Results 231 to 240 of about 1,593,998 (268)

A bipartite mechanism for condensin II activation in mitosis

open access: yes
Tetiker D   +9 more
europepmc   +1 more source

Targeted Chromosome Conformation Capture (HiCap)

open access: yesMethods in Molecular Biology, 2022
Targeted chromosome conformation capture (HiCap) is an experimental method for detecting spatial interactions of genomic features such as promoters and/or enhancers. The protocol first describes the design of sequence capture probes.
Pelin Sahlén, Artemy Zhigulev
exaly   +2 more sources

Getting an A with the 3Cs: Chromosome Conformation Capture for Undergraduates

Journal of Visualized Experiments, 2023
Chromosome conformation capture (3C) is a powerful tool that has spawned a family of similar techniques (e.g., Hi-C, 4C, and 5C, referred to here as 3C techniques) that provide detailed information of the three-dimensional organization of chromatin. The 3C techniques have been used in a wide range of studies, from monitoring the changes in chromatin ...
Joniec, Acadia   +4 more
openaire   +2 more sources

Subtelomeric Chromatin Structure by Chromosome Conformation Capture (3C)-qPCR Methodology in Candida glabrata

2022
Chromatin architecture has an enormous impact on gene regulation, DNA replication, repair, and packaging. Chromatin is organized in a complex hierarchical manner in which distant fragments of DNA can interact with each other through DNA loops. DNA loops can interact between themselves to form topologically associated domains (TADs) that are further ...
Eunice, López-Fuentes   +3 more
openaire   +2 more sources

Analysis of Interactions Between Genomic Loci Through Chromosome Conformation Capture (3C)

Current Protocols in Cell Biology, 2012
AbstractGenome architecture plays a significant role in the regulation of DNA‐based cellular processes such as transcription and recombination. The successful accomplishment of these processes involves coordinated interaction of DNA elements located at a distance from each other. The ‘Chromosome Conformation Capture’ (3C) assay is a convenient tool for
Belal, El Kaderi   +2 more
openaire   +2 more sources

Chromosome Conformation Capture (3C) of Tandem Arrays in Yeast

2014
Studying interphase chromosome arrangements at the molecular level can provide important details on the function and coordination of many metabolic processes that take place on DNA, such as transcription or DNA repair. The chromosome conformation capture (3C) methodology was originally developed in yeast to study the interphase organization of a single-
Maria D, Mayán, Luis, Aragón
openaire   +2 more sources

The Chromosome Conformation Capture (3C) in Drosophila melanogaster

2020
The discovery of the DNA double helix by Watson and Crick in 1953 was the first report showing that the genomic information is not contained in a stretched linear molecule. After that, a huge advance in the knowledge of the structure of the eukaryotic genome in the nuclear space has been made over the last decades, bringing us to the widely accepted ...
openaire   +2 more sources

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