Results 31 to 40 of about 1,002,198 (296)

Micronuclei-based model system reveals functional consequences of chromothripsis in human cells

eLife, 2019
Cancer cells often harbor chromosomes in abnormal numbers and with aberrant structure. The consequences of these chromosomal aberrations are difficult to study in cancer, and therefore several model systems have been developed in recent years.
Maja Kneissig, Kristina Keuper, Mirjam S de Pagter, Markus J van Roosmalen, Jana Martin, Hannah Otto, Verena Passerini, Aline Campos Sparr, Ivo Renkens, Fenna Kropveld, Anand Vasudevan, Jason M Sheltzer, Wigard P Kloosterman, Zuzana Storchova   +13 more
doaj   +1 more source

Chromosomal control of pig populations in France: 2002-2006 survey [PDF]

, 2007
The chromosomal control of pig populations has been widely developed in France over the last ten years. By December 31st, 2006, 13 765 individuals had been karyotyped in our laboratory, 62% of these since 2002.
BERLAND, H.M., Alain Pinton, Mary, Nicolas, Darré, Roland, Nicolas Mary, Alain Ducos, Roland Darré, Amélie Garnier-Bonnet, Hélène-Marie Berland, BILLOUX, S., Garnier-Bonnet, Amélie, BONNET, N., Ducos, Alain, Berland, Hélène-Marie, Bonnet, Nathalie, Anne Calgaro, Pinton, Alain, Billoux, Sébastien, Calgaro, Anne, Nathalie Bonnet, Sébastien Billoux, GARNIER-BONNET, A.   +21 more
core   +1 more source

Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution [PDF]

, 2010
Chromosomal rearrangements and copy number variants (CNVs) play key roles in genome evolution and genetic disease; however, the molecular mechanisms underlying these types of structural genomic variation are not fully understood.
Skinner, Benjamin M., Bunzey, Sydney K., Ellegren, Hans, Völker, Martin, Backström, Niclas, Langley, Elizabeth J, Griffin, Darren K.   +6 more
core   +1 more source

Chromosomal rearrangements formed by rrn recombination do not improve replichore balance in host-specific Salmonella enterica serovars. [PDF]

PLoS ONE, 2010
Most of the ∼2,600 serovars of Salmonella enterica have a broad host range as well as a conserved gene order. In contrast, some Salmonella serovars are host-specific and frequently exhibit large chromosomal rearrangements from recombination between rrn ...
T David Matthews, Robert Edwards, Stanley Maloy   +2 more
doaj   +1 more source

Preimplantation Genetic Testing for Chromosomal Abnormalities: Aneuploidy, Mosaicism, and Structural Rearrangements

Genes, 2020
There is a high incidence of chromosomal abnormalities in early human embryos, whether they are generated by natural conception or by assisted reproductive technologies (ART).
M. Viotti
semanticscholar   +1 more source

The origin of human chromosome 2 analyzed by comparative chromosome mapping with a DNA microlibrary [PDF]

, 1994
Fluorescencein situ hybridization (FISH) of microlibraries established from distinct chromosome subregions can test the evolutionary conservation of chromosome bands as well as chromosomal rearrangements that occurred during primate evolution and will ...
Cremer, Thomas, Senger, G., Wienberg, Johannes, Claussen, U., Horsthemke, B., Arnold, N., Lüdecke, H. J., Jauch, Anna, Lengauer, Christoph   +8 more
core   +1 more source

Chromosome Rearrangements in Canine Fibrosarcomas [PDF]

Journal of Heredity, 2005
We have previously reported the use of six- and seven-color paint sets in the analysis of canine soft tissue sarcomas. Here we combine this technique with flow sorting of translocation chromosomes, reverse painting, and polymerase chain reaction (PCR) analysis of the gene content of the reverse paint in order to provide a more detailed analysis of ...
D R, Sargan, B S, Milne, J Aguirre, Hernandez, P C M, O'Brien, M A, Ferguson-Smith, T, Hoather, J M, Dobson   +6 more
openaire   +2 more sources

Replication timing and epigenome remodelling are associated with the nature of chromosomal rearrangements in cancer

Nature Communications, 2019
DNA replication timing is known to facilitate the establishment of the epigenome, however, the intimate connection between replication timing and changes to the genome and epigenome in cancer remain largely uncharacterised. Here, we perform Repli-Seq and
Q. Du, Saul A. Bert, Nicola J. Armstrong, C. Caldon, Jenny Song, Shalima Nair, Cathryn M. Gould, Phuc-Loi Luu, Timothy J. Peters, Amanda Khoury, Wenjia Qu, E. Zotenko, C. Stirzaker, Sue J Clark   +13 more
semanticscholar   +1 more source

Karyotypic Evolution of the Common and Silverleaf Sunflower Genomes

The Plant Genome, 2009
Silverleaf sunflower ( Torrey and Gray) has been an important source of favorable alleles for broadening genetic diversity and enhancing agriculturally important traits in common sunflower ( L.), and, as the closest living relative of , provides an ...
Adam F. Heesacker, Eleni Bachlava, Robert L. Brunick, John M. Burke, Loren H. Rieseberg, Steven J. Knapp   +5 more
doaj   +1 more source

Case report: Optical genome mapping revealed double rearrangements in a male undergoing preimplantation genetic testing

Frontiers in Genetics, 2023
Chromosome rearrangement is one of the main causes of abortion. In individuals with double chromosomal rearrangements, the abortion rate and the risk of producing abnormal chromosomal embryos are increased.
Jun Ren, Jun Ren, Jun Ren, Yuezhi Keqie, Yuezhi Keqie, Yuezhi Keqie, Yutong Li, Yutong Li, Yutong Li, Lingping Li, Lingping Li, Lingping Li, Min Luo, Min Luo, Min Luo, Meng Gao, Meng Gao, Meng Gao, Cuiting Peng, Cuiting Peng, Cuiting Peng, Han Chen, Han Chen, Han Chen, Ting Hu, Ting Hu, Ting Hu, Xinlian Chen, Xinlian Chen, Xinlian Chen, Shanling Liu, Shanling Liu, Shanling Liu   +32 more
doaj   +1 more source