Detection of chromosome aberrations in metaphase and interphase tumor cells by in situ hybridization using chromosome-specific library probes [PDF]
Chromosome aberrations in two glioma cell lines were analyzed using biotinylated DNA library probes that specifically decorate chromosomes 1, 4, 7, 18 and 22 from pter to qter.
A Al-Saadi +38 more
core +1 more source
Combining chromosomal arm status and significantly aberrant genomic locations reveals new cancer subtypes [PDF]
Many types of tumors exhibit chromosomal losses or gains, as well as local amplifications and deletions. Within any given tumor type, sample specific amplifications and deletionsare also observed.
Domany, Eytan +4 more
core +4 more sources
Rapid metaphase and interphase detection of radiation-induced chromosome aberrations in human lymphocytes by chromosomal suppression in situ hybridization [PDF]
Chromosomal in situ suppression (CISS)-hybridization of biotinylated phage DNA-library inserts from sorted human chromosomes was used to decorate chromosomes 1 and 7 specifically from pter to qter and to detect structural aberrations of these chromosomes
Cremer, Christoph +4 more
core +1 more source
Prenatal Sonographic Features of Rare Chromosome 13 Aberrations
Hanna Moczulska,1 Michal Pietrusinski,1 Marcin Serafin,1 Beata Skoczylas,1 Piotr Sieroszewski,2 Maciej Borowiec1 1Department of Clinical Genetics, Medical University of Lodz, Lodz, Poland; 2Department of Fetal Medicine and Gynecology, Medical University ...
Moczulska H +5 more
doaj
The process of karyotype evolution in Cervidae from a common ancestor (2n = 70, FN = 70) has been marked by complex chromosomal rearrangements. This ancestral karyotype has been retained by the current species Mazama gouazoubira (Fischer 1814), for which
Iara Maluf Tomazella +2 more
doaj +1 more source
Calculating variations in biological effectiveness for a 62 MeV proton beam
A biophysical model of radiation-induced cell death and chromosome aberrations (called BIANCA, BIophysical ANalysis of Cell death and chromosome Aberrations) was further developed and applied to therapeutic protons.
Mario Pietro Carante +3 more
doaj +1 more source
Induction of chromosome damage by ultraviolet light and caffeine: Correlation of cytogenetic evaluation and flow karyotype [PDF]
Asynchrononously growing cells of a M3-1 Chinese hamster line were ultraviolet (UV) irradiated ( = 254 nm) with UV fluences up to 7.5 J/m2. After irradiation, cells were incubated with or without 2 mM caffeine for 20 hr, then mitotic cells were selected ...
Carrano +20 more
core +1 more source
Clinical cytogenetics in river buffalo
While autosomal numeric chromosome abnormalities are phenotipically visible (abnormal body conformation) and easily eliminated during the normal breeding selection, sex numeric abnormalities (including the cases of free-martinism), as well as the ...
L. Zicarelli +3 more
doaj +1 more source
The P genome of Agropyron cristatum Gaertn. contains many desirable genes that can be utilized as genetic resources to improve wheat. In this research, we used both the gametocidal chromosome 2Cc and the pairing homologous gene (Ph1b) mutant to induce ...
Alejandro Copete-Parada +2 more
doaj +1 more source
Chromosome breakage after G2 checkpoint release [PDF]
DNA double-strand break (DSB) repair and checkpoint control represent distinct mechanisms to reduce chromosomal instability. Ataxia telangiectasia (A-T) cells have checkpoint arrest and DSB repair defects. We examine the efficiency and interplay of ATM's
Beucher, Andrea +8 more
core +4 more sources

