Results 191 to 200 of about 1,000,004 (376)

An Additional Report of a Female With a Complex XY Translocation Is Presented Who Has Successfully Completed a Pregnancy With Significant Y Chromosome Material Gain and Partial X Deletion

American Journal of Medical Genetics Part A, EarlyView.
John Coleman, Nicola Walsh, Deborah M. Lambert, Andrew Green, Sally Ann Lynch   +4 more
wiley   +1 more source

Comparative Analysis of HEK293 Genomic Variability

Biotechnology and Bioengineering, EarlyView.
An investigation of how HEK293‐derived cell lines adapt genetically to different culture conditions and environmental pressures: despite distinct phenotypes and cultivation histories, comparative whole‐genome analyses of established HEK293 variants as well as newly suspension‐adapted cells revealed a shared, common set of mutations linked to cell ...
Georg Smesnik, Nikolaus Virgolini, Maria Toth, Astrid Dürauer, Nicole Borth   +4 more
wiley   +1 more source

Delivery strategies of messenger RNA therapeutics for brain disorders

Bulletin of the Korean Chemical Society, EarlyView.
Thus, mRNA therapeutics offer a powerful new avenue for the treatment of brain diseases. This review examines strategies to bypass biological barriers, particularly the blood–brain barrier, and explores emerging delivery systems, such as direct intracerebral injection, intracerebroventricular injection, systemic delivery (including intravenous ...
Kounghwa Youn, Sunmin Oh, Hyunchae Gil, Yongseok Choi, Gyochang Keum, Eun‐Kyoung Bang   +5 more
wiley   +1 more source

Chromosome Translocation t(14;21)(q11;q22) Activates Both OLIG1 and OLIG2 in Pediatric T-cell Lymphoblastic Malignancies and May Signify Adverse Prognosis [PDF]

, 2019
Ioannis Panagopoulos, Ludmila Gorunova, Inga María Jóhannsdóttir, Kristin Andersen, Arild Holth, Klaus Beiske, Sverre Heim   +6 more
openalex   +1 more source

Multi‐Omics‐Driven Adaptive Management of Biological Invasions: Toward a Proactive, Predictive, and Integrative Framework

Biological Diversity, EarlyView.
A proactive, predictive, and integrative framework that integrates multi‐omics innovations with ecological modeling and big data analytics to guide adaptive interventions and governance in invasive species management. By integrating multi‐omics insights with advanced ecological modeling, remote sensing, artificial intelligence, and cross‐disciplinary ...
Aibin Zhan
wiley   +1 more source

Paintig of defined chromosomal regions by in situ suppression hybridization of libraries from laser-microdissected chromosomes [PDF]

, 1991
Cremer, Thomas, Eckelt, A., Endlich, N., Greulich, K. O., Lengauer, Christoph, Lichter, Peter, Ponelies, N., Weith, A.   +7 more
core   +1 more source

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

Journal of Clinical Investigation, 2012
L. Chu, Mack Y Su, Leonard Maggi, Lan Lu, C. Mullins, S. Crosby, Gaofeng Huang, W. Chng, R. Vij, M. Tomasson   +9 more
semanticscholar   +1 more source

Molecular cytogenetics analysis with whole chromosome paint probes of sperm nuclei from a (13;15) Robertsonian translocation carrier [PDF]

, 2005
Nathalie Rives, Célia Ravel, Véronique Duchesne, Jean‐Pierre Siffroi, Nathalie Mousset‐Siméon, Bertrand Macé   +5 more
openalex   +1 more source

Advances in Pharmacological Insights of Borago officinalis: A Comprehensive Review

Biological Diversity, EarlyView.
ABSTRACT Recent growth in phytotherapy and product‐based drug development has increased interest in this plant because of its broad pharmacological activity. This review aims to examine the pharmacological activities, mechanisms, and potential applications of Borago officinalis, focusing on its primary bioactive constituents and therapeutic ...
Zahra Sufwan, Javed Akhtar Ansari, Farogh Ahsan   +2 more
wiley   +1 more source

Chromosomal translocation t(11;14) and p53 deletion induced by the CRISPR/Cas9 system in normal B cell-derived iPS cells. [PDF]

Sci Rep, 2021
Azami Y, Tsuyama N, Abe Y, Sugai-Takahashi M, Kudo KI, Ota A, Sivasundaram K, Muramatsu M, Shigemura T, Sasatani M, Hashimoto Y, Saji S, Kamiya K, Hanamura I, Ikezoe T, Onodera M, Sakai A.   +16 more
europepmc   +1 more source