Competitive binding of MatP and topoisomerase IV to the MukB hinge domain [PDF]
eLife, 2021 Structural Maintenance of Chromosomes (SMC) complexes have ubiquitous roles in compacting DNA linearly, thereby promoting chromosome organization-segregation.
Gemma LM Fisher +10 more
doaj +8 more sources
A novel structural maintenance of chromosomes (SMC)-related protein family specific to Archaea [PDF]
Frontiers in Microbiology, 2022 The ATPases belonging to the structural maintenance of chromosomes (SMC) superfamily are involved in the maintenance of chromosome organization and dynamics, as well as DNA repair.
Mari Yoshinaga +4 more
doaj +5 more sources
DNA sliding and loop formation by E. coli SMC complex: MukBEF [PDF]
Biochemistry and Biophysics Reports, 2022 SMC (structural maintenance of chromosomes) complexes share conserved architectures and function in chromosome maintenance via an unknown mechanism. Here we have used single-molecule techniques to study MukBEF, the SMC complex in Escherichia coli.
Man Zhou
doaj +2 more sources
MukBEF-dependent chromosomal organization in widened Escherichia coli [PDF]
Frontiers in Microbiology, 2023 The bacterial chromosome is spatially organized through protein-mediated compaction, supercoiling, and cell-boundary confinement. Structural Maintenance of Chromosomes (SMC) complexes are a major class of chromosome-organizing proteins present throughout
Aleksandre Japaridze +5 more
doaj +2 more sources
MukB Is a Gene Necessary for Rapid Proliferation of Vibrio vulnificus in the Systemic Circulation but Not at the Local Infection Site in the Mouse Wound Infection Model [PDF]
Microorganisms, 2021 Vibrio vulnificus causes rapid septicemia in susceptible individuals who have ingested contaminated foods or have open wounds exposed to seawater contaminated with the bacteria.
Takashige Kashimoto +4 more
doaj +2 more sources
Involvement of the inner surface residues of bacterial SMC protein MukB in the ssDNA binding in vitro [PDF]
Communications BiologyThe bacterial condensin MukB facilitates proper chromosome segregation in Escherichia coli. MukB protein localizes at the ori adjacent region by unknown mechanism.
Koichiro Akiyama +2 more
doaj +2 more sources
A topological analysis of difference topology experiments of condensin with topoisomerase II [PDF]
Biology Open, 2020 An experimental technique called difference topology combined with the mathematics of tangle analysis has been used to unveil the structure of DNA bound by the Mu transpososome. However, difference topology experiments can be difficult and time consuming.
Soojeong Kim, Isabel K. Darcy
doaj +2 more sources
Transient non-specific DNA binding dominates the target search of bacterial DNA-binding proteins. [PDF]
Mol Cell, 2021 International audienceAbstract The global emergence of drug-resistant bacteria leads to the loss of efficacy of our antibiotics arsenal and severely limits the success of currently available treatments.
Stracy M +5 more
europepmc +2 more sources
Proteomic analysis of meropenem-induced outer membrane vesicles released by carbapenem-resistant Klebsiella pneumoniae [PDF]
Microbiology SpectrumCarbapenem-resistant Klebsiella pneumoniae (CRKP) is an important multidrug resistance (MDR) pathogen that threatens human health and is the main source of hospital-acquired infection.
Fangfang Fan +3 more
doaj +2 more sources
Dynamic architecture of the Escherichia coli structural maintenance of chromosomes (SMC) complex, MukBEF. [PDF]
Nucleic Acids Res, 2019 Ubiquitous Structural Maintenance of Chromosomes (SMC) complexes use a proteinaceous ring-shaped architecture to organize and individualize chromosomes, thereby facilitating chromosome segregation.
Rajasekar KV +11 more
europepmc +3 more sources