Results 91 to 100 of about 1,413,988 (356)
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin+14 more
wiley +1 more source
Chromosome number and satellited chromosome morphology of eleven species of Arachis (Leguminosae)
The chromosome number was determined in eleven recently-described species of Arachís belonging to five different axonomic sections. Two new species of section Arachís, A. Gregoryí and A.
Andréa del Pilar De Souza Penaloza+1 more
doaj
Men Can't Always be Transformed into Mice: Decision Algorithms and Complexity for Sorting by Symmetric Reversals [PDF]
Sorting a permutation by reversals is a famous problem in genome rearrangements. Since 1997, quite some biological evidence were found that in many genomes the reversed regions are usually flanked by a pair of inverted repeats. This type of reversals are called symmetric reversals, which, unfortunately, were largely ignored until recently.
arxiv
Metaphase Configurations in Drosophila: A Comparison of Endemic Hawaiian Species and Non-Endemic Species [PDF]
The metaphase configurations of 400 strains from 63 species of Hawaiian Drosophila were determined from squash preparations of larval brain tissue or spermatogenic cells from adult testes.
Clayton, Frances E.
core +2 more sources
Biomarkers of leukemia risk: benzene as a model. [PDF]
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core +3 more sources
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita+1 more
wiley +1 more source
Plântulas de Cybistax antisyphilitica (ipê-verde), espécie arbórea que ocorre no Estado de São Paulo, Brasil, foram estudadas morfoanatomicamente e citogeneticamente. As plântulas são eudicotiledôneas, fanerocotiledonares e epigéias.
Flavia Aparecida Ortolani+4 more
doaj +1 more source
The parameters of Menzerath-Altmann law in genomes [PDF]
The relationship between the size of the whole and the size of the parts in language and music is known to follow Menzerath-Altmann law at many levels of description (morphemes, words, sentences...). Qualitatively, the law states that larger the whole, the smaller its parts, e.g., the longer a word (in syllables) the shorter its syllables (in letters ...
arxiv +1 more source
Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer
We used whole exome and RNA‐sequencing to profile divergent genomic and transcriptomic landscapes of microsatellite stable (MSS) and microsatellite instable (MSI) colorectal cancer. Alterations were classified using a computational score for integrative cancer variant annotation and prioritization.
Efstathios‐Iason Vlachavas+15 more
wiley +1 more source
Artemisia herba-alba is a largely-distributed and often landscape-dominating taxon in arid areas of the Mediterranean and Irano-Turanian regions. In Algeria, in 2010 its communities covered 10% of the steppe territory, but its populations have been ...
Youcef Bougoutaia+4 more
doaj +1 more source