Results 21 to 30 of about 267,700 (194)

Copy number variation, chromosome rearrangement, and their association with recombination during avian evolution [PDF]

, 2010
Chromosomal rearrangements and copy number variants (CNVs) play key roles in genome evolution and genetic disease; however, the molecular mechanisms underlying these types of structural genomic variation are not fully understood.
Skinner, Benjamin M., Bunzey, Sydney K., Ellegren, Hans, Völker, Martin, Backström, Niclas, Langley, Elizabeth J, Griffin, Darren K., Skinner, Benjamin M, Bunzey, Sydney K, Griffin, Darren K, Ellegren, Hans,, Backström, Niclas,   +11 more
core   +1 more source

Chromosomal Rearrangements and Transposable Elements in Locally Adapted Island Drosophila. [PDF]

Genome Biol Evol
Chromosomal rearrangements, particularly those mediated by transposable elements (TEs), can drive adaptive evolution by creating chimeric genes, inducing de novo gene formation, or altering gene expression.
Turner BA, Erlenbach TR, Stewart NB, Reid RW, Moore CC, Rogers RL.   +5 more
europepmc   +3 more sources

Micronuclei-based model system reveals functional consequences of chromothripsis in human cells

eLife, 2019
Cancer cells often harbor chromosomes in abnormal numbers and with aberrant structure. The consequences of these chromosomal aberrations are difficult to study in cancer, and therefore several model systems have been developed in recent years.
Maja Kneissig, Kristina Keuper, Mirjam S de Pagter, Markus J van Roosmalen, Jana Martin, Hannah Otto, Verena Passerini, Aline Campos Sparr, Ivo Renkens, Fenna Kropveld, Anand Vasudevan, Jason M Sheltzer, Wigard P Kloosterman, Zuzana Storchova   +13 more
doaj   +1 more source

Chromosomal Rearrangements and Chromothripsis: The Alternative End Generation Model. [PDF]

Int J Mol Sci, 2023
Chromothripsis defines a genetic phenomenon where up to hundreds of clustered chromosomal rearrangements can arise in a single catastrophic event. The phenomenon is associated with cancer and congenital diseases.
de Groot D, Spanjaard A, Hogenbirk MA, Jacobs H.   +3 more
europepmc   +2 more sources

Seven-fluorochrome mouse M-FISH for high-resolution analysis of interchromosomal rearrangements [PDF]

, 2003
The mouse has evolved to be the primary mammalian genetic model organism. Important applications include the modeling of human cancer and cloning experiments. In both settings, a detailed analysis of the mouse genome is essential.
Geigl, J., Speicher, M. R., Klein, C. A., Klein, C.A., Jentsch, I., Speicher, M.R., Jentsch, I;Geigl, J;Klein, CA;Speicher, MR, Jentsch, I.;Geigl, J.;Klein, C. A.;Speicher, M. R.   +7 more
core   +1 more source

Chromosomal control of pig populations in France: 2002-2006 survey [PDF]

, 2007
The chromosomal control of pig populations has been widely developed in France over the last ten years. By December 31st, 2006, 13 765 individuals had been karyotyped in our laboratory, 62% of these since 2002.
BERLAND, H.M., Alain Pinton, Mary, Nicolas, Darré, Roland, Nicolas Mary, Alain Ducos, Roland Darré, Amélie Garnier-Bonnet, Hélène-Marie Berland, BILLOUX, S., Garnier-Bonnet, Amélie, BONNET, N., Ducos, Alain, Berland, Hélène-Marie, Bonnet, Nathalie, Anne Calgaro, Pinton, Alain, Billoux, Sébastien, Calgaro, Anne, Nathalie Bonnet, Sébastien Billoux, GARNIER-BONNET, A.   +21 more
core   +2 more sources

Chromosomal rearrangements formed by rrn recombination do not improve replichore balance in host-specific Salmonella enterica serovars. [PDF]

PLoS ONE, 2010
Most of the ∼2,600 serovars of Salmonella enterica have a broad host range as well as a conserved gene order. In contrast, some Salmonella serovars are host-specific and frequently exhibit large chromosomal rearrangements from recombination between rrn ...
T David Matthews, Robert Edwards, Stanley Maloy   +2 more
doaj   +1 more source

Sequence features contributing to chromosomal rearrangements in Neisseria gonorrhoeae. [PDF]

PLoS ONE, 2012
Through whole genome sequence alignments, breakpoints in chromosomal synteny can be identified and the sequence features associated with these determined.
Russell Spencer-Smith, Eldho M Varkey, Mark D Fielder, Lori A S Snyder   +3 more
doaj   +1 more source

Chromosome Rearrangements in Canine Fibrosarcomas [PDF]

Journal of Heredity, 2005
We have previously reported the use of six- and seven-color paint sets in the analysis of canine soft tissue sarcomas. Here we combine this technique with flow sorting of translocation chromosomes, reverse painting, and polymerase chain reaction (PCR) analysis of the gene content of the reverse paint in order to provide a more detailed analysis of ...
D R, Sargan, B S, Milne, J Aguirre, Hernandez, P C M, O'Brien, M A, Ferguson-Smith, T, Hoather, J M, Dobson   +6 more
openaire   +2 more sources

Molecular cytotaxonomy of primates by chromosomal in situ suppression hybridization [PDF]

, 1990
A new strategy for analyzing chromosomal evolution in primates is presented using chromosomal in situ suppression (CISS) hybridization. Biotin-labeled DNA libraries from flow-sorted human chromosomes are hybridized to chromosome preparations of ...
Stanyon, Roscoe, Cremer, Thomas, Wienberg, Johannes, Jauch, Anna   +3 more
core   +1 more source