Results 51 to 60 of about 131,087 (254)

Chromosome Rearrangements in Canine Fibrosarcomas [PDF]

Journal of Heredity, 2005
We have previously reported the use of six- and seven-color paint sets in the analysis of canine soft tissue sarcomas. Here we combine this technique with flow sorting of translocation chromosomes, reverse painting, and polymerase chain reaction (PCR) analysis of the gene content of the reverse paint in order to provide a more detailed analysis of ...
D R, Sargan, B S, Milne, J Aguirre, Hernandez, P C M, O'Brien, M A, Ferguson-Smith, T, Hoather, J M, Dobson   +6 more
openaire   +2 more sources

High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing.

PLoS ONE, 2018
The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis-a low-resolution genome-wide chromosome analysis-is still the gold standard, it often needs to be complemented with ...
Anh Nhi Tran, Fulya Taylan, Vasilios Zachariadis, Ingegerd Ivanov Öfverholm, Anna Lindstrand, Francesco Vezzi, Britta Lötstedt, Magnus Nordenskjöld, Ann Nordgren, Daniel Nilsson, Gisela Barbany   +10 more
doaj   +1 more source

Investigating Potential Chromosomal Rearrangements during Laboratory Culture of Neisseria gonorrhoeae

Microorganisms, 2018
Comparisons of genome sequence data between different strains and isolates of Neisseria spp., such as Neisseria gonorrhoeae, reveal that over the evolutionary history of these organisms, large scale chromosomal rearrangements have occurred.
Russell Spencer-Smith, Simon W. Gould, Madhuri Pulijala, Lori A. S. Snyder   +3 more
doaj   +1 more source

Fusion Genes and RNAs in Cancer Development

Non-Coding RNA, 2021
Fusion RNAs are a hallmark of some cancers. They result either from chromosomal rearrangements or from splicing mechanisms that are non-chromosomal rearrangements.
Kenzui Taniue, Nobuyoshi Akimitsu
doaj   +1 more source

A Preliminary Investigation on the Chromosome Aberrations in Acute Lymphoblastic Leukaemia Using Multiprobe Fluorescence In Situ Hybridization Panel

Bezmiâlem Science, 2022
Objective:Acute lymphoblastic leukemia (ALL) is a disease related to the overproduction of immature lymphocytes. For diagnosis and classification of ALL, recognizing chromosome aberrations using conventional cytogenetic analysis (CCA) is essential ...
Bengisu GÖKKAYA, Sezen ATASOY, Ayşe ÇIRAKOĞLU, Yelda TARKAN ARGÜDEN, R. Dilhan KURU, Şükriye YILMAZ, Şeniz ÖNGÖREN, Ayhan DEVİREN   +7 more
doaj   +1 more source

Chromosomal rearrangements in chondromatous tumors [PDF]

Cancer, 1990
Short-term cultures from 16 chondromatous tumors, 15 primary and one recurrent, were analyzed cytogenetically. Clonal chromosome aberrations were found in one of six benign tumors and in seven of ten malignant tumors. A chondroma had a complex translocation involving chromosomes X, 8, 12, and 13, as well as a deletion of the derivative chromosome 8. In
N, Mandahl, S, Heim, K, Arheden, A, Rydholm, H, Willén, F, Mitelman   +5 more
openaire   +2 more sources

Genome reorganization in different cancer types: detection of cancer specific breakpoint regions [PDF]

, 2019
Background: Tumorigenesis is a multi-step process which is accompanied by substantial changes in genome organization. The development of these changes is not only a random process, but rather comprise specific DNA regions that are prone to the ...
Klein, Andreas, Parczyk, Jonas, Ruhnau, Jerome, Standfuß, Christoph   +3 more
core   +1 more source

A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers. [PDF]

, 2016
Gross chromosomal rearrangements (GCRs) play an important role in human diseases, including cancer. The identity of all Genome Instability Suppressing (GIS) genes is not currently known.
Bell, Sara N, Clotfelter, Sarah P, de Souza, Jorge ES, de Souza, Sandro J, Fonseca, André F, Kolodner, Richard D, Martinez, Sandra L, Nene, Rahul V, Putnam, Christopher D, Somach, Steven B, Srivatsan, Anjana   +10 more
core   +2 more sources

High-Definition Cytogenetic Mapping of modern sugarcane cultivars by Oligo-FISH

Industrial Crops and Products
Sugarcane (Saccharum spp.), a dual-purpose crop valued for sugar and energy production, serves as an important industrial raw material and has substantial economic impact.
Qilong Ling, Junpeng Yang, Yu Tang, Xiaoying Huang, Wei Yao, Zuhu Deng, Muqing Zhang, Fan Yu   +7 more
doaj   +1 more source

The molecular basis of T cell acute lymphoblastic leukemia [PDF]

, 2012
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando, Bash, Bash, Chen, Condorelli, Dube, Fisch, Hagemeijer, Hebert, Ho, Kelliher, Kikuchi, Larson, Lu, McGuire, McGuire, Nagel, Ntziachristos, Ntziachristos, Ono, Pieter Van Vlierberghe, Royer-Pokora, Rubnitz, van Grotel   +23 more
core   +1 more source