Results 91 to 100 of about 10,937,438 (374)

GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

open access: yeseLife, 2022
The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
J. Lovell   +8 more
semanticscholar   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

open access: yesMolecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin   +14 more
wiley   +1 more source

Integrating Hi-C links with assembly graphs for chromosome-scale assembly

open access: yesbioRxiv, 2018
Motivation Long-read sequencing and novel long-range assays have revolutionized de novo genome assembly by automating the reconstruction of reference-quality genomes.
Jay Ghurye   +7 more
semanticscholar   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Biogeography and Phylogeny of Wood-feeding Cockroaches in the Genus Cryptocercus

open access: yesInsects, 2011
Subsocial, xylophagous cockroaches of the genus Cryptocercus exhibit a disjunct distribution, with representatives in mature montane forests of North America, China, Korea and the Russian Far East.
Kiyoto Maekawa, Christine A. Nalepa
doaj   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu   +15 more
wiley   +1 more source

Large chromosomal structural variations between M. acuminata and M balbisiana and their consequences on chromosome recombination and segregation in a AAAB polyploidy context [PDF]

open access: yes, 2017
Many banana cultivars are triploid interspecific hybrids between M. acuminata (Genome A, 2n=22) and M. balbisiana (Genome B, 2n=22). They included the important group of Plantain cooking bananas classified as AAB.
Baurens, Franc-Christophe   +7 more
core  

Chromosome number and satellited chromosome morphology of eleven species of Arachis (Leguminosae)

open access: yesBonplandia, 2005
The chromosome number was determined in eleven recently-described species of Arachís belonging to five different axonomic sections.  Two new species  of section  Arachís, A. Gregoryí and A.
Andréa del Pilar De Souza Penaloza   +1 more
doaj  

Ornithogalum insulare (Hyacinthaceae): A new species from the Cretan area (S. Aegean, Greece) [PDF]

open access: yesBotanica Serbica, 2018
Ornithogalum insulare collected from three offshore islets of Crete is described as a species new to science. It is illustrated and compared with other related species of the genus. Information regarding its chromosome number (2n = 44) and karyotype is
Zacharias Kypriotakis   +2 more
doaj   +1 more source

CHROMOSOME NUMBER AND THE MUTATION RATE IN AVENA AND TRITICUM.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1929
Changes were observed from miniature-alpha to beta and gamma, from niniature-beta to gamma, and from miniature-gamma to alpha and beta. Miniature-alpha appears to be the most unstable and miniature-beta the most stable of the three mutable miniature ...
L. Stadler
semanticscholar   +1 more source

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