GENESPACE tracks regions of interest and gene copy number variation across multiple genomes
The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
J. Lovell+8 more
semanticscholar +1 more source
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Integrating Hi-C links with assembly graphs for chromosome-scale assembly
Motivation Long-read sequencing and novel long-range assays have revolutionized de novo genome assembly by automating the reconstruction of reference-quality genomes.
Jay Ghurye+7 more
semanticscholar +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
Biogeography and Phylogeny of Wood-feeding Cockroaches in the Genus Cryptocercus
Subsocial, xylophagous cockroaches of the genus Cryptocercus exhibit a disjunct distribution, with representatives in mature montane forests of North America, China, Korea and the Russian Far East.
Kiyoto Maekawa, Christine A. Nalepa
doaj +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
Large chromosomal structural variations between M. acuminata and M balbisiana and their consequences on chromosome recombination and segregation in a AAAB polyploidy context [PDF]
Many banana cultivars are triploid interspecific hybrids between M. acuminata (Genome A, 2n=22) and M. balbisiana (Genome B, 2n=22). They included the important group of Plantain cooking bananas classified as AAB.
Baurens, Franc-Christophe+7 more
core
Chromosome number and satellited chromosome morphology of eleven species of Arachis (Leguminosae)
The chromosome number was determined in eleven recently-described species of Arachís belonging to five different axonomic sections. Two new species of section Arachís, A. Gregoryí and A.
Andréa del Pilar De Souza Penaloza+1 more
doaj
Ornithogalum insulare (Hyacinthaceae): A new species from the Cretan area (S. Aegean, Greece) [PDF]
Ornithogalum insulare collected from three offshore islets of Crete is described as a species new to science. It is illustrated and compared with other related species of the genus. Information regarding its chromosome number (2n = 44) and karyotype is
Zacharias Kypriotakis+2 more
doaj +1 more source
CHROMOSOME NUMBER AND THE MUTATION RATE IN AVENA AND TRITICUM.
Changes were observed from miniature-alpha to beta and gamma, from niniature-beta to gamma, and from miniature-gamma to alpha and beta. Miniature-alpha appears to be the most unstable and miniature-beta the most stable of the three mutable miniature ...
L. Stadler
semanticscholar +1 more source