Results 71 to 80 of about 11,109,446 (394)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Polygonatum cyrtonema var. gutianshanicum——A new variety of Polygonatum cyrtonema and comparative studies on it and the similar species

open access: yes浙江大学学报. 农业与生命科学版, 2002
In this paper, a new variety of Polygonatum cyrtonema——P. cyrtonema var. guitanshancum was discribed. Karyotypical and morphological studies of it and the similar specics were also giv en.
JIN Xiao feng   +2 more
doaj   +1 more source

GENESPACE tracks regions of interest and gene copy number variation across multiple genomes

open access: yeseLife, 2022
The development of multiple chromosome-scale reference genome sequences in many taxonomic groups has yielded a high-resolution view of the patterns and processes of molecular evolution.
J. Lovell   +8 more
semanticscholar   +1 more source

Natural selection reduced diversity on human Y chromosomes [PDF]

open access: yes, 2013
The human Y chromosome exhibits surprisingly low levels of genetic diversity. This could result from neutral processes if the effective population size of males is reduced relative to females due to a higher variance in the number of offspring from males
Lohmueller, Kirk E.   +2 more
core   +5 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Large chromosomal structural variations between M. acuminata and M balbisiana and their consequences on chromosome recombination and segregation in a AAAB polyploidy context [PDF]

open access: yes, 2017
Many banana cultivars are triploid interspecific hybrids between M. acuminata (Genome A, 2n=22) and M. balbisiana (Genome B, 2n=22). They included the important group of Plantain cooking bananas classified as AAB.
Baurens, Franc-Christophe   +7 more
core  

Massive gene amplification on a recently formed Drosophila Y chromosome. [PDF]

open access: yes, 2019
Widespread loss of genes on the Y is considered a hallmark of sex chromosome differentiation. Here we show that the initial stages of Y evolution are driven by massive amplification of distinct classes of genes. The neo-Y chromosome of Drosophila miranda
Bachtrog, Doris   +2 more
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

open access: yesFEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona   +4 more
wiley   +1 more source

A new species in the Hieracium lycopifolium agg. (Asteraceae) from the Western Carpathians

open access: yesActa Societatis Botanicorum Poloniae, 2011
Hieracium zajacii Szeląg is described from the Vel'ká Fatra Mts in Slovakia. It is the first representative of H. lycopifolium agg. to be found in the Carpathians. The new species is tetraploid (2n = 36) and reproduces apomictically.
Zbigniew Szeląg
doaj   +1 more source

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