Results 171 to 180 of about 85,626 (243)

Chromosome Translocations in the Common Wheat Variety ‘Amigo’ [PDF]

, 2004
Xiwen Cai
openalex   +1 more source

Analysis of sperm chromosomes in six carriers of rare and common Robertsonian translocations^*

, 2021
Marta Olszewska, Ewa Wiland, Elżbieta Wanowska, Nataliya Huleyuk, В. Б. Черных, D. V. Zastavna, Maciej Kurpisz   +6 more
openalex   +1 more source

LRRK2 as a Potential Disease‐Modifying Target in Sporadic Parkinson's Disease

Movement Disorders, EarlyView.
Abstract A growing understanding of the role that leucine‐rich repeat kinase 2 (LRRK2) plays in Parkinson's disease (PD) supports continued focus on this enzyme as a therapeutic target for PD. Accumulating evidence suggests that there are phenotypic, neuropathologic, and biological similarities between sporadic PD (sPD) and familial forms in which ...
Anthony E. Lang, Robert A. Hauser, Lorraine V. Kalia, Bonnie Hersh, Zdenek Berger, Roy Llorens Arenas, Coro Paisan‐Ruiz, Kyle Fraser, Danna Jennings, Jillian H. Kluss, Sarah Huntwork‐Rodriguez, Anastasia G. Henry, J. Timothy Greenamyre   +12 more
wiley   +1 more source

Identification of allelic relationship and translocation region among chromosomal translocation lines that leads to less-seed watermelon. [PDF]

Hortic Res
Jiao D, Zhao H, Sun H, Zhang J, Zhang H, Gong G, Anees M, Zhu H, Liu W, Xu Y.   +9 more
europepmc   +1 more source

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, EarlyView.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Age and Serum AMH and FSH Levels as Predictors of the Number of Oocytes Retrieved from Chromosomal Translocation Carriers after Controlled Ovarian Hyperstimulation: Applicability and Limitations. [PDF]

Genes (Basel), 2020
Shilenkova YV, Pendina AA, Mekina ID, Efimova OA, Komarova EM, Lesik EA, Ishchuk MA, Fedorova EM, Chiryaeva OG, Petrova LI, Dudkina VS, Talantova OE, Gzgzyan AM, Kogan IY.   +13 more
europepmc   +1 more source

TRANSLOCATIONS IN MAIZE INVOLVING THE SHORT ARM OF CHROMOSOME I [PDF]

, 1941
Edgar Anderson
openalex   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Uncovering the Genetic Landscape of Spinal Dysraphism: A Retrospective Analysis of 150 Fetal Cases

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Spinal dysraphism (SD) results from incomplete neural tube closure and encompasses a heterogeneous group of congenital anomalies with genetic and environmental etiologies. Although genetic contributions are recognized, causative variants remain insufficiently defined, and the clinical implications of extended genetic testing on ...
I. Bedei, A. Feresin, R. Zemet, D. Berner, D. Polidori, K. Fröbius, A. Skakkebæk, R. Axt‐Fliedner, M. Shoukier, C. Keil   +9 more
wiley   +1 more source

CRISPR Gene Editing of Murine Blood Stem and Progenitor Cells Induces MLL-AF9 Chromosomal Translocation and MLL-AF9 Leukaemogenesis. [PDF]

Int J Mol Sci, 2020
Sarrou E, Richmond L, Carmody RJ, Gibson B, Keeshan K.   +4 more
europepmc   +1 more source