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Smc–ScpAB forms elongated, annular structures that promote chromosome segregation, presumably by compacting and resolving sister DNA molecules. The mechanistic basis for its action, however, is only poorly understood. Here, we have established a physical
Larissa Wilhelm +6 more
doaj +1 more source
A conserved filamentous assembly underlies the structure of the meiotic chromosome axis. [PDF]
The meiotic chromosome axis plays key roles in meiotic chromosome organization and recombination, yet the underlying protein components of this structure are highly diverged.
Caballero, Iracema +10 more
core +4 more sources
Nuclear Organization and Chromosome Segregation [PDF]
The genetic information underlying plant form and function is contained within the cell nucleus in the form of complex, dynamic DNA–protein structures—the chromosomes. The faithful transmission of these structures during mitosis and meiosis requires extensive chromosome reorganization and ...
A E, Franklin, W Z, Cande
openaire +3 more sources
The architecture of chicken chromosome territories changes during differentiation [PDF]
BACKGROUND: Between cell divisions the chromatin fiber of each chromosome is restricted to a subvolume of the interphase cell nucleus called chromosome territory.
Bonifer, C. +7 more
core +4 more sources
Chromosome Oscillations in Mitosis [PDF]
Successful cell division requires a tight regulation of chromosome motion via the activity of molecular motors. Many of the key players at the origin of the forces generating the movement have been identified, but their spatial and temporal organization ...
A. P. Joglekar +8 more
core +2 more sources
Organization of the bacterial chromosome [PDF]
Recent progress in studies on the bacterial chromosome is summarized. Although the greatest amount of information comes from studies on Escherichia coli, reports on studies of many other bacteria are also included. A compilation of the sizes of chromosomal DNAs as determined by pulsed-field electrophoresis is given, as well as a discussion of factors ...
S, Krawiec, M, Riley
openaire +2 more sources
Prime movers : mechanochemistry of mitotic kinesins [PDF]
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
A Blangy +184 more
core +1 more source
Organization of the Mitotic Chromosome [PDF]
Chromosome Conundrum The three-dimensional organization of chromosomal DNA within the cell nucleus plays an important role in gene regulation. Naumova et al. (p.
Naumova, Natalia +6 more
openaire +4 more sources
Auxin-inducible degron systems can be leaky and require high doses of auxin. Here the authors establish AID2 which uses an OsTIR1 mutant and the ligand 5-Ph-IAA to overcome these problems and establish AID-mediated target depletion in mice.
Aisha Yesbolatova +13 more
doaj +1 more source
VISUALIZING CHROMOSOME STRUCTURE/ORGANIZATION
▪ Abstract With the rapid development of sequencing technologies in the past decade, many eukaryotic genomes have been resolved at the primary sequence level. However, organization of the genome within nuclei and the principles that govern such properties remain largely unclear.
Eric, Lam +2 more
openaire +3 more sources

