Results 11 to 20 of about 1,002,198 (296)
Sequence features contributing to chromosomal rearrangements in Neisseria gonorrhoeae. [PDF]
PLoS ONE, 2012 Through whole genome sequence alignments, breakpoints in chromosomal synteny can be identified and the sequence features associated with these determined.
Russell Spencer-Smith +3 more
doaj +2 more sources
Investigating Potential Chromosomal Rearrangements during Laboratory Culture of Neisseria gonorrhoeae [PDF]
Microorganisms, 2018 Comparisons of genome sequence data between different strains and isolates of Neisseria spp., such as Neisseria gonorrhoeae, reveal that over the evolutionary history of these organisms, large scale chromosomal rearrangements have occurred.
Russell Spencer-Smith +3 more
doaj +2 more sources
Identification of complex and cryptic chromosomal rearrangements by optical genome mapping
Molecular Cytogenetics, 2023 Background Optical genome mapping (OGM) has developed into a highly promising method for detecting structural variants (SVs) in human genomes. Complex chromosomal rearrangements (CCRs) and cryptic translocations are rare events that are considered ...
Shanshan Shi +3 more
doaj +2 more sources
Cytogenetic techniques in current biomedical research. Part II: chromosomal rearrangements
Фундаментальная и клиническая медицина, 2022 Mutations represent a natural mechanism for adaptation of species to changing environmental conditions. Chromosomal rearrangements play a pivotal role in the evolution, as evidenced by the comparison of human and non-human primate karyotypes, and have ...
А. N. Volkov, O. I. Rytenkova
doaj +2 more sources
On the spot: very local chromosomal rearrangements [PDF]
F1000 Biology Reports, 2012 Over the last decade, the detection of chromosomal abnormalities has shifted from conventional karyotyping under a light microscope to molecular detection using microarrays. The latter technology identified copy number variation as a major source of variation in the human genome; moreover, copy number variants were found responsible for 10-20% of cases
Helsmoortel, Céline +2 more
openaire +4 more sources
The Impact of Chromosomal Rearrangements in Speciation: From Micro- to Macroevolution.
Cold Spring Harbor Perspectives in Biology, 2023 Chromosomal rearrangements (CRs) have been known since almost the beginning of genetics. While an important role for CRs in speciation has been suggested, evidence primarily stems from theoretical and empirical studies focusing on the microevolutionary ...
Kay Lucek +7 more
semanticscholar +1 more source
Engineering chromosome rearrangements in cancer [PDF]
Disease Models & Mechanisms, 2021 ABSTRACT The identification of large chromosomal rearrangements in cancers has multiplied exponentially over the last decade. These complex and often rare genomic events have traditionally been challenging to study, in part owing to lack of tools that efficiently engineer disease-associated inversions, deletions and translocations in ...
Salvador Alonso, Lukas E. Dow
openaire +3 more sources
Frontiers in Plant Science, 2021 Tandem repeats can occupy a large portion of plant genomes and can either cause or result from chromosomal rearrangements, which are important drivers of dysploidy-mediated karyotype evolution and speciation.
N. Waminal +3 more
semanticscholar +1 more source
Identification of a familial complex chromosomal rearrangement by optical genome mapping
Molecular Cytogenetics, 2022 Background Complex chromosomal rearrangements (CCRs) are rare chromosomal structural variations, containing a variety of rearrangements such as translocation, inversion and/or insertion.
Yang Yang, Wang Hao
doaj +1 more source
PLoS Genetics, 2021 Different species can find convergent solutions to adapt their genome to the same evolutionary constraints, although functional convergence promoted by chromosomal rearrangements in different species has not previously been found.
Laura G Macías +7 more
doaj +1 more source