Results 21 to 30 of about 864,921 (260)
Scaling Laws for Mitotic Chromosomes
Frontiers in Cell and Developmental Biology, 2021 During mitosis in higher eukaryotes, each chromosome condenses into a pair of rod-shaped chromatids. This process is co-regulated by the activity of several gene families, and the underlying biophysics remains poorly understood.
Eric M. Kramer +2 more
doaj +1 more source
GRAS-1 is a novel regulator of early meiotic chromosome dynamics in C. elegans.
PLoS Genetics, 2023 Chromosome movements and licensing of synapsis must be tightly regulated during early meiosis to ensure accurate chromosome segregation and avoid aneuploidy, although how these steps are coordinated is not fully understood.
Marina Martinez-Garcia +16 more
doaj +1 more source
Chromosome 1 abnormalities in cervical carcinoma [PDF]
Cancer, 1988 Abnormalities of chromosome 1 have been reported in a number of solid tumors and hematologic malignancies, indicating that this is a frequent event in neoplasia. Here we report our observations on aberrations of chromosome 1 in malignancies of the uterine cervix.
Sreekantaiah, C. +2 more
openaire +2 more sources
Mapping Creb-1 to chromosome 1 in the mouse
Genomics, 1992 The gene CREB1 encoding the cyclic AMP response element DNA binding protein was previously assigned to human 2q32.3-q34. In this study, a panel of 207 backcross mice made between C57BL/10ScSn (=B10) females and (B10 x B10.L-Lsh)F1 males were used to map Creb-1 with respect to Cryg and Lsh/Vil on mouse chromosome 1.
C H, Barton +3 more
openaire +2 more sources
The role of CSE1L expression in cervical lymph node metastasis of larynx tumors
Brazilian Journal of Otorhinolaryngology, 2021 Introduction: According to international reports, 30–40% of all head and neck cancers are larynx cancers, comprising 1–2.5% of all cancer types. Cervical nodal involvement has been reported to be 40% and 65% in T3 and T4 cases, respectively.
Tuncay Tunccan +7 more
doaj +1 more source
A Comprehensive View of Human Chromosome 1 [PDF]
Genome Research, 1999 Comprehensive representations of human chromosomes combining diverse genomic data sets, localizing expressed sequences, and reflecting physical distance are essential for disease gene identification and sequencing efforts. We have developed a method (CompView) for integrating genomic information derived from available cytogenetic, genetic linkage ...
P S, White +3 more
openaire +2 more sources
Nature Communications, 2019 Centriolar separation is thought to be crucial for centriole duplication, but the mechanism behind separation is poorly understood. Here, using micropatterning, the authors report that actomyosin forces influence the direction, distance, and time of ...
Elisa Vitiello +7 more
doaj +1 more source
Distinct TERB1 Domains Regulate Different Protein Interactions in Meiotic Telomere Movement
Cell Reports, 2017 Summary: Meiotic telomeres attach to the nuclear envelope (NE) and drive the chromosome movement required for the pairing of homologous chromosomes. The meiosis-specific telomere proteins TERB1, TERB2, and MAJIN are required to regulate these events, but
Jingjing Zhang +3 more
doaj +1 more source
Association analysis of chromosome 1 migraine candidate genes
BMC Medical Genetics, 2007 Background Migraine with aura (MA) is a subtype of typical migraine. Migraine with aura (MA) also encompasses a rare severe subtype Familial Hemiplegic Migraine (FHM) with several known genetic loci.
MacMillan John +5 more
doaj +1 more source
Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas
Pediatric Blood &Cancer, EarlyView.ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall +2 more
wiley +1 more source