Results 11 to 20 of about 204,438 (143)

Constructing Auxin-Inducible Degron Mutants Using an All-in-One Vector

open access: yesPharmaceuticals, 2020
Conditional degron-based methods are powerful for studying protein function because a degron-fused protein can be rapidly and efficiently depleted by adding a defined ligand.
Aisha Yesbolatova   +2 more
doaj   +1 more source

Chromosome Organization: Original Condensins [PDF]

open access: yesCurrent Biology, 2014
Two new studies reveal the main actors involved in the resolution and segregation of newly replicated origins in bacteria. These results have important implications for our understanding of the mechanisms involved in precisely coordinating chromosome organization, segregation and replication.
Diego I. Cattoni   +2 more
openaire   +2 more sources

Bacterial chromosome segregation by the ParABS system [PDF]

open access: yesOpen Biology, 2020
Proper chromosome segregation during cell division is essential in all domains of life. In the majority of bacterial species, faithful chromosome segregation is mediated by the tripartite ParABS system, consisting of an ATPase protein ParA, a CTPase and ...
Adam S. B. Jalal, Tung B. K. Le
doaj   +1 more source

MukBEF, a Chromosomal Organizer [PDF]

open access: yesMicrobial Physiology, 2014
Global folding of bacterial chromosome requires the activity of condensins. These highly conserved proteins are involved in various aspects of higher-order chromatin dynamics in a diverse range of organisms. Two distinct superfamilies of condensins have been identified in bacteria.
Valentin V, Rybenkov   +3 more
openaire   +2 more sources

Control of Smc Coiled Coil Architecture by the ATPase Heads Facilitates Targeting to Chromosomal ParB/parS and Release onto Flanking DNA

open access: yesCell Reports, 2016
Smc/ScpAB promotes chromosome segregation in prokaryotes, presumably by compacting and resolving nascent sister chromosomes. The underlying mechanisms, however, are poorly understood.
Anita Minnen   +5 more
doaj   +1 more source

SMC condensin entraps chromosomal DNA by an ATP hydrolysis dependent loading mechanism in Bacillus subtilis

open access: yeseLife, 2015
Smc–ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic basis for its action, however, is only poorly understood. Here, we have established a physical
Larissa Wilhelm   +6 more
doaj   +1 more source

Nuclear Organization and Chromosome Segregation [PDF]

open access: yesThe Plant Cell, 1999
The genetic information underlying plant form and function is contained within the cell nucleus in the form of complex, dynamic DNA–protein structures—the chromosomes. The faithful transmission of these structures during mitosis and meiosis requires extensive chromosome reorganization and ...
A E, Franklin, W Z, Cande
openaire   +3 more sources

Spatial organization of bacterial chromosomes [PDF]

open access: yesCurrent Opinion in Microbiology, 2014
Bacterial chromosomes are organized in stereotypical patterns that are faithfully and robustly regenerated in daughter cells. Two distinct spatial patterns were described almost a decade ago in our most tractable model organisms. In recent years, analysis of chromosome organization in a larger and more diverse set of bacteria and a deeper ...
Xindan, Wang, David Z, Rudner
openaire   +2 more sources

Organization of the bacterial chromosome [PDF]

open access: yesMicrobiological Reviews, 1990
Recent progress in studies on the bacterial chromosome is summarized. Although the greatest amount of information comes from studies on Escherichia coli, reports on studies of many other bacteria are also included. A compilation of the sizes of chromosomal DNAs as determined by pulsed-field electrophoresis is given, as well as a discussion of factors ...
S, Krawiec, M, Riley
openaire   +2 more sources

Novel Divisome-Associated Protein Spatially Coupling the Z-Ring with the Chromosomal Replication Terminus in Caulobacter crescentus

open access: yesmBio, 2020
Cell division requires proper spatial coordination with the chromosome, which undergoes dynamic changes during chromosome replication and segregation. FtsZ is a bacterial cytoskeletal protein that assembles into the Z-ring, providing a platform to build ...
Shogo Ozaki, Urs Jenal, Tsutomu Katayama
doaj   +1 more source

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