KegAlign: optimizing pairwise alignments with diagonal partitioning. [PDF]
Gulhan AB +5 more
europepmc +1 more source
Treatment of pediatric epilepsy
Anti‐seizure medications are the first‐line treatment for the vast majority of children with epilepsy, with the advantages of non‐invasive wide adaptability. Surgery is the main treatment for drug‐resistant epilepsy and lesion‐related epilepsy, which can cure some cases of epilepsy in children. A ketogenic diet is often an add‐on therapy.
Junxiao Li +8 more
wiley +1 more source
The ParB-CTP cycle activates phase separation in bacterial DNA segregation. [PDF]
Delimi L +5 more
europepmc +1 more source
Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan +5 more
wiley +1 more source
Chromosome and megaplasmid partitioning in Thermus thermophilus HB27 [PDF]
Replicon segregation was studied in Thermus thermophilus which is a thermophilic polyploid bacterium and contains several copies of a chromosome and a megaplasmid. Both the chromosome and the megaplasmid encode par gene homologues (parABc and parABm, respectively), and the chromosome also carries a mreB homologue.
openaire
The combination of active partitioning and toxin-antitoxin systems is most advantageous for low-copy plasmid fitness. [PDF]
Effe J +5 more
europepmc +1 more source
Wheat breeding approaches for designing wheat to thrive in a warmer world
Wheat is a vital food crop, accounting for approximately 20% of daily calories and protein consumed worldwide. However, modern‐day wheat is under pressure from global change. The improvement rate of wheat yields is not keeping up with the demand of our growing population. Furthermore, abiotic and biotic stressors are becoming more prevalent. This paper
Jake Hill, Surbhi Grewal, Stella Edwards
wiley +1 more source
Model-based partition scheduling of integrated modular avionics systems using genetic algorithm. [PDF]
Chen J, Zhai Z, Han P, Huang M.
europepmc +1 more source
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long +7 more
wiley +1 more source
Elucidating the susceptibility genes between insomnia and migraine by integrating genetic data and transcriptomes. [PDF]
Wang T, Li J, Yao Y, Wang H, Zheng X.
europepmc +1 more source

