes, reverse painting, and polymerase chain reaction (PCR) analysis of the gene content of the reverse paint in order to provide a more detailed analysis of ...
D R, Sargan, B S, Milne, J Aguirre, Hernandez, P C M, O'Brien, M A, Ferguson-Smith, T, Hoather, J M, Dobson   +6 more
openaire   +2 more sources

Karyotypic Evolution of the Common and Silverleaf Sunflower Genomes

The Plant Genome, 2009
Silverleaf sunflower ( Torrey and Gray) has been an important source of favorable alleles for broadening genetic diversity and enhancing agriculturally important traits in common sunflower ( L.), and, as the closest living relative of , provides an ...
Adam F. Heesacker, Eleni Bachlava, Robert L. Brunick, John M. Burke, Loren H. Rieseberg, Steven J. Knapp   +5 more
doaj   +1 more source

Chromothripsis is a common mechanism driving genomic rearrangements in primary and metastatic colorectal cancer [PDF]

, 2011
: BACKGROUND: Structural rearrangements form a major class of somatic variation in cancer genomes. Local chromosome shattering, termed chromothripsis, is a mechanism proposed to be the cause of clustered chromosomal rearrangements and was recently ...
Cuppen, E., Marlous Hoogstraat, Lieshout, S., van, Stef van Lieshout, Ivo Renkens, van Lieshout, S., Roosmalen van, M., Belt van de, J., Marco Koudijs, Hoogstraat, M., Voest, E.E., Koudijs, M.J., Isaac J Nijman, Edwin Cuppen, van Roosmalen, M., Ruben van 't Slot, José van de Belt, Masoumeh Tavakoli-Yaraki, Wijnand Roessingh, Vermaat, J.S., Slot, R., van 't, Nijman, I.J., Kloosterman, W.P., Lieshout van, S., Emile Voest, Renkens, I., Oscar Paling, Joost S Vermaat, Vermaat, J.E., Wigard P Kloosterman, Van't Slot, R., Belt, J., van de, van de Belt, J., Roessingh, W., Paling, O., Slot Van't, R., Guryev, V., Roosmalen, M.J., van, Tavakoli-Yaraki, M., Victor Guryev, Markus J van Roosmalen   +40 more
core   +2 more sources

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Stanyon, Roscoe, Cremer, Thomas, Wienberg, Johannes, Jauch, Anna   +3 more
core   +1 more source

Interstitial deletion 4p15.32p16.1 and complex chromoplexy in a female proband with severe neurodevelopmental delay, growth failure and dysmorphism

Molecular Cytogenetics, 2022
Complex chromosomal rearrangements involve the restructuring of genetic material within a single chromosome or across multiple chromosomes. These events can cause serious human disease by disrupting coding DNA and gene regulatory elements via deletions ...
Dong Li, Alanna Strong, Cuiping Hou, Helen Downes, Amanda Barone Pritchard, Pamela Mazzeo, Elaine H. Zackai, Laura K. Conlin, Hakon Hakonarson   +8 more
doaj   +1 more source

Case report: Optical genome mapping revealed double rearrangements in a male undergoing preimplantation genetic testing

Frontiers in Genetics, 2023
Chromosome rearrangement is one of the main causes of abortion. In individuals with double chromosomal rearrangements, the abortion rate and the risk of producing abnormal chromosomal embryos are increased.
Jun Ren, Jun Ren, Jun Ren, Yuezhi Keqie, Yuezhi Keqie, Yuezhi Keqie, Yutong Li, Yutong Li, Yutong Li, Lingping Li, Lingping Li, Lingping Li, Min Luo, Min Luo, Min Luo, Meng Gao, Meng Gao, Meng Gao, Cuiting Peng, Cuiting Peng, Cuiting Peng, Han Chen, Han Chen, Han Chen, Ting Hu, Ting Hu, Ting Hu, Xinlian Chen, Xinlian Chen, Xinlian Chen, Shanling Liu, Shanling Liu, Shanling Liu   +32 more
doaj   +1 more source

Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]

, 2000
At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Mittermueller, J., Gerhartz, Helmut Heinrich, Schmetzer, Helga Maria, Braun, S., Wiesner, D., Duell, T.   +5 more
core   +1 more source

Comparative studies of X chromosomes in Cervidae family

Scientific Reports, 2023
The family Cervidae is the second most diverse in the infraorder Pecora and is characterized by variability in the diploid chromosome numbers among species.
Anastasia A. Proskuryakova, Ekaterina S. Ivanova, Alexey I. Makunin, Denis M. Larkin, Malcolm A. Ferguson-Smith, Fengtang Yang, Olga V. Uphyrkina, Polina L. Perelman, Alexander S. Graphodatsky   +8 more
doaj   +1 more source

Chromosomal rearrangements and karyotype evolution in carnivores revealed by chromosome painting [PDF]

, 2011
Chromosomal evolution in carnivores has been revisited extensively using cross-species chromosome painting. Painting probes derived from flow-sorted chromosomes of the domestic dog, which has one of the most rearranged karyotypes in mammals and the ...
Perelman, P. L., Graphodatsky, A. S., Nie, W., W Su, Yang, F., A Tanomtong, P L Perelman, Su, W., Tanomtong, A., D Wang, J Wang, Wang, J., Nie, W (reprint author), Chinese Acad Sci, Kunming Inst Zool, State Key Lab Genet Resources & Evolut, Kunming 650223, Yunnan, Peoples R China, Wang, D., A S Graphodatsky, W Nie, F Yang   +16 more
core   +1 more source

Origin, Regulation, and Fitness Effect of Chromosomal Rearrangements in the Yeast Saccharomyces cerevisiae [PDF]

, 2021
Chromosomal rearrangements comprise unbalanced structural variations resulting in gain or loss of DNA copy numbers, as well as balanced events including translocation and inversion that are copy number neutral, both of which contribute to phenotypic ...
Xing-Xing Tang, Ying-Xuan Zhu, Xue-Ping Wen, Dao-Qiong Zheng, Lei Qi, Yang Sui   +5 more
core   +1 more source