Results 191 to 200 of about 986,967 (334)

A mentally retarded child with a translocation involving chromosomes 12 and 19. [PDF]

, 1975
T W Histinx, F.J.M. Gabreëls, F. J. Rutten, I I Korten, J. M. J. C. Scheres, E.M.G. Joosten   +5 more
openalex   +1 more source

Decreased RYR2 Cluster Size and Abnormal SR Ca2+ Release Contribute to Arrhythmogenesis in TMEM43‐Related ARVC

Advanced Science, EarlyView.
The TMEM43 ‐ P386S mutation causes arrhythmogenic right ventricular cardiomyopathy (ARVC) by mislocalizing itself from nuclear envelope (NE) to cytoplasm, disrupting lamin B2 (a novel TMEM43 interactor) localization, NE integrity and chromatin accessibility, causing hyper ‐ phosphorylation and reduced expression/clustering of ryanodine receptor type 2 (
Jiaxi Shen, Xiaochen Wang, Hangping Fan, Yaxun Sun, Tingyu Gong, Hangyuan Qiu, Jue Wang, Ziwei Pan, Yanna Dang, Hongkun Wang, Danni Zhou, Tianyi Zhu, Hao Wang, Xianzhen Chen, Lizhen Xu, Jun Su, Fan Yang, Yiquan Tang, Xuguang Li, Bing Yang, Lenan Zhuang, Wei Wang, Chenyang Jiang, Ping Liang   +23 more
wiley   +1 more source

The Association of D-Group Chromosomal Translocations and Defective Spermatogenesis [PDF]

, 1976
Stephen R. Plymate, William J. Bremner, C. Alvin Paulsen   +2 more
openalex   +1 more source

Harnessing the Biological Responses Induced by Nanomaterials for Enhanced Cancer Therapy

Aggregate, EarlyView.
Nanomaterial (NM)‐induced toxicity can be strategically repurposed for cancer therapy. This review summarizes the mechanism by which NMs selectively activate specific cellular processes to regulate cell fate independently. We also discussed how NMs‐induced biological responses can be leveraged as therapeutic strategies for cancer treatment.
Liting Wang, Hao Fu, Jiangtao Lin, Meng Zhao, Chuanrong Chen, Hongze Liao, Yourong Duan   +6 more
wiley   +1 more source

Translocation of chromosome 4 and 9 with ring formation of chromosome 4 short arm. [PDF]

, 1978
Rinat Bernstein‐Molho, A T Milne, T Jenkins   +2 more
openalex   +1 more source

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

Cell, 1991
A. Kakizuka, W. Miller, K. Umesono, K. Umesono, R. Warrell, S. Frankel, V. Murty, E. Dmitrovsky, R. M. Evans, R. Evans   +9 more
semanticscholar   +1 more source

Large chromosomal structural variations between M. acuminata and M balbisiana and their consequences on chromosome recombination and segregation in a AAAB polyploidy context [PDF]

, 2017
Many banana cultivars are triploid interspecific hybrids between M. acuminata (Genome A, 2n=22) and M. balbisiana (Genome B, 2n=22). They included the important group of Plantain cooking bananas classified as AAB.
Baurens, Franc-Christophe, D'Hont, Angélique, Habas, Rémy, Martin, Guillaume, Njembele, J. Célestin, Ricci, Sébastien, Rouard, Mathieu, Salmon, Frédéric   +7 more
core  

Illuminating Tau Aggregates: Multiscale Approaches for Detection, Imaging, and Understanding

Aggregate, EarlyView.
This review presents recent advances in molecular imaging of tauopathies, focusing on tau aggregation mechanisms, structural polymorphism, and imaging strategies. It highlights the development of tau‐selective fluorescent probes and PET tracers and explores emerging techniques such as cryo‐EM and super‐resolution imaging, offering a multiscale ...
Kaustubh R. Bhuskute, Jiayi Fan, Amandeep Kaur   +2 more
wiley   +1 more source

QUINACRINE FLUORESCENT CHROMOSOME ANALYSIS OF THE SNELL TRANSLOCATION IN THE MOUSE [PDF]

, 1972
D.A. Miller, P. W. Allderdice, Richard E. Kouri, V.G. Dev, M. S. Grewal, O. J. Miller, John J. Hutton   +6 more
openalex   +1 more source

Speech and Language Disorders Associated With 7q31 Deletions Implicating FOXP2

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Some 7q31 deletions encompass FOXP2, a gene long associated with speech and language disorders. Intragenic pathogenic FOXP2 variants cause FOXP2‐related speech and language disorder, which has been well characterized in the literature. Conversely, the phenotype associated with 7q31 deletions is neglected.
Lottie D. Morison, Ruth Braden, David J. Amor, Angela T. Morgan   +3 more
wiley   +1 more source