Results 231 to 240 of about 1,000,004 (376)

The RNA tether model for human chromosomal translocation fragile zones. [PDF]

Trends Biochem Sci
Liu D, Hsieh CL, Lieber MR.
europepmc   +1 more source

The hidden regulators: Non‐coding RNAs in KMT2A‐rearranged acute lymphoblastic leukemia

International Journal of Cancer, EarlyView.
Abstract Acute lymphoblastic leukemia (ALL) driven by KMT2A rearrangements (KMT2A‐r) is an aggressive hematologic malignancy with poor prognosis and a high incidence in infants. While KMT2A fusion proteins drive leukemogenesis through transcriptional dysregulation, recent discoveries have highlighted the pivotal role of non‐coding RNAs (ncRNAs) in ...
Maria Augusta Poersch, Ana Carolina Rodrigues, Priscila Elias Ferreira Stricker, Alexandre Luiz Korte Azevedo, Daniel Pacheco Bruschi, Jaqueline Carvalho de Oliveira   +5 more
wiley   +1 more source

The chromosomal translocation t(1;6)(p35.3;p25.2), recurrent in chronic lymphocytic leukaemia, leads to RCC1::IRF4 fusion. [PDF]

Br J Haematol
Jayne S, López C, Put N, Nagel I, Lierman E, Penas EMM, Michaux L, Ahearne MJ, Walter HS, Bens S, Drewes C, Szczepanowski M, Schlesner M, Rosenstiel P, Wlodarska I, Siebert R, Dyer MJS.   +16 more
europepmc   +1 more source

Chromosomal translocations cause deregulated BCL6 expression by promoter substitution in B cell lymphoma. [PDF]

, 1995
B. H. Ye, Subba Rao Chaganti, Chia‐Che Chang, Huifeng Niu, Paolo Corradini, R.S.K. Chaganti, Riccardo Dalla‐Favera   +6 more
openalex   +1 more source

Soil‐borne legacy facilitates the dissemination of antibiotic resistance genes in soil–plant continua

iMeta, EarlyView.
Antimicrobial resistance (AMR) disseminates throughout the soil–plant continuum via complex microbial interactions. Plants shape root‐ and leaf‐associated microbiomes that sustain plant health; however, soil‐borne legacies—enriched with antibiotic‐producing microbes and resistance genes—govern AMR dynamics across agroecosystems.
Zufei Xiao, Kai Ding, Xiaodong Guo, Yi Zhao, Xinyuan Li, Daoyuan Jiang, Dong Zhu, Qinglin Chen, Mui‐Choo Jong, David W. Graham, Gang Li, Yong‐Guan Zhu   +11 more
wiley   +1 more source

Fusion of the COL4A5 Gene With NR2F2-AS1 in a Hemangioma Carrying a t(X;15)(q22;q26) Chromosomal Translocation. [PDF]

Cancer Genomics Proteomics, 2020
Panagopoulos I, Gorunova L, Lobmaier I, Andersen K, Lund-Iversen M, Micci F, Heim S.   +6 more
europepmc   +1 more source

Translocation-Capture Sequencing Reveals the Extent and Nature of Chromosomal Rearrangements in B Lymphocytes

Cell, 2011
Isaac A. Klein, W. Resch, M. Jankovic, Thiago Y. Oliveira, Arito Yamane, H. Nakahashi, M. D. Virgilio, Anne Bothmer, A. Nussenzweig, D. Robbiani, R. Casellas, M. Nussenzweig   +11 more
semanticscholar   +1 more source

Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model [PDF]

, 2015
Miwa Tanaka, Shuichi Yamaguchi, Yukari Yamazaki, Hideyuki Kinoshita, Koichiro Kuwahara, Kazuwa Nakao, Patrick Y. Jay, Tetsuo Noda, Takuro Nakamura   +8 more
openalex   +1 more source

False Positive or False Negative—An Interesting Case in Prenatal Diagnostic Laboratory

Journal of Clinical Laboratory Analysis, EarlyView.
A prenatal case in which discordant results were identified among SNP‐Array, PNBoBs, conventional karyotyping, and FISH, highlighting the importance of recognizing the limitations of various testing techniques for clinicians to avoid misdiagnosis and missed diagnosis.
Pingping Zhang, Yanmei Sun, Haishen Tian, Xuedong Shi, Limin Rong, Yali Li   +5 more
wiley   +1 more source

Identification of allelic relationship and translocation region among chromosomal translocation lines that leads to less-seed watermelon. [PDF]

Hortic Res
Jiao D, Zhao H, Sun H, Zhang J, Zhang H, Gong G, Anees M, Zhu H, Liu W, Xu Y.   +9 more
europepmc   +1 more source